Results 11 to 20 of about 45,417 (262)

Obtaining Specific Hybridomas for Ki-67 Protein Immunodetection

Indonesian Biomedical Journal, 2021
BACKGROUND: Active proliferation is specific property of a tumor cells. However, the cost of the analysis is high due to commercial anti-Ki-67 mAbs used as the main immunoreagent for reliable identification of proliferating cells.
Aigerim Turgimbayeva, Sailau Abeldenov, Nurgul Sarina, Bekbolat Khassenov, Saule Eskendirova   +4 more
doaj   +1 more source

Obtaining and Characterization of the Monoclonal Antibodies Against G-Protein of the Respiratory Syncytial Virus

Журнал микробиологии, эпидемиологии и иммунобиологии, 2020
The aim of this study was to obtain hybridomas producing monoclonal antibodies (Mabs) to the G-protein of the respiratory syncytial virus (RSV), and to evaluate their immunological characteristics and virus-neutralizing activity.Material and methods ...
N. A. Demidova, R. R. Klimova, A. A. Kushch, E. I. Lesnova, O. V. Masalova, A. D. Dorofeeva, A. A. Nikonova, N. E. Fedorova, V. V. Zverev   +8 more
doaj   +1 more source

Production and characterisation of monoclonal antibodies for the detection of AOZ, a tissue bound metabolite of furazolidone

Veterinární Medicína, 2005
3-amino-2-oxazolidinone (AOZ) is a tissue bound toxic metabolite derived from the nitrofuran antibiotic, furazolidone. AOZ is detected in the derivatised form of 3-{[(2-nitrophenyl) methylene] amino}-2-oxa-zolidinone (NP AOZ).
M. Vass, L. Kotkova, I. Diblikova, Z. Nevorankova, K.M. Cooper, D.G. Kennedy, M. Franek   +6 more
doaj   +1 more source

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

Journal of Experimental Medicine, 1981
We developed a method for production of antigen-specific, H-2-restricted T cell hybrids. The tumor cell partner in the fusions was itself a T cell hybrid, FS6-14.13.AG2 (or its derivatives), which could be induced to produce the growth factor ...
J. Kappler, B. Skidmore, J. White, P. Marrack   +3 more
semanticscholar   +1 more source

Manufacturing of hybridomas, producing monoclonal antibodies against Burkholderia mallei and Burkholderia pseudomallei antigens

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. Obtaining hybridomas, stable producing specific monoclonal antibodies against Burkholderia mallei and Burkholderia pseudomallei antigens. Materials and methods.
G. V. Kuklina, G. D. Elagin, D. V. Pechenkin, O. O. Fomenkov, A. V. Eremkin, A. A. Kytmanov, S. A. Shurupov, S. S. Ipatov   +7 more
doaj   +1 more source

Diversity of the antibody response to tetanus toxoid: comparison of hybridoma library to phage display library. [PDF]

PLoS ONE, 2014
Monoclonal antibodies are important tools in research and since the 1990s have been an important therapeutic class targeting a wide variety of diseases. Earlier methods of mAb production relied exclusively on the lengthy process of making hybridomas. The
Mahsa Sorouri, Sean P Fitzsimmons, Antonina G Aydanian, Sonita Bennett, Marjorie A Shapiro   +4 more
doaj   +1 more source

Development and characterization of novel chimeric monoclonal antibodies for broad spectrum neutralization of rabies virus. [PDF]

PLoS ONE, 2017
Current post-exposure prophylaxis for rabies virus infection has several limitations in terms of supply, cost, safety, and efficacy. Attempts to replace human or equine rabies immune globulins (HRIG or ERIG) have been made by several companies and ...
Pan Kyeom Kim, Sun Ju Keum, Modupe O V Osinubi, Richard Franka, Ji Young Shin, Sang Tae Park, Man Su Kim, Mi Jung Park, Soo Young Lee, William Carson, Lauren Greenberg, Pengcheng Yu, Xiaoyan Tao, Wang Lihua, Qing Tang, Guodong Liang, Madhusdana Shampur, Charles E Rupprecht, Shin Jae Chang   +18 more
doaj   +1 more source

Novel S2 subunit-specific antibody with broad neutralizing activity against SARS-CoV-2 variants of concern

Frontiers in Immunology, 2023
IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), had a major impact on both the global health and economy.
Chang-Kyu Heo, Won-Hee Lim, Won-Hee Lim, Jihyun Yang, Sumin Son, Sang Jick Kim, Doo-Jin Kim, Haryoung Poo, Eun-Wie Cho, Eun-Wie Cho   +9 more
doaj   +1 more source

MANUFACTURING OF HYBRIDOMAS-PRODUCERS OF MONOCLONAL ANTIBODIES TO BRUCELLOSIS AGENT ANTIGENS

Проблемы особо опасных инфекций, 2017
Objective of study is to prepare hybridomas-producers of monoclonal antibodies to brucellosis agent antigens. Materials and methods. B. abortus, B. melitensis, B.
G. V. Kuklina, G. D. Elagin, O. O. Fomenkov, D. V. Pechenkin, A. V. Eremkin, A. A. Kytmanov   +5 more
doaj   +1 more source

Correlation between cell aggregation and antibody production in IgE-producing plasma cells

Biochemistry and Biophysics Reports, 2017
Allergic conditions result in the increase of immunoglobulin (Ig)E-producing plasma cells (IgE-PCs); however, it is unclear how IgE production is qualitatively controlled.
Mari Hikosaka, Akihiko Murata, Miya Yoshino, Shin-Ichi Hayashi   +3 more
doaj   +1 more source