Results 61 to 70 of about 2,171 (198)

Rechargeable N ‐Halamine Functionalized Ultra‐Thin PES Ultrafiltration Membranes

Journal of Polymer Science, Volume 64, Issue 18, Page 3986-4000, 15 September 2026.
An automated 3D printer‐assisted casting platform is utilized to fabricate ultra‐thin polyethersulfone membranes with precise structural control. The integration of a custom‐synthesized, regenerable N‐halamine homopolymer imparts superior, cyclic antifouling resistance and rapid, broad‐spectrum antibacterial efficacy.
Ahmet Aydın, Fatma Demirci, Hasan Basri Kocer   +2 more
wiley   +1 more source

Synthesis and Biological Evaluation of 1,3,8-Triazaspiro[4.5]decane-2,4-dione Derivatives as Myelostimulators

Journal of Chemistry, 2018
Spiroconnected N-alkoxyalkylpiperidine hydantoins were obtained via the Strecker reaction of cyanohydrin with ammonium carbonate. 1,3,8-Triazaspiro[4.5]decane-2,4-diones have shown the myelostimulating activity in the artificially induced (with ...
Valentina Yu, Assel Ten, Lyailya Baktybayeva, Indira Sagatbekova, Kaldybay Praliyev, Darya Zolotareva, Tulegen Seilkhanov, Alexey Zazybin   +7 more
doaj   +1 more source

Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande, Rubén Solorzano‐Rodriguez, Maria Carta, Francesco Delogu, Joris Vezzani, Allan Niidu, Evelina Colacino   +6 more
wiley   +1 more source

Sequential Ugi reaction/base-induced ring closing/IAAC protocol toward triazolobenzodiazepine-fused diketopiperazines and hydantoins

Beilstein Journal of Organic Chemistry, 2018
A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary ...
Robby Vroemans, Fante Bamba, Jonas Winters, Joice Thomas, Jeroen Jacobs, Luc Van Meervelt, Jubi John, Wim Dehaen   +7 more
doaj   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Integrative In Silico Profiling of Major Phytochemicals From a Sclerocarya birrea–Nauclea latifolia–Piper longum Mixture: Docking, Molecular Dynamics, ADMET, and Ligand‐Based Target Prediction on Shared Pathways in Type 2 Diabetes Mellitus and Alzheimer's Disease

ChemistryOpen, Volume 15, Issue 9, September 2026.
Which major phytochemical from the Sclerocarya birrea–Nauclea latifolia–Piper longum mixture engages shared targets across the T2DM–AD axis? Integrated docking, triplicate 100‐ns molecular dynamics, post‐MD MM‐GBSA, and ADMET/target prediction prioritize QR‐PME, which forms stable GSK3β and TACE complexes with binding energy estimates comparable to ...
Jean Philippe Djientcheu Tientcheu, Erman Salih İstifli   +1 more
wiley   +1 more source

An Efficient Synthesis of Hydantoins via Sustainable Integration of Coupled Domino Processes

, 2016
A highly efficient synthesis of hydantoins has been developed from simple and commercially available 1,3-dicarbonyl compounds, ureas, and methyl ketones or terminal aryl alkenes.
Li-Ping Cao (194542), An-Xin Wu (1393744), Yan Yang (33204), Cong Deng (2075887), Wen-Ming Shu (1433695), Yan-Dong Wu (1393741), Neng-Fang She (2265442), Meng Gao (399324), Dong-Xue Zhang (1997926)   +8 more
core   +2 more sources

Mechanochemical Preparation of Hydantoins from Amino Esters: Application to the Synthesis of the Antiepileptic Drug Phenytoin

, 2016
The eco-friendly preparation of 5- and 5,5-disubstituted hydantoins from various amino ester hydrochlorides and potassium cyanate in a planetary ball-mill is described.
Jean Martinez (150107), Evelina Colacino (1498090), Benjamin Reneaud (1724656), Jean-Marc Campagne (1724650), Laure Konnert (1498087), Frédéric Lamaty (1498096), Renata Marcia de Figueiredo (1724653)   +6 more
core   +2 more sources

From o‐Phenylenediamine to Flavin Derivatives: A Potential Prebiotic Carbon Skeleton Expansion With Formaldehyde, Cyanide, and CO2

Advanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
A Strecker‐type reaction of aromatic ortho‐diamines with various aldehydes and cyanide assembles the bicyclic amidine core of flavin‐derived heterocycles under mild conditions. Subsequent oxidation, radical or photochemical cyanation, carboxylation with CO2, and CO2‐mediated cyclization build the three‐ring alloxazine scaffold. This sequence provides a
Christian Held, Rodrigo José da Silva Lima, Ji‐Woong Lee   +2 more
wiley   +1 more source

Synthesis and characterization of amino acid-derived hydantoins

, 2021
The Urech hydantoin synthesis is the chemical reaction of amino acids with potassium cyanate and hydrochloric acid, which allows access to hydantoins and its derivatives.
Chin, Ee-Zhen, Tan, Siow-Ping, Liew, Sook-Yee, Kurz, Thomas   +3 more
core