Results 61 to 70 of about 87,509 (230)
Purpose. To assess and evaluate cytological changes of conjunctival epithelial cells collected by CIC and relative expression of CD15 before and after 2-month treatment with sodium hyaluronate 0.2% and 0.001% hydrocortisone among patients with ...
T. Zhmud, S. Barabino, G. Drozhzhyna
doaj +1 more source
Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo +6 more
wiley +1 more source
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo +13 more
wiley +1 more source
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen +11 more
wiley +1 more source
Hydrocortisone Sodium Succinate 50mg injection is widely used in perinatology wards. These wards cater to newborns (0-28 days), low birth weight (
Erza Genatrika +2 more
doaj +1 more source
Role of hydrocortisone in prevention of pain on propofol injection
Background and Objectives : Pain following intravenous injection of propofol continues to be an intriguing problem. None of the commonly used methods completely attenuate the pain. Inflammatory response to propofol contributes to the pain.
Monu Yadav, Padmaja Durga, R Gopinath
doaj +1 more source
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli +12 more
wiley +1 more source
Background: Postoperative shivering is one of the most prevalent complications that several methods were used for controlling it. This study aimed to determine the effect of two doses of intravenous hydrocortisone (1 or 2 mg/kg) on postoperative ...
Azim Honarmand +3 more
doaj
The Effect of Hydrocortisone Treatment After Day Fourteen of Life on Preventing Bronchopulmonary Dysplasia in Preterm Infants [PDF]
Background: This study aimed to evaluate whether administering low-dose hydrocortisone after the first fourteen days of life affects the incidence of bronchopulmonary dysplasia (BPD), mortality, and other short-term complications in mechanically ...
Motahhareh Talebian +3 more
doaj +1 more source

