Results 51 to 60 of about 3,541 (213)
ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Molecular mechanism of ligand recognition by membrane transport protein, Mhp1 [PDF]
, 2014 The hydantoin transporter Mhp1 is a sodium-coupled secondary active transport protein of the nucleobase-cation-symport family and a member of the widespread 5-helix inverted repeat superfamily of transporters.
A Peter Johnson +17 more
core +4 more sources
Journal of Intellectual Disability Research, Volume 70, Issue 6, Page 561-578, June 2026.ABSTRACT Background Family members' involvement in the care for their relative often continues after their relative has moved out of the family home. However, little is known about the needs of family members when collaborating specifically with support staff caring for their relative.
Frances R. Vereijken +3 more
wiley +1 more source
New Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria [PDF]
, 2017 Multidrug resistance (MDR) has appeared in response to selective pressures resulting from the incorrect use of antibiotics and other antimicrobials.
Amaral, Leonard +3 more
core +5 more sources
Making sense of chemical space network shows signs of criticality
Scientific Reports, 2023 Chemical space modelling has great importance in unveiling and visualising latent information, which is critical in predictive toxicology related to drug discovery process.
Nicola Amoroso +9 more
doaj +1 more source
Contact Dermatitis, Volume 94, Issue 5, Page 524-530, May 2026.Most solid shampoos (68.6%) did not contain preservatives according to Annex V of the EU Cosmetics Regulation (EC 1223/2009), while all liquid shampoos did. The number of preservatives used was significantly greater in liquid shampoos. ABSTRACT Background Hairdressers are frequently exposed to shampoos, both from neat liquid products and dilutions ...
Wolfgang Uter +7 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.Various substituted chromane‐2‐carboxamides were successfully deracemized by employing a chiral benzophenone (BP, 10 mol%) as photocatalyst and an achiral thiol as additive (20 mol%). The method was applied to the concise enantioselective synthesis of five active pharmaceutical ingredients.
Biki Ghosh +5 more
wiley +2 more sources
Sinteza, spektroskopska karakterizacija i ab initio istraživanje tioanaloga spirohidantoina [PDF]
, 2005 Dithioanalogues of cycloalkanespiro-5-hydantoins were prepared by reaction of the respective spirohydantoins with Lawesson’s reagent or P4S10. Cycloalkanespiro-5-(2-thiohydantoins) and cycloalkanespiro-5-(4-hydantoins) were also synthesized from ...
Galya Ivanova +5 more
core +1 more source
The Aminobarbituric Acid−Hydantoin Rearrangement [PDF]
The Journal of Organic Chemistry, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Manuela, Meusel +3 more
openaire +2 more sources
Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis [PDF]
, 1990 The use of the 1-benzotriazolylearbonyl-(Bte)-group as an N-protecting and N-activating group in the synthesis of peptides was investigated. Removal of the Btc group from N-Btc-amino acids, their esters and amides under acidic conditions is possible, but
Butula, Ivan +2 more
core +3 more sources