Results 31 to 40 of about 4,421 (175)

Trifluoromethylated Quinolone-Hydantoin Hybrids: Synthesis and Antibacterial Evaluation

Sci, 2022
A series of new trifluoromethyl-substituted quinolones and hydantoin hybrids has been synthesized and evaluated against Gram-positive bacterium (Staphylococcus aureus MTCC 96) and Gram-negative bacteria (Pseudomonas aeruginosa MTCC 441, Klebsiella ...
Akhil Mahajan, Harbinder Singh, Amandeep Singh, Devendra K. Agrawal, Amandeep Arora, Tejpal Singh Chundawat   +5 more
doaj   +1 more source

Crystal structures of (S)-(+)-5-(3-bromo/chloro-4-isopropoxyphenyl)-5-methylimidazolidine-2,4-dione

Acta Crystallographica Section E: Crystallographic Communications, 2016
In (S)-(+)-5-(3-bromo-4-isopropoxyphenyl)-5-methylimidazolidine-2,4-dione, C13H15BrN2O3, (I), the hydantoin groups are connected via intermolecular N—H...O hydrogen bonds, forming a terraced sheet structure.
Shigeru Ohba, Minoru Koura, Hisashi Sumida, Kimiyuki Shibuya   +3 more
doaj   +1 more source

Synthesis of Tetracyclic Spirooxindolepyrrolidine-Engrafted Hydantoin Scaffolds: Crystallographic Analysis, Molecular Docking Studies and Evaluation of Their Antimicrobial, Anti-Inflammatory and Analgesic Activities

Molecules, 2023
In a sustained search for novel potential drug candidates with multispectrum therapeutic application, a series of novel spirooxindoles was designed and synthesized via regioselective three-component reaction between isatin derivatives, 2-phenylglycine ...
Amani Toumi, Faiza I.A. Abdella, Sarra Boudriga, Tahani Y. A. Alanazi, Asma K. Alshamari, Ahlam Abdulrahman Alrashdi, Amal Dbeibia, Khaled Hamden, Ismail Daoud, Michael Knorr, Jan-Lukas Kirchhoff, Carsten Strohmann   +11 more
doaj   +1 more source

5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione

Acta Crystallographica Section E, 2008
In the title compound, C10H9FN2O2, the dihedral angle between the hydantoin unit and the benzene ring is 65.55 (5)°. The atoms in the hydantoin ring are coplanar, with a mean deviation of 0.015 Å and a maximum deviation of 0.075 ...
Shahid Hameed, Masahiro Ebihara, M. Khawar Rauf, Abid Hussain, M. Kaleem Kashif   +4 more
doaj   +1 more source

Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance

Chemistry – A European Journal, EarlyView.
This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini, Daniele Lavelli, Alberto Dal Corso, Luca Pignataro   +3 more
wiley   +1 more source

Exploring hydantoin frameworks: synthetic approaches and therapeutic potential

Future Journal of Pharmaceutical Sciences
Background Since its first synthesis in the nineteenth century, hydantoin has emerged as a vital scaffold in drug development, especially for anticonvulsant, antimicrobial, antitumor, and anti-inflammatory agents.
Nirmala V. Shinde, Vrushali P. Patole, Manoj R. Kumbhare, Harsha Narkhede, Ashwini T. Satalkar, Anushka V. Thube, Sachin K. Bhosale   +6 more
doaj   +1 more source

Sequential Ugi reaction/base-induced ring closing/IAAC protocol toward triazolobenzodiazepine-fused diketopiperazines and hydantoins

Beilstein Journal of Organic Chemistry, 2018
A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary ...
Robby Vroemans, Fante Bamba, Jonas Winters, Joice Thomas, Jeroen Jacobs, Luc Van Meervelt, Jubi John, Wim Dehaen   +7 more
doaj   +1 more source

Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines

Química Nova, 2008
Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds.
Silvânia Maria de Oliveira, João Bosco Paraíso da Silva, Marcelo Zaldini Hernandes, Maria do Carmo Alves de Lima, Suely Lins Galdino, Ivan da Rocha Pitta   +5 more
doaj   +1 more source

Solid Shampoo Is Mostly Not Preserved, in Contrast to Liquid Shampoos Used in Hairdressing—A Market Survey in Four European Countries

Contact Dermatitis, EarlyView.
Most solid shampoos (68.6%) did not contain preservatives according to Annex V of the EU Cosmetics Regulation (EC 1223/2009), while all liquid shampoos did. The number of preservatives used was significantly greater in liquid shampoos. ABSTRACT Background Hairdressers are frequently exposed to shampoos, both from neat liquid products and dilutions ...
Wolfgang Uter, Anders B. Funch, Mikkel Bak Jensen, Christoffer Kursawe Larsen, Ying X. Teo, Jeanne D. Johansen, Carola Lidén, Ian R. White   +7 more
wiley   +1 more source

The Pyroglutamate Hydantoin Rearrangement [PDF]

European Journal of Organic Chemistry, 2006
AbstractWhen a mixture of a pyroglutamate and an isocyanate in THF is treated with NaH, a ring transformation occurs leading to functionalised hydantoins. The novel reaction involves a ring‐closing ring‐opening sequence providing a new and straightforward access to an interesting class of heterocyclic compounds.
Nicolai Dieltiens, Diederica D. Claeys, Viktor V. Zhdankin, Victor N. Nemykin, Bart Allaert, Francis Verpoort, Christian V. Stevens   +6 more
openaire   +1 more source