Results 51 to 60 of about 2,171 (198)

Cu-catalyzed N‑3-Arylation of Hydantoins Using Diaryliodonium Salts

, 2020
A general Cu-catalyzed, regioselective method for the N-3-arylation of hydantoins is described. The protocol utilizes aryl­(trimethoxyphenyl)­iodonium tosylate as the arylating agent in the presence of triethylamine and a catalytic amount of a simple Cu ...
Alexander H. Sandtorv, David S. Wragg (1368087), Alexander H. Sandtorv (3610013), Linn Neerbye Berntsen, David S. Wragg, Linn Neerbye Berntsen (8607585), Ainara Nova (1661968), Ainara Nova   +7 more
core   +1 more source

Making sense of chemical space network shows signs of criticality

Scientific Reports, 2023
Chemical space modelling has great importance in unveiling and visualising latent information, which is critical in predictive toxicology related to drug discovery process.
Nicola Amoroso, Nicola Gambacorta, Fabrizio Mastrolorito, Maria Vittoria Togo, Daniela Trisciuzzi, Alfonso Monaco, Ester Pantaleo, Cosimo Damiano Altomare, Fulvio Ciriaco, Orazio Nicolotti   +9 more
doaj   +1 more source

Hybrid Emulsion‐Dispersion (HED) Polymerization Enables One‐Pot Synthesis of Functional Janus Nanoparticles

Small, EarlyView.
A hybrid emulsion‐dispersion (HED) polymerization strategy enables one‐pot synthesis of functional Janus nanoparticles without seed preparation or multistep processing. Controlled morphology and surface stratification produce rechargeable antimicrobial coatings with durable activity. HED provides a simple and scalable route toward functional asymmetric
Utsav Kumar Dey, Ricardo Ortega, Serkan Demirci, Yifan Li, Fei Liu, Zhengtao Yang, Tiago Twedt, Prabhdeesh Singh, Juan‐Carlos Mora‐Diaz, Nubia Resende De Macedo, Luis G. Gimenez‐Lirola, Shan Jiang   +11 more
wiley   +1 more source

Palladium Catalyzed C‑Arylation of Amino Acid Derived Hydantoins

, 2015
Palladium­(II) trifluoroacetate (5 mol %) catalyzes the C-arylation of N,N-disubstituted hydantoins by aryl iodides in good yield. The reaction proceeds through base-promoted enolization of the amino acid derived hydantoins, and the resulting 5,5 ...
Josep Mas Roselló (1555168), Simon Hardy (1555174), Fernández-Nieto, Fernando, Mas Roselló, Josep, Clayden, Jonathan, Simone Lenoir (1555177), Hardy, Simon, Fernando Fernández-Nieto (1555171), Jonathan Clayden (1359093), Lenoir, Simone   +9 more
core   +1 more source

The Aminobarbituric Acid−Hydantoin Rearrangement [PDF]

The Journal of Organic Chemistry, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Manuela, Meusel, Agnieszka, Ambrozak, Thomas K, Hecker, Michael, Gütschow   +3 more
openaire   +2 more sources

Enhanced through‐bond energy transfer‐based bioorthogonal probe enables catalytic‐amplified and sensitive detection of microRNA‐21 for clinical lung cancer diagnosis

Smart Molecules, EarlyView.
Inverse Diels‐Alder Cycloaddition Reaction was developed for ultrasensitive miR‐21 detection. Based on the enhanced Through‐Bond Energy Transfer and catalytic amplification, it shows a detection limit of 3.58 × 10−18 M and 100 aM–100 nM linear range. It enables high‐contrast cell/tissue imaging and distinguishes lung cancer patients in serum, promising
Yikun Li, Fuping Han, Haiqiao Huang, Danhong Zhou, Saran Long, Wen Sun, Jianjun Du, Jiangli Fan, Jing Ning, Chong Peng, Xiaojun Peng   +10 more
wiley   +1 more source

Fluorous Synthesis of Hydantoins and Thiohydantoins. [PDF]

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Wei, Zhang, Yimin, Lu
openaire   +2 more sources

Methylchloroisothiazolinone and Methylisothiazolinone 10 Years After Regulation: A Case Story of Liquid Soaps and Shampoos

Contact Dermatitis, Volume 95, Issue 4, Page 405-412, October 2026.
MCI/MI and MI contact allergy remain persistent. In this analysis of the Danish market, 257 products containing MCI/MI or MI were identified, and 30 products were analysed. Two exceeded regulatory limits, while most complied, suggesting current limits may require further investigation. Created in BioRender. Pedersen, M. K.
Mathias Krogh Pedersen, Jakob Ferløv Baselius Schwensen, Jose Hernán Alfonso, Christel Søgaard Kirkeby, Stine Müller, Steen Mollerup, Gianluca Selvestrel, Christina Rudén, Martin F. Wilks, Jeanne Duus Johansen   +9 more
wiley   +1 more source

Regioselective multicomponent sequential synthesis of hydantoins

, 2012
The development of new practical and green methods for the synthesis of small heterocycles is an attractive area of research due to the well-known potential of heterocyclic small molecule scaffolds in the drug discovery process.
A. Volonterio, T. Marcelli, F. Olimpieri, M. C. Bellucci, M.C. Bellucci, VOLONTERIO, ALESSANDRO   +5 more
core   +1 more source

Poly(ethylene glycol)s as grinding additives in the mechanochemical preparation of highly functionalized 3,5-disubstituted hydantoins

Beilstein Journal of Organic Chemistry, 2017
The mechanochemical preparation of highly functionalized 3,5-disubstituted hydantoins was investigated in the presence of various poly(ethylene) glycols (PEGs), as safe grinding assisting agents (liquid-assisted grinding, LAG).
Andrea Mascitti, Massimiliano Lupacchini, Ruben Guerra, Ilya Taydakov, Lucia Tonucci, Nicola d’Alessandro, Frederic Lamaty, Jean Martinez, Evelina Colacino   +8 more
doaj   +1 more source