Hydantoins: Synthesis, properties and anticonvulsant activity [PDF]
Hemijska Industrija, 2009 Hydantoin is a five-membered cyclic ureide that is present in numerous biologically active compounds including antiarrhytmics, anticonvulsants and antitumor agents. This paper describes different ways of synthesis of hydantoin-derivatives, their physical
Trišović Nemanja P. +2 more
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Acute Hepatic Porphyrias: Review and Recent Progress. [PDF]
, 2019 The acute hepatic porphyrias (AHPs) are a group of four inherited diseases of heme biosynthesis that present with episodic, acute neurovisceral symptoms.
Andant +40 more
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Pulsed Fe Electro-Oxidation for Catalytic Synthesis of Hydantoin Derivatives
International Journal of Electrochemical Science, 2016 This paper presents an original and practical organic electrochemical/chemical (EC/C) synthesis to prepare hydantoin derivatives from N-Alkyl-piperidin-4-ones.
S. Santiago-Ruiz +3 more
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Synthesis, structure and biological properties of active spirohydantoin derivatives [PDF]
Hemijska Industrija, 2016 Spirohidantoins represent an pharmacologically important class of heterocycles since many derivatives have been recognized that display interesting activities against a wide range of biological targets.
Lazić Anita M. +4 more
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Biologically Oriented Hybrids of Indole and Hydantoin Derivatives
Molecules, 2023 Indoles and hydantoins are important heterocycles scaffolds which present in numerous bioactive compounds which possess various biological activities. Moreover, they are essential building blocks in organic synthesis, particularly for the preparation of ...
Konstantin A. Kochetkov +2 more
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Immunological Abnormalities and Hydantoins [PDF]
BMJ, 1972 Various immunological features were measured in 20 patients with epilepsy who had received prolonged treatment with hydantoins. Immunoglobulin A (IgA) was shown to be absent or low in five patients, beta(1)C/A was low in 10 patients. Five patients showed negative reactions to skin tests, and two could not be sensitized to dinitrochlorobenzene.
P J, Grob, G E, Herold
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Complementary regioselectivity in the synthesis of iminohydantoins: remarkable effect of amide substitution on the cyclization [PDF]
, 2013 Complementary regioselective synthesis of iminohydantoins from isocyanoacetamides controlled by the substituent on the amide group has been described.
García Valverde, María +5 more
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Lipophilicity assessment of some 5,5-disubstituted hydantoins by the means of reversed phase liquid chromatography [PDF]
Chemical Industry and Chemical Engineering Quarterly, 2013 The retention of some 5,5-disubstituted hydantoins was investigated by reversed phase high performance thin-layer chromatography (RP HPTLC) and reversed phase high-pressure liquid chromatography (RP HPLC).
Despotović Vesna +4 more
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Electronic effects in the cyclocondensation of benzil [PDF]
, 2010 Electronic effects are important directing forces in the course of chem. reactions. Small differences in these effects can bring about considerable changes in the results of very similar reactions.
Nagendrappa, G.
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New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. [PDF]
PLoS ONE, 2011 BACKGROUND: Oxidative damage to DNA, if not repaired, can be both miscoding and blocking. These genetic alterations can lead to mutations and/or cell death, which in turn cause cancer and aging.
Modesto Redrejo-Rodríguez +6 more
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