Results 51 to 60 of about 90,616 (309)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Intersectionality queer studies and hybridity: methodological frameworks for social research [PDF]

open access: yes, 2012
This article seeks to draw links between intersectionality and queer studies as epistemological strands by examining their common methodological tasks and by tracing some similar difficulties of translating theory into research methods. Intersectionality
Fotopoulou, Aristea
core   +4 more sources

Hybrid inflation

open access: yesPhysical Review D, 1994
Usually inflation ends either by a slow rolling of the inflaton field, which gradually becomes faster and faster, or by a first-order phase transition. We describe a model where inflation ends in a different way, due to a very rapid rolling (`waterfall') of a scalar field $ $ triggered by another scalar field $ $.
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Translations: a Movement Towards Reconciliation

open access: yesABEI Journal, 2014
This article proposes a postcolonial reading of Brian Friel’s Translations, understanding it as piece of work that presents a way out for Ireland to reconcile with England, its colonizer.
Michelle Andressa Alvarenga de Souza
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Theoretical Study of Social Hybridity

open access: yesAnnali di Ca’ Foscari: Serie Orientale, 2018
The purpose of this paper is to show the new directions for reconstruction of the concept of society made possible by another concept – that of hybridity.
Utsumi, Hirofumi
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

L’hybridité de la lettre galante, ou la transgression innovante

open access: yesQuêtes Littéraires, 2016
This essay concentrates on early modern expressions of literary hybridity in the 17th-century gallant letters of Vincent Voiture (1597-1648), Charles Cotin (1604-1681) and Antoine Godeau (1605 -1672), circulating in the Parisian salon L’Hôtel de ...
Astrid Van Assche
doaj   +1 more source

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