Results 61 to 70 of about 113,315 (298)
Annals of Intensive Care, 2017 Background Ventilator-associated pneumonia (VAP) is a care-related event that could be promoted by immune suppression caused by critical diseases, malignancies and cancer treatments.
David Lagier +10 more
doaj +1 more source
Clinical Features of Late-Onset Circulatory Collapse in Preterm Infants [PDF]
Neonatal Medicine, 2019 Purpose This study aimed to investigate the incidence and clinical features of late-onset circulatory collapse (LCC) in preterm infants. Methods Medical records of 327 preterm infants (born before 32 gestational weeks) admitted to the neonatal intensive ...
Jin Hee Jang +4 more
doaj +1 more source
Clinical Endocrinology, 2018 There is no licensed, dose‐appropriate formulation of hydrocortisone for children with adrenal insufficiency (AI) and patients rely on compounded adult medication. The aim of this study was to evaluate the absorption, palatability and safety of Infacort®,
U. Neumann +9 more
semanticscholar +1 more source
Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee +10 more
wiley +1 more source
Drugs - Real World Outcomes, 2019 Background Pegloticase is a recombinant porcine-like uricase enzyme that is FDA-approved for the treatment of chronic refractory gout in adults. Some patients receiving pegloticase develop anti-drug antibodies, which leads to both loss of pegloticase ...
Amar Majjhoo +3 more
doaj +1 more source
Cortisone and cortisol break hydrogen-bonding rules to make a drug–prodrug solid solution
IUCrJ, 2020 Multidrug products enable more effective therapies and simpler administration regimens, provided that a stable formulation is prepared, with the desired composition.
Vivek Verma +7 more
doaj +1 more source
BMJ Paediatrics Open, 2018 Objectives Children requiring cortisol replacement therapy are often prescribed hydrocortisone doses of 2.5 mg, but as this is commercially unavailable 10 mg tablets, with functional break lines, are split commonly in an attempt to deliver the correct ...
Jude Madathilethu +5 more
semanticscholar +1 more source
Nanomaterial‐Enhanced Biosensing: Mechanisms and Emerging Applications
Advanced Healthcare Materials, EarlyView.Nanomaterial integration transforms biosensor capabilities through enhanced signal transduction, sensitivity, and selectivity. This review analyzes how nanoscale materials—from nanoparticles to nanosheets—leverage unique physicochemical properties to revolutionize electrochemical, optical, and electrical biosensing.
Younghak Cho +3 more
wiley +1 more source
Glucocorticoid susceptibility and in vivo ABCB1 activity differ in murine B cell subsets
Anais da Academia Brasileira de CiênciasGlucocorticoids are produced and released by the adrenal gland and become elevated in response to stress. Although glucocorticoids are well known for their immunosuppressive effects, less is known about their effects on B cells.
KELLI M. DA COSTA +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre +5 more
wiley +1 more source