Results 61 to 70 of about 96,281 (281)

Prevention of adrenal crisis: cortisol responses to major stress compared to stress dose hydrocortisone delivery in adrenal insufficiency [PDF]

, 2020
Alessandro Prete, Angela E. Taylor, Irina Bancos, David J. Smith, Mark Foster, Sibylle Köhler, Violet Fazal-Sanderson, John Komninos, Donna O’Neil, Dimitra A. Vassiliadi, Christopher J Mowatt, Radu Mihai, Joanne L. Fallowfield, Djillali Annane, Janet M. Lord, Brian Keevil, John Wass, Niki Karavitaki, Wiebke Arlt   +18 more
openalex   +1 more source

Integrin‐Piezo1 Axis Drives ECM Remodeling and Invasion of 3D Breast Epithelium

Advanced Science, EarlyView.
Mechanical stiffening of the extracellular matrix around mature mammary acini induces sequential remodeling phases. An early response disrupts the basement membrane and promotes fibronectin secretion, followed by delayed invasion with matrix reorganization and proliferation.
Kabilan Sakthivel, Anna Kotowska, Zhimeng Fan, Ellen Juel Portner, Catherine Merry, Pontus Nordenfelt, Adam Cohen Simonsen, Amanda J. Wright, Vinay S Swaminathan   +8 more
wiley   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Effect of a combination of 0.001% hydrocortisone and 0.2% hyaluronic acid on conjunctival cytology in patients with dysregulatory inflammatory changes of the conjunctiva in type 2 diabetes

Journal of Ophthalmology
Purpose. To assess and evaluate cytological changes of conjunctival epithelial cells collected by CIC and relative expression of CD15 before and after 2-month treatment with sodium hyaluronate 0.2% and 0.001% hydrocortisone among patients with ...
T. Zhmud, S. Barabino, G. Drozhzhyna
doaj   +1 more source

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

Role of very short-term intravenous hydrocortisone in reducing postdural puncture headache

Journal of Anaesthesiology Clinical Pharmacology, 2012
Objective: Headache is not an uncommon complication of spinal anesthesia. The efficacy of intravenous (IV) hydrocortisone in treating the patients with postdural puncture headache was observed in this study.
Md Rabiul Alam, Md Aminur Rahman, Reza Ershad   +2 more
doaj   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Role of hydrocortisone in prevention of pain on propofol injection

Journal of Anaesthesiology Clinical Pharmacology, 2011
Background and Objectives : Pain following intravenous injection of propofol continues to be an intriguing problem. None of the commonly used methods completely attenuate the pain. Inflammatory response to propofol contributes to the pain.
Monu Yadav, Padmaja Durga, R Gopinath
doaj   +1 more source

Genetically Engineered Light‐Responsive In Situ Hydrogels for Immunomodulation and Multimodal Therapy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Cysteine‐tagged silk‐elastin‐like proteins, a family of tri‐block chimeric proteins that consist of a photothermal agent binding motif, silk motif, and elastin motif is developed to form a responsive in situ hydrogel for late‐stage and metastatic triple‐negative breast cancer.
Xinchen Shen, Jiajia Zhang, Junhan Ou, Ziheng Bai, Tongyan Liu, Kaiyue Zhang, Kaixiang Zhu, James Q. Wang, Chaochen Wang, Qianting Zhang, Linrong Lu, Wenwen Huang   +11 more
wiley   +1 more source

Rectal Hydrocortisone [PDF]

BMJ, 1957
J D, NABARRO, A, MOXHAM, G, WALKER, J D, SLATER   +3 more
openaire   +2 more sources