Results 21 to 30 of about 31,841 (197)

Synergistic drug combinations from electronic health records and gene expression. [PDF]

, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William, Daugherty, Aaron C, Desai, Manisha, Farrington, Carl, Gomez, Scarlett L, Hastie, Trevor, Kenkare, Pragati, Kurian, Allison W, Lim, Michael, Low, Yen S, Mathur, Maya, Radin, Andrew A, Schroeder, Elizabeth A, Seto, Tina, Shah, Nigam H, Sirota, Marina, Sledge, George W, Thompson, Caroline A, Weber, Susan, Yu, Peter P   +19 more
core   +2 more sources

Bioanalytical method development and validation for determination of metoprolol tartarate and hydrochlorothiazide using HPTLC in human plasma

Brazilian Journal of Pharmaceutical Sciences, 2013
A simple, sensitive, rapid and economic chromatographic method has been developed for determination of metoprolol tartarate and hydrochlorothiazide in human plasma using paracetamol as an internal standard.
Ambadas Ranganath Rote, Poonam Ramdas Sonavane   +1 more
doaj   +1 more source

Squamous cell carcinoma of the dorsal hands and feet after repeated exposure to ultraviolet nail lamps [PDF]

, 2020
Gel nails are a common artificial nail option. Ultraviolet (UV) nail lamps are commonly used to cure gel nails. Ultraviolet A radiation is a known mutagen that penetrates into the nail bed.
Curtis, Julia, Freeman, Caleb, Hull, Christopher, Sontheimer, Richard   +3 more
core  

Is early and fast blood pressure control important in hypertension management? [PDF]

, 2018
Control of blood pressure (BP) in hypertension is recognized as a key measure in the management of cardiovascular (CV) risk and is a cornerstone of preventive strategies. It is not defined, however, whether an initiation of the antihypertensive treatment
Gallo, Giovanna, Tocci, Giuliano, Volpe, Massimo   +2 more
core   +1 more source

Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]

, 1973
The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L, HALGRIMSON, CHARLES G, KATZ, FRED H, LANOIS, BERNARD, PINNGGERA, WULF, POPOVTZER, MORDECAI M, ROBINETTE, JOHN, STARZL, THOMAS E   +7 more
core   +1 more source

Comparative effects of valsartan plus cilnidipine or hydrochlorothiazide on nocturnal home blood pressure

The Journal of Clinical Hypertension, 2021
We tested our hypothesis that, in hypertensive patients with higher nocturnal home systolic blood pressure (HSBP) at baseline, a valsartan/cilnidipine (80/10 mg) combination would reduce nocturnal HSBP more markedly than a valsartan/hydrochlorothiazide ...
Takeshi Fujiwara, Satoshi Hoshide, Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario   +4 more
doaj   +1 more source

Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations

Pharmaceutics, 2021
The aim of this study was the optimization of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in terms of physicochemical and biopharmaceutical properties, to develop effective and stable aqueous liquid formulations of ...
Paola Mura, Francesca Maestrelli, Mario D’Ambrosio, Cristina Luceri, Marzia Cirri   +4 more
doaj   +1 more source

Hypertension and sudden death disparate effects of calcium entry blocker and diuretic therapy on cardiac dysrhythmias [PDF]

, 1989
This study was designed to evaluate the impact of antihypertensive therapy on cardiac dysrhythmias in 13 hypertensive patients who received calcium entry blockers and in 10 hypertensive patients who received hydrochlorothiazide.
Garavaglia, Guillermo E., Messerli, Franz H., Nunez, Boris D., Nunez, Mireya M., Schmieder, Roland E., Ventura, Hector O.   +5 more
core   +1 more source

Validated HPTLC methods for determination of some selected antihypertensive mixtures in their combined dosage forms

Bulletin of Faculty of Pharmacy Cairo University, 2014
Simple and selective HPTLC methods were developed for the simultaneous determination of the antihypertensive drugs; carvedilol and hydrochlorothiazide in their binary mixture (Mixture I) and amlodipine besylate, valsartan, and hydrochlorothiazide in ...
Rasha A. Shaalan, Tarek S. Belal, Fawzy A. El Yazbi, Sohila M. Elonsy   +3 more
doaj   +1 more source

Interaction and Compatibility Studies in the Development of Olmesartan Medoxomil and Hydrochlorothiazide Formulations under a Real Manufacturing Process

Pharmaceutics, 2022
A drug–drug and drug–excipient interactions and compatibilities study was conducted for two fixed-dose combination (FDC) products containing olmesartan medoxomil (OLM)/hydrochlorothiazide (HCT) 20/12.5 mg and OLM/HCT 40/12.5 mg during their development ...
Mac Arturo Murillo-Fernández, Ernesto Montero-Zeledón, Ariadna Abdala-Saiz, José Roberto Vega-Baudrit, Andrea Mariela Araya-Sibaja   +4 more
doaj   +1 more source