Results 41 to 50 of about 3,541 (213)
Synthesis and investigation of solvent effects on the ultraviolet absorption spectra of 1, 3-bis-substituted-5, 5-dimethylhydantoins [PDF]
A series of 1,3-bis-substituted-5,5-dimethylhydantoins was synthesized using the reaction of 5,5-dimethylhydantoin with the corresponding alkyl halide in the presence of trimethylamine as catalyst and sodium hydroxide, according to a modified literature ...
Ušćumlić Gordana S. +2 more
doaj +3 more sources
Protein Adductomics: Methodologies for Untargeted Screening of Adducts to Serum Albumin and Hemoglobin in Human Blood Samples. [PDF]
The reaction products of electrophiles in vivo can be measured as adducts to the abundant proteins, hemoglobin (Hb), and human serum albumin (HSA), in human blood samples.
Carlsson, Henrik +2 more
core +2 more sources
ヒスチジンタグを持つホスファカンコア蛋白の大腸菌での発現と精製 [PDF]
Specific regions of core protein of phosphacan, one of the chondroitin sulfate proteoglycans, were expressed as fusion proteins with histidine-tag (His-tag) in Escherichia coli (E.coli) and were affinity purified using nickel-nitrilotriacetic acid (Ni ...
Ito, Sekiko, Mori, Shuji, Okamoto, Motoi
core +1 more source
A systematic approach to diverse, lead-like scaffolds from α,α-disubstituted amino acids. [PDF]
A powerful strategy for the efficient lead-oriented synthesis of novel molecular scaffolds is demonstrated. Twenty two scaffolds were prepared from just four α-amino acid-derived building blocks and a toolkit of six connective reactions.
Adam Nelson +27 more
core +2 more sources
Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance
This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini +3 more
wiley +1 more source
ABSTRACT Formaldehyde and its releasers are common preservatives and potent sensitizers. This meta‐analysis aimed to estimate the prevalence of formaldehyde contact allergy and allergy to its five most common releasers among dermatitis patients. Two authors independently searched PubMed, Embase, and Web of Science from inception to 30th September 2025.
Kian Karimian +5 more
wiley +1 more source
Tautomeric Equilibria Studies by Mass Spectrometry [PDF]
Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro +3 more
core +1 more source
The Pyroglutamate Hydantoin Rearrangement [PDF]
AbstractWhen a mixture of a pyroglutamate and an isocyanate in THF is treated with NaH, a ring transformation occurs leading to functionalised hydantoins. The novel reaction involves a ring‐closing ring‐opening sequence providing a new and straightforward access to an interesting class of heterocyclic compounds.
Nicolai Dieltiens +6 more
openaire +1 more source
Dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives were prepared by successive N3- and N1-alkylation of hydantoins, followed by regioselective thionation and subsequent cyclization under mild conditions.
Nikolay T. Tzvetkov +2 more
doaj +1 more source
Hydantoins and their derivatives constitute a group of pharmaceutical compounds with anticonvulsant and antiarrhythmic properties, and are also used against diabetes. N-3 and C-5 substituted imidazolidines are examples of such products.
José Alixandre de Sousa Luis +7 more
doaj +1 more source

