Results 61 to 70 of about 4,421 (175)
Preservatives in Leave‐On Cosmetics Available on the Dutch Market
Contact Dermatitis, EarlyView.
Anton C. de Groot +2 more
wiley +1 more source
New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. [PDF]
PLoS ONE, 2011 BACKGROUND: Oxidative damage to DNA, if not repaired, can be both miscoding and blocking. These genetic alterations can lead to mutations and/or cell death, which in turn cause cancer and aging.
Modesto Redrejo-Rodríguez +6 more
doaj +1 more source
Crucial Role of Oxidation for the Prebiotic Peptide Elongation Promoted by Carbonyl Sulfide
European Journal of Organic Chemistry, Volume 29, Issue 1, January 12, 2026.The prebiotic activation of amino acid (AA) into peptides via N‐carboxyanhydride (NCA), promoted by carbonyl sulfide (COS), cannot proceed without an oxidizing step (enabling better leaving groups than sulfur dianion). While being efficient even at mild pH the prebiotic scope of COS promoted activation of AA, it is however limited because side ...
Alexandre Desfoux +4 more
wiley +1 more source
Hydantoin-Based Molecular Photoswitches
The Journal of Organic Chemistry, 2015 A new family of molecular photoswitches based on arylidenehydantoins is described together with their synthesis and photochemical and photophysical studies. A series of hydantoin derivatives have been prepared as single isomers using simple and versatile chemistry in good yields.
Martinez Lopez, David +7 more
openaire +3 more sources
Bioinspired Light‐Driven Organic Rotary Molecular Systems
ChemistryEurope, Volume 4, Issue 1, January 2026.This review explores the evolution of bioinspired light‐driven rotary molecular systems (RMSs), highlighting the integration of natural chromophore‐based fragments to enhance quantum efficiency, photostability, and biocompatibility. Key strategies to optimize photochemical performance and broaden functional applications are discussed, providing a ...
Lidia Hortigüela, Sara P. Morcillo
wiley +1 more source
Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds
ChemMedChem, Volume 21, Issue 2, January 2026.Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley +1 more source
ChemMedChem, Volume 21, Issue 1, January 2026.A streamlined Ullmann‐Goldberg strategy enabled the synthesis of benzo[b]thiophene‐2‐carboxamides, promising ligands of the pro‐inflammatory RAGE receptor involved in inflammaging and age‐related diseases. LC‐MS, NMR, X‐ray and DFT studies elucidated the copper‐catalyzed mechanism. The lead compound, 3t’, shows inhibitory activity on the sRAGE/AGE2‐BSA
Lisa Bonin +10 more
wiley +1 more source
Antinociceptive Effect of Hydantoin 3-Phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione in Mice
Molecules, 2015 Imidazolidine derivatives, or hydantoins, are synthetic compounds with different therapeutic applications. Many imidazolidine derivatives have psychopharmacological properties, such as phenytoin, famous for its anticonvulsant efficacy, but also effective
Ronaldo Bezerra de Queiroz +11 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic CommunicationsIn the title molecule, C21H17N3O2, the five-membered ring is slightly ruffled and dihedral angles between the pendant six-membered rings and the central, five-membered ring vary between 50.78 (4) and 86.78 (10)°.
Abderrazzak El Moutaouakil Ala Allah +5 more
doaj +1 more source