Results 51 to 60 of about 18,659 (282)

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

Pharmacological aspects of hydrazides and hydrazide derivatives

Health Promotion & Physical Activity, 2017
Intense search for new antimicrobials, including anti-tuberculosis drugs, is dictated by the phenomenon of bacterial multidrug resistance. Hydrazides are considered the key intermediate and valuable starting material for some novel biologically active compounds.
openaire   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

N′-[(E)-2-Hydroxybenzylidene]-2-(6-methoxynaphthalen-2-yl)propanohydrazide: a redetermination

IUCrData, 2016
The structure of the title compound, C21H20N2O3, was originally determined at ambient temperature [Wu et al. (2007). Inorg. Chim. Acta, 360, 3069–3074].
Shaaban K. Mohamed, Joel T. Mague, Mehmet Akkurt, Alaa F. Mohamed, Mustafa R. Albayati   +4 more
doaj   +1 more source

Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes

, 2014
The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years.
Aebersold, R., Frydman, J., Förster, F., Joachimiak, L., Leitner, A., Unverdorben, P., Walzthoeni, T.   +6 more
core   +1 more source

Selective Extraction and in Situ Reduction of Precious Metal Salts from Model Waste to Generate Hybrid Gels with Embedded Electrocatalytic Nanoparticles [PDF]

, 2016
A hydrogel based on 1,3:2,4-dibenzylidenesorbitol (DBS), modified with acyl hydrazides which extracts gold/silver salts from model waste is reported, with preferential uptake of precious heavy metals over other common metals.
Adhikari, Amabilino, Argueta-Robles, Babu, Babu, Banerjee, Bhattacharya, Canevet, Carter, Chakraborty, Coates, Cornwell, Cornwell, Das, Dawn, Debnath, Dodson, Dutta, Dutta, García, Green, Hao, Hirst, Howe, Kar, Kimura, King, Knerr, Kumar, Kuwahara, Li, Lv, Malathi, Mitra, Mpinga, Nahir, Okesola, Okesola, Page, Park, Puigmartí-Luis, Puigmartí-Luis, Ray, Rodríguez-Llansola, Ronkainen, Roy, Roy, Samanta, Samanta, Sengupta, Shen, Srinivasan, Steed, Sukul, Sun, Taboada, Terech, van Herrikhuyzen, Vemula, Vemula, Vyas, Wang, Weiss, Westerhoff, Wood, Zhao   +65 more
core   +1 more source

NIR Light‐Driven Photocatalytic Antibacterial Hydrogels for Synergistic MRSA Biofilm Eradication and Wound Regeneration

Advanced Science, EarlyView.
The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo, Yujia Wei, Meng Pan, Wen Chen, Yun Yang, Kang Li, Xicheng Li, Jianan Li, Qingya Liu, Hanzi Deng, Mei Zhu, Zhenpeng Zhang, Zhaolin Xiao, Zhiyong Qian   +13 more
wiley   +1 more source

Aggregation‐Induced Resonance Energy Transfer in Polymer Dots to Boost Electrochemiluminescence Performance for Bioimaging of Glycan on Cells

Advanced Science, EarlyView.
This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang, Mengjiao Li, Yiran Li, Xiangfu Hu, Chunlan Li, Ningning Wang, Huangxian Ju   +6 more
wiley   +1 more source

Improved Protocol Toward 1,3,4-Oxadiazole-2(3H)-thiones and Scale-up Synthesis in the Presence of SDS as a Micelle Promoted Catalyst

Acta Chimica Slovenica, 2015
Convenient procedure for in situ cyclization of hydrazinecarbodithioate potassium salts to 1,3,4-oxadiazole-2(3H)-thiones under normal phase micellar media catalysis promoted by sodium dodecyl sulfate (SDS) as an anionic surfactant is reported.
Ayhan YILDIRIM
doaj   +1 more source