Results 31 to 40 of about 1,978 (203)
The Pyroglutamate Hydantoin Rearrangement [PDF]
European Journal of Organic Chemistry, 2006 Abstract When a mixture of a pyroglutamate and an isocyanate in THF is treated with NaH, a ring transformation occurs leading to functionalised hydantoins. The novel reaction involves a ring‐closing ring‐opening sequence providing a new and straightforward access to an interesting class of heterocyclic compounds. Furthermore, starting
Nicolai Dieltiens +6 more
openaire +1 more source
1-Methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione
Molbank, 2021 A simple, fast and cost-effective three-step synthesis of 1-methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione has been developed. The reactions described herein proceed readily, with high yields and no further purification.
Vasiliki Pardali +3 more
doaj +1 more source
Hydantoins: Synthesis, properties and anticonvulsant activity [PDF]
Hemijska Industrija, 2009 Hydantoin is a five-membered cyclic ureide that is present in numerous biologically active compounds including antiarrhytmics, anticonvulsants and antitumor agents. This paper describes different ways of synthesis of hydantoin-derivatives, their physical
Trišović Nemanja P. +2 more
doaj +1 more source
Cu-catalyzed N-3-Arylation of Hydantoins Using Diaryliodonium Salts
, 2020 A general Cu-catalyzed, regioselective method for the N-3-arylation of hydantoins is described. The protocol utilizes aryl(trimethoxyphenyl)iodonium tosylate as the arylating agent in the presence of triethylamine and a catalytic amount of a simple Cu ...
Sandtorv, Alexander Harald +3 more
core +1 more source
Pulsed Fe Electro-Oxidation for Catalytic Synthesis of Hydantoin Derivatives
International Journal of Electrochemical Science, 2016 This paper presents an original and practical organic electrochemical/chemical (EC/C) synthesis to prepare hydantoin derivatives from N-Alkyl-piperidin-4-ones.
S. Santiago-Ruiz +3 more
doaj +1 more source
Synthesis, structure and biological properties of active spirohydantoin derivatives [PDF]
Hemijska Industrija, 2016 Spirohidantoins represent an pharmacologically important class of heterocycles since many derivatives have been recognized that display interesting activities against a wide range of biological targets.
Lazić Anita M. +4 more
doaj +1 more source
Biologically Oriented Hybrids of Indole and Hydantoin Derivatives
Molecules, 2023 Indoles and hydantoins are important heterocycles scaffolds which present in numerous bioactive compounds which possess various biological activities. Moreover, they are essential building blocks in organic synthesis, particularly for the preparation of ...
Konstantin A. Kochetkov +2 more
doaj +1 more source
Base-Promoted Solid-Phase Synthesis of Substituted Hydantoins and Thiohydantoins
, 2016 Base-Promoted Solid-Phase Synthesis of Substituted Hydantoins and ...
Jay Matthews (3040941) +1 more
core +2 more sources
Lipophilicity assessment of some 5,5-disubstituted hydantoins by the means of reversed phase liquid chromatography [PDF]
Chemical Industry and Chemical Engineering Quarterly, 2013 The retention of some 5,5-disubstituted hydantoins was investigated by reversed phase high performance thin-layer chromatography (RP HPTLC) and reversed phase high-pressure liquid chromatography (RP HPLC).
Despotović Vesna +4 more
doaj +1 more source