Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction
Abstract Aims Few data are available regarding the role of tricuspid annulus plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP), a measurement of right ventricular to pulmonary artery coupling, in patients with chronic heart failure and left ventricular systolic dysfunction.
Mauro Riccardi+9 more
wiley +1 more source
This paper outlines a precise, swift, and convenient spectrophotometric method based on the continuous wavelet transform methodology for the estimation of losartan potassium and hydrochlorothiazide in tablets.
Erdal Dinç, Özgür Üstündağ
doaj +1 more source
Hydrochlorothiazide Is Superior to Isradipine for Reduction of Left Ventricular Mass: Results of a Multicenter Trial fn1fn1This study was supported by an unrestricted grant from Sandoz Pharmaceuticals, East Hanover, New Jersey.fn2fn2To discuss this article on-line, visit the ACC Home Page at http://www.acc.org/membersand click on the JACC Forum [PDF]
Objectives. We sought to determine the efficacy of isradipine in reducing left ventricular (LV) mass and wall thickness in hypertensive patients.Background. LV hypertrophy on the echocardiogram is a strong predictor of cardiovascular events. Reduction of
Chase, Gary A.+6 more
core +1 more source
Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang+18 more
wiley +1 more source
Vitamin B12 protects against DNA damage induced by hydrochlorothiazide
DNA damage induced by hydrochlorothiazide was previously reported in cultured human lymphocytes. In this study, we aimed to investigate the harmful effects of hydrochlorothiazide on DNA by measuring the spontaneous frequency of sister chromatid exchanges
Karem H. Alzoubi+3 more
doaj
BackgroundThiazide and thiazide‐like diuretics are first‐line medications for treating uncomplicated hypertension. However, their use has been associated with adverse metabolic events, including hyperglycemia and incident diabetes mellitus, with ...
Sonal Singh+21 more
doaj +1 more source
Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3):a parallel-group, double-blind randomised phase 4 trial [PDF]
This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/S2213-8587(15)00377-0Background Potassium depletion by thiazide diuretics is associated with a rise in blood glucose. We assessed whether addition or
Bakris+33 more
core +8 more sources
Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley +1 more source
In this work is proposed, a simple experiment for the simultaneous determination of losartan (L) and hydrochlorothiazide (H) in synthetic and real samples by derivative spectrophotometry technique.
M. Inés Toral+3 more
doaj +1 more source
Synergistic drug combinations from electronic health records and gene expression. [PDF]
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William+19 more
core +2 more sources