Results 11 to 20 of about 3,489 (193)

Solvent effects on the structure-property relationship of anticonvulsant hydantoin derivatives: A solvatochromic analysis [PDF]

open access: yesChemistry Central Journal, 2011
Considering the pharmaceutical importance of hydantoins, a set of 25 derivatives of phenytoin, nirvanol and 5-methyl-5-phenylhydantoin, the lipophilicities of which were gradually increased by the introduction of different alkyl, cycloalkyl and alkenyl ...
Trišović Nemanja   +2 more
doaj   +2 more sources

Phase-Transfer-Catalyzed Alkylation of Hydantoins [PDF]

open access: yesACS Organic & Inorganic Au, 2022
Thomas Keenan   +2 more
doaj   +2 more sources

Influence of electrochemical conditions on the regio- and stereoselectivity of selenocyclization of alkenyl hydantoins [PDF]

open access: yesJournal of the Serbian Chemical Society, 2021
5-Alkenyl hydantoins and alkenyl spirohydantoins are converted into bicyclic and tricyclic hydantoins, under indirect electrochemical conditions, generating the phenylselenyl cation in situ. The reactions proceeded in good to exelent yields.
Šmit Biljana M.   +4 more
doaj   +1 more source

Enantioseparation of syn- and anti-3,5-Disubstituted Hydantoins by HPLC and SFC on Immobilized Polysaccharides-Based Chiral Stationary Phases

open access: yesSeparations, 2022
The enantioseparation of syn- and anti-3,5-disubstituted hydantoins 5a–i was investigated on three immobilized polysaccharide-based columns (CHIRAL ART Amylose-SA, CHIRAL ART Cellulose-SB, CHIRAL ART Cellulose-SC) by high performance liquid ...
Mladenka Jurin   +3 more
doaj   +1 more source

Design, Synthesis, Bioevaluation, and Bioinformatics Study of 5-Benzylidene Hydantoin Derivatives as Novel Tyrosine Kinase Inhibitors. [PDF]

open access: yesChemistryOpen
A series of 5‐benzylidene hydantoin derivatives is synthesized and evaluated against eight receptor tyrosine kinases (RTKs). Several compounds show selective and moderate inhibition of human epidermal growth factor receptor 2 (HER2). Molecular docking reveals key interactions with the HER2 active site, highlighting the potential of 5‐benzylidene ...
Naufal M   +4 more
europepmc   +2 more sources

Synthesis of series of different imidazolidine-2,4-dione derivatives and evaluation of their antimicrobial potential [PDF]

open access: yesKragujevac Journal of Science, 2022
A series of twenty two different imidazolidine-2,4-dione derivatives, divided according to their structure into five groups, including alkyl, alkenyl or aryl 5,5disubstituted hydantoins, spirohydantoins, and fused bicyclic and tricyclic hydantoins, was ...
Šmit Biljana   +5 more
doaj   +1 more source

A Cross-Sectional Study of Contact Allergens in Hotel Personal Care Products in Canada, the United States and Europe. [PDF]

open access: yesContact Dermatitis
This study provides evidence of contact allergens in commonly provided hotel personal care products. Patients and clinicians should advocate for improved labelling of contact allergens in hotel personal care products. Additionally, hotels should offer low‐allergen alternatives for at‐risk guests.
Viltakis V, Kirchhof MG.
europepmc   +2 more sources

Synthesis, structure and solvatochromism of 5-methyl-5-(3- or 4-substituted phenyl)hydantoins [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
Several 5-methyl-5-(3- or 4-substituted phenyl)hydantoins were prepared and their ultraviolet absorption spectra were recorded in the region 200–400 nm in twelve solvents of different polarity. The effect of solvent dipo¬larity/polarizability and solvent/
NATALIJA D. DIVJAK   +3 more
doaj   +3 more sources

Comparative Genomic and Transcriptomic Analysis Reveals Why Paenarthrobacter Strains Are Specialists in the Degradation of the Fungicide Iprodione. [PDF]

open access: yesMicrob Biotechnol
Paenarthrobacter are specialists in degrading the fungicide iprodione. We showed that this trait has evolved through gene duplication of ipaH and ddaH genes, being in the core genome of paenarthrobacters, and further genetic optimisation, with different strains being at different evolution stages depending on their prior exposure to iprodione ...
Michelioudakis V   +7 more
europepmc   +2 more sources

Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains

open access: yesAntibiotics, 2023
In this study, a search for new therapeutic agents that may improve the antibacterial activity of conventional antibiotics and help to successfully overcome methicillin-resistant Staphylococcus aureus (MRSA) infections has been conducted.
Karolina Witek   +11 more
doaj   +1 more source

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