Results 81 to 90 of about 45,417 (262)

Development of a Highly Sensitive Time‐Resolved Fluorescence Immunochromatographic Assay for Rapid Onsite Determination of Prometryn Residues in Food Samples

Food Safety and Health, EarlyView.
The recombinant full‐length antibody against prometryn (PRO‐rAb) was prepared by HEK293 (F) cell expression system and utilized as the foundation for time‐resolved fluorescence immunochromatographic assay (TRFICA). The established method showed good performance for the detection of prometryn residues in five food samples. ABSTRACT Prometryn, a triazine
Jing Zhao, Song Gao, Peipei Li, A. M. Abd El‐Aty, Lingyuan Xu, Fen Jin, Jing Wang, Jia Li, Weiping Lin, Lufei Zheng, Bining Jiao   +10 more
wiley   +1 more source

Retinoic acids inhibit activation-induced apoptosis in T cell hybridomas and thymocytes.

Journal of Immunology, 1992
Apoptosis is induced in immature thymocytes and T cell hybridomas upon stimulation via the TCR/CD3 complex. This phenomenon appears to be related to negative selection of T cell clones in the thymus.
M. Iwata, M. Mukai, Y. Nakai, R. Iseki
semanticscholar   +1 more source

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas.

Journal of Immunology, 1992
We have generated cloned Th1 cells, Th2 cells, and T cell hybridomas specific for the single immunogenic peptide from the beta-chain of murine hemoglobin (Hb(64-76)). The availability of these various types of T cells provided us an unique opportunity to
B. Evavold, S. G. Williams, B. L. Hsu, S. Buus, P. Allen   +4 more
semanticscholar   +1 more source

Protein binding assessment of immobilized nanobody using interferometric nanoporous platform

VIEW, EarlyView.
Nanoporous anodic alumina photonic chip technology is combined with tailor‐engineered “nanobodies”—recombinant variable domains of heavy‐chain‐only antibodies—to achieve high affinity binding to human serum albumin. Abstract Protein sensors are key tools for infectious disease diagnosis and monitoring.
Cheryl Suwen Law, Jayden Revink, Joel Lee, Juan Wang, Andrew D. Abell, Fiona Whelan, Abel Santos   +6 more
wiley   +1 more source

A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses

Infectious Agents and Cancer, 2012
Background Galectin-9 is a mammalian lectin which possesses immunosuppressive properties. Excessive production of galectin-9 has been reported in two types of human virus-associated diseases chronic hepatitis C and nasopharyngeal carcinoma associated to ...
Barjon Clément, Niki Toshiro, Vérillaud Benjamin, Opolon Paule, Bedossa Pierre, Hirashima Mitsuomi, Blanchin Stéphanie, Wassef Michel, Rosen Hugo R, Jimenez Anne-Sophie, Wei Ming, Busson Pierre   +11 more
doaj   +1 more source

B cell growth factors and B cell differentiation factor from human T hybridomas. Two distinct kinds of B cell growth factor and their synergism in B cell proliferation

Journal of Experimental Medicine, 1983
Human T hybridomas secreting B cell growth factors (BCGF) and B cell differentiation factor (BCDF) have been established. Hybrid clones 77- A, 94-C, and 98-F secreted BCGF that induced proliferation of anti-IgM- stimulated normal B cells.
Masaji Okada, Nobuo Sakaguchi, N. Yoshimura, Hideki Hara, Kazuo Shimizu, Nobuaki Yoshida, Kazuyuki Yoshizaki, Susumu Kishimoto, Yuichi Yamamura, Tadamitsu Kishimoto   +9 more
semanticscholar   +1 more source

Production of Monoclonal Antibodies Against the Challenge Strain of Infectious Laryngotracheitis Virus of Chickens and Their Use in an Indirect Immunofluorescent Diagnostic Test [PDF]

Pakistan Veterinary Journal, 2010
The objective of the present research was to produce monoclonal antibodies (MCAs) against the USDA challenge strain of infectious laryngotracheitis virus and to perform an initial investigation of their use in an indirect immunofluorescence diagnostic ...
Ferhat Abbas*, James Andreasen1, Rockey Becker1, Masroor Ahmed, M Arif Awan, Abdul Wadood and Anita Sonn1
doaj  

Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan-induced arthritis [PDF]

, 1995
Frank R. Brennan, Gabriela Negroiu, Edit I. Buzás, Csaba Fülöp, Krisztina Holló, Katalin Mikecz, Tibor T. Glant   +6 more
openalex   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source