Pulsed Fe Electro-Oxidation for Catalytic Synthesis of Hydantoin Derivatives
International Journal of Electrochemical Science, 2016 This paper presents an original and practical organic electrochemical/chemical (EC/C) synthesis to prepare hydantoin derivatives from N-Alkyl-piperidin-4-ones.
S. Santiago-Ruiz +3 more
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1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis [PDF]
, 2016 Asymmetric catalysis represents a very powerful tool for the synthesis of enantiopure compounds. In this context the main focus has been directed not only to the search for new efficient chiral catalysts, but also to the development of efficient ...
Mielgo Vicente, María Antonia +1 more
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Synthesis, structure and biological properties of active spirohydantoin derivatives [PDF]
Hemijska Industrija, 2016 Spirohidantoins represent an pharmacologically important class of heterocycles since many derivatives have been recognized that display interesting activities against a wide range of biological targets.
Lazić Anita M. +4 more
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Biologically Oriented Hybrids of Indole and Hydantoin Derivatives
Molecules, 2023 Indoles and hydantoins are important heterocycles scaffolds which present in numerous bioactive compounds which possess various biological activities. Moreover, they are essential building blocks in organic synthesis, particularly for the preparation of ...
Konstantin A. Kochetkov +2 more
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Lipophilicity assessment of some 5,5-disubstituted hydantoins by the means of reversed phase liquid chromatography [PDF]
Chemical Industry and Chemical Engineering Quarterly, 2013 The retention of some 5,5-disubstituted hydantoins was investigated by reversed phase high performance thin-layer chromatography (RP HPTLC) and reversed phase high-pressure liquid chromatography (RP HPLC).
Despotović Vesna +4 more
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Immunological Abnormalities and Hydantoins [PDF]
BMJ, 1972 Various immunological features were measured in 20 patients with epilepsy who had received prolonged treatment with hydantoins. Immunoglobulin A (IgA) was shown to be absent or low in five patients, beta(1)C/A was low in 10 patients. Five patients showed negative reactions to skin tests, and two could not be sensitized to dinitrochlorobenzene.
P J, Grob, G E, Herold
openaire +2 more sources
Molecular mechanism of ligand recognition by membrane transport protein, Mhp1 [PDF]
, 2014 The hydantoin transporter Mhp1 is a sodium-coupled secondary active transport protein of the nucleobase-cation-symport family and a member of the widespread 5-helix inverted repeat superfamily of transporters.
A Peter Johnson +17 more
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Recent Applications of Hydantoins in Drug Discovery: Updates (2019~Present)
MoleculesHydantoins, exemplified by the imidazolidine-2,4-dione core, are privileged scaffolds in medicinal chemistry due to their compact structure, versatile hydrogen-bonding capacity, ability to fine-tune physicochemical properties for drug-like molecules, and
Jyoti Dnyaneshwar Palkhede +3 more
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New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. [PDF]
PLoS ONE, 2011 BACKGROUND: Oxidative damage to DNA, if not repaired, can be both miscoding and blocking. These genetic alterations can lead to mutations and/or cell death, which in turn cause cancer and aging.
Modesto Redrejo-Rodríguez +6 more
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Synthesis and investigation of solvent effects on the ultraviolet absorption spectra of 1, 3-bis-substituted-5, 5-dimethylhydantoins [PDF]
Journal of the Serbian Chemical Society, 2003 A series of 1,3-bis-substituted-5,5-dimethylhydantoins was synthesized using the reaction of 5,5-dimethylhydantoin with the corresponding alkyl halide in the presence of trimethylamine as catalyst and sodium hydroxide, according to a modified literature ...
Ušćumlić Gordana S. +2 more
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