Results 31 to 40 of about 1,234 (170)

Pulsed Fe Electro-Oxidation for Catalytic Synthesis of Hydantoin Derivatives

open access: yesInternational Journal of Electrochemical Science, 2016
This paper presents an original and practical organic electrochemical/chemical (EC/C) synthesis to prepare hydantoin derivatives from N-Alkyl-piperidin-4-ones.
S. Santiago-Ruiz   +3 more
doaj   +1 more source

Synthesis, structure and biological properties of active spirohydantoin derivatives [PDF]

open access: yesHemijska Industrija, 2016
Spirohidantoins represent an pharmacologically important class of heterocycles since many derivatives have been recognized that display interesting activities against a wide range of biological targets.
Lazić Anita M.   +4 more
doaj   +1 more source

Biologically Oriented Hybrids of Indole and Hydantoin Derivatives

open access: yesMolecules, 2023
Indoles and hydantoins are important heterocycles scaffolds which present in numerous bioactive compounds which possess various biological activities. Moreover, they are essential building blocks in organic synthesis, particularly for the preparation of ...
Konstantin A. Kochetkov   +2 more
doaj   +1 more source

Lipophilicity assessment of some 5,5-disubstituted hydantoins by the means of reversed phase liquid chromatography [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2013
The retention of some 5,5-disubstituted hydantoins was investigated by reversed phase high performance thin-layer chromatography (RP HPTLC) and reversed phase high-pressure liquid chromatography (RP HPLC).
Despotović Vesna   +4 more
doaj   +1 more source

New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Oxidative damage to DNA, if not repaired, can be both miscoding and blocking. These genetic alterations can lead to mutations and/or cell death, which in turn cause cancer and aging.
Modesto Redrejo-Rodríguez   +6 more
doaj   +1 more source

Synthesis and investigation of solvent effects on the ultraviolet absorption spectra of 1, 3-bis-substituted-5, 5-dimethylhydantoins [PDF]

open access: yesJournal of the Serbian Chemical Society, 2003
A series of 1,3-bis-substituted-5,5-dimethylhydantoins was synthesized using the reaction of 5,5-dimethylhydantoin with the corresponding alkyl halide in the presence of trimethylamine as catalyst and sodium hydroxide, according to a modified literature ...
Ušćumlić Gordana S.   +2 more
doaj   +3 more sources

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

open access: yesAngewandte Chemie International Edition, EarlyView.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee   +5 more
wiley   +1 more source

Regioselective synthesis of 7,8-dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives: A new drug-like heterocyclic scaffold

open access: yesBeilstein Journal of Organic Chemistry, 2012
Dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives were prepared by successive N3- and N1-alkylation of hydantoins, followed by regioselective thionation and subsequent cyclization under mild conditions.
Nikolay T. Tzvetkov   +2 more
doaj   +1 more source

Synthesis of New Imidazolidin-2,4-dione and 2-Thioxoimidazolidin-4-ones via C-Phenylglycine Derivatives

open access: yesMolecules, 2009
Hydantoins and their derivatives constitute a group of pharmaceutical compounds with anticonvulsant and antiarrhythmic properties, and are also used against diabetes. N-3 and C-5 substituted imidazolidines are examples of such products.
José Alixandre de Sousa Luis   +7 more
doaj   +1 more source

Machine Learning Paradigm for Advanced Battery Electrolyte Development

open access: yesCarbon Energy, EarlyView.
Electrolyte materials determine ion transport kinetics within the bulk and interphases, ultimately influencing the performance of battery systems. As data‐driven paradigms increasingly reshape materials discovery, this review provides an application‐oriented exploration of the intersection between machine learning and electrolyte science. By evaluating
Chang Su   +4 more
wiley   +1 more source

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