Results 131 to 140 of about 59,780 (293)

Screening individual hybridomas by microengraving to discover monoclonal antibodies

open access: yesNature Protocols, 2009
A. Ogunniyi   +4 more
semanticscholar   +1 more source

Acidic Nanoparticles Prevent HIV Pre‐Exposure Prophylaxis (PrEP)‐Induced Oligodendrocyte Impairments by Restoring Lysosomal pH in Adolescent Models

open access: yesGlia, Volume 73, Issue 10, Page 1967-1988, October 2025.
Main Points Pre‐exposure prophylaxis (PrEP) inhibits oligodendrocyte differentiation PrEP inhibits oligodendrocyte differentiation through lysosome deacidification Acidic nanoparticles prevent PrEP‐induced inhibition of oligodendrocyte differentiation ABSTRACT A disproportionate percentage of adolescents are diagnosed with human immunodeficiency virus (
Caela C. Long   +6 more
wiley   +1 more source

Sequences of variable regions of hybridoma antibodies to alpha (1----6) dextran in BALB/c and C57BL/6 mice. [PDF]

open access: bronze, 1985
S K Sikder   +4 more
openalex   +1 more source

High‐Calorie Diet During Pregnancy Leads to Muscular Fibrosis and Neuromuscular Damage in Offspring Mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Sarcopenia, recognized as an age‐related loss of muscle mass and function, is a critical risk for geriatric health. We previously demonstrated that maternal high‐fat diet (HFD) suppresses mitochondrial biogenesis during fetal skeletal muscle development, but the longitudinal effect of maternal HFD challenge on offspring muscle ...
Jun Seok Son   +5 more
wiley   +1 more source

Skeletal Muscle PGC‐1α Remodels Mitochondrial Phospholipidome but Does Not Alter Energy Efficiency for ATP Synthesis

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background The coupling of oxygen consumption to ATP synthesis via oxidative phosphorylation (OXPHOS) is central for cellular energy homeostasis. Some studies suggest exercise training increases the efficiency of ATP synthesis, but the molecular mechanisms are unclear.
Takuya Karasawa   +7 more
wiley   +1 more source

Drug‐Tolerant, Chemiluminescent Lateral Flow Immunoassay Platform for the Determination of Neutralizing Anti‐Drug Antibodies

open access: yesSmall, Volume 21, Issue 40, October 9, 2025.
Immunogenicity evaluation in patients receiving mAb therapy is becoming the standard of care in healthcare systems worldwide. Nevertheless, current methods for anti‐drug antibody determination suffer from drug interference and/or inability to be performed at the point‐of‐care (POC).
Frans Kokojka   +4 more
wiley   +1 more source

Evaluating the Potential of Galactosaminogalactan as a Diagnostic Target for Invasive Aspergillosis

open access: yesMycoses, Volume 68, Issue 10, October 2025.
ABSTRACT Background Early diagnosis of invasive aspergillosis (IA) is critical for the initiation of effective antifungal therapy. Currently, detection of galactomannan (GM), a secreted fungal glycan, is the most used culture‐independent diagnostic test for IA. However, limitations in the sensitivity and specificity of this test have led to interest in
Takahiro Takazono   +22 more
wiley   +1 more source

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