Results 171 to 180 of about 59,471 (323)

Three Cu (II)-hydrazone complexes: synthesis, physicochemical characteristics, stability, thermal analysis, and investigation of metal and iodine absorption [PDF]

, 2023
Ahmed A. Alzharani
openalex   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source

Surface‐Decoupled Altitudinal and Azimuthal Triptycene‐Fused Tetrapodal Molecular Motors

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Two tetrapodal triptycene‐based light‐driven molecular motors with precisely oriented rotation axes—parallel or perpendicular to a gold surface—achieve full 360° rotation in both solution and as monolayers. The design minimizes surface quenching, enabling functional integration into surface‐mounted nanomachines.
Kateřina Bezděková, Lukáš Severa, Eva Kaletová, Katarina Majerová Varga, Milan Mašát, Liang‐Ting Wu, Jyh‐Chiang Jiang, Ivana Císařová, Jiří Kaleta   +8 more
wiley   +2 more sources

An Overview of Liquid Chromatography–Mass Spectrometry (LC–MS) Methods for the Quantification of Antibody‐Drug Conjugates

Biomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT Antibody‐drug conjugates (ADCs) are innovative drugs composed of cytotoxic molecules (payload) linked to antibodies, that selectively target and kill cancer cells upon internalization. In vivo, ADCs exist as intact molecules, naked antibodies, or released, unconjugated (linker‐)payload.
Pauline L. M. Buitelaar, Hilde Rosing, Jos H. Beijnen, Neeltje Steeghs, Alwin D. R. Huitema   +4 more
wiley   +1 more source

Triply Responsive Control of Ion Transport with an Artificial Channel Creates a Switchable AND to OR Logic Gate

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
We report a triply responsive artificial ion channel, showing tuneable activity, and responsive to three distinct stimuli ‐ light, pH, and ligand – which we use to formulate an AND to OR switchable molecular logic gate. Abstract Ion channels are ubiquitous in Nature, performing complex and essential tasks in our bodies. Synthetic chemists have begun to
Javid Ahmad Malla, Kharina J. Fenton, Adinarayana Bellamkonda, Samuel I. Fidler, Mark I. Wallace, Charlie T. McTernan   +5 more
wiley   +2 more sources

A general aqueous synthetic strategy towards 1-benzylTHIQs enabled by umpolung hydrazone. [PDF]

Chem Sci
Kaur M, Chen EFW, Salgado JM, Cheng R, Li CJ.   +4 more
europepmc   +1 more source

Synthesis and crystal structure of [Co(L)(NO₂)₃]H₂O (L= piridoxylene Girar-T hydrazone) [PDF]

, 2004
Ljiljana S. Vojinović‐Ješić, Sladjana B. Novaković, Goran A. Bogdanović, Vukadin M. Leovac, Valerija I. Češljević, Katalin Mészáros Szécsényi   +5 more
openalex   +1 more source

On‐Resin Pictet–Spengler Cyclization for 1,2,3,4‐Tetrahydro‐β‐carboline‐3‐carboxylate (Tcc) Peptide Synthesis With Acid‐Labile Functional Tolerance

Journal of Peptide Science, Volume 32, Issue 2, February 2026.
The constrained tryptophan (Trp) analog 1,2,3,4‐tetrahydro‐β‐carboline‐3‐carboxylic acid (Tcc) is used to restrict peptide conformation in structure–activity relationship studies. Although Pictet–Spengler cyclization of Trp and aldehydes with mineral acid gives Tcc analogs, such harsh conditions do not tolerate acid‐labile functionality.
Omer S. L. N'dri, Charity D. Yongo‐Luwawa, Xiaozheng Wei, Kajumee Bora Bhowal, Chitra P. Sadanandhan, Darince Truong, Ida Boccino, Will Maclean, Lylia Dif‐Yaiche, Zoé Villeneuve, William D. Lubell   +10 more
wiley   +1 more source

Ribosomal Synthesis of Topologically Defined Thioisoindole‐Bridged Bicyclic Peptides

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
A flexible in vitro translation (FIT) system‐based strategy for ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is developed. The flexizyme substrate Ac‐Ala(NtBA)Sc‐CME is efficiently incorporated into FIT to generate ribosomal peptides bearing N‐terminal Ac‐Ala(NtBA)Sc as the cyclization handle, which after mild deprotection ...
Yue Zhang, Alexander A. Vinogradov, Yin Sun, Hiroaki Suga   +3 more
wiley   +2 more sources