Results 51 to 60 of about 1,978 (203)
Contact Dermatitis, EarlyView.ABSTRACT Formaldehyde and its releasers are common preservatives and potent sensitizers. This meta‐analysis aimed to estimate the prevalence of formaldehyde contact allergy and allergy to its five most common releasers among dermatitis patients. Two authors independently searched PubMed, Embase, and Web of Science from inception to 30th September 2025.
Kian Karimian +5 more
wiley +1 more source
Making sense of chemical space network shows signs of criticality
Scientific Reports, 2023 Chemical space modelling has great importance in unveiling and visualising latent information, which is critical in predictive toxicology related to drug discovery process.
Nicola Amoroso +9 more
doaj +1 more source
Palladium Catalyzed C‑Arylation of Amino Acid Derived Hydantoins
, 2015 Palladium(II) trifluoroacetate (5 mol %) catalyzes the C-arylation of N,N-disubstituted hydantoins by aryl iodides in good yield. The reaction proceeds through base-promoted enolization of the amino acid derived hydantoins, and the resulting 5,5 ...
Josep Mas Roselló (1555168) +9 more
core +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
, 2016 The eco-friendly preparation of 5- and 5,5-disubstituted hydantoins from various amino ester hydrochlorides and potassium cyanate in a planetary ball-mill is described.
Jean Martinez (150107) +6 more
core +2 more sources
The synthesis of 5-substituted hydantoins
, 2008 The Bucherer-Bergs reaction is a classical multi-component reaction that yields hydantoins, which can be hydrolysed to afford α-amino acids. Hydantoins have many uses in modern organic synthesis, and this moiety has been included in a number of ...
Murray, Ross George
core +1 more source
Regioselective multicomponent sequential synthesis of hydantoins
, 2012 The development of new practical and green methods for the synthesis of small heterocycles is an attractive area of research due to the well-known potential of heterocyclic small molecule scaffolds in the drug discovery process.
A. Volonterio +5 more
core +1 more source
Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman +7 more
wiley +1 more source
An Efficient Synthesis of Hydantoins via Sustainable Integration of Coupled Domino Processes
, 2016 A highly efficient synthesis of hydantoins has been developed from simple and commercially available 1,3-dicarbonyl compounds, ureas, and methyl ketones or terminal aryl alkenes.
Li-Ping Cao (194542) +8 more
core +2 more sources
Advanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.Herein, an organocatalytic asymmetric synthesis of dihydroquinoline/hydantoin hybrids is described. The synthetic protocol involves a tandem reaction comprising a phosphoric acid–catalyzed initial Povarov dimerization of in situ generated imine/enamine mixtures under tautomeric equilibrium, followed by a Urech–Read reaction of the 1,2‐dihydroquinoline ...
Zuriñe Serna‐Burgos +5 more
wiley +1 more source