Results 141 to 150 of about 151,216 (363)

THE PARTICULATE HYDROLASES OF MACROPHAGES [PDF]

, 1963
Zanvil A. Cohn, Edith Wiener
openalex   +1 more source

Microsomal epoxide hydrolase is not a 2-arachidonyl glycerol hydrolase [PDF]

Matters, 2016
Arand, Michael, Marowsky, Anne
openaire   +3 more sources

Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA₄ Hydrolase

ACS Medicinal Chemistry Letters, 2019
Multitarget anti-inflammatory drugs interfering with the arachidonic acid cascade exhibit superior efficacy. In this study, a prototype dual inhibitor of soluble epoxide hydrolase (sEH) and LTA4 hydrolase (LTA4H) with submicromolar activity toward both targets has been designed and synthesized.
Kerstin Hiesinger, Annika Schott, Jan S. Kramer, René Blöcher, Finja Witt, Sandra K. Wittmann, Dieter Steinhilber, Denys Pogoryelov, Jana Gerstmeier, Oliver Werz, Ewgenij Proschak   +10 more
openaire   +4 more sources

Functional characterization and structural modeling of synthetic polyester-degrading hydrolases from Thermomonospora curvata

AMB Express, 2014
Thermomonospora curvata is a thermophilic actinomycete phylogenetically related to Thermobifida fusca that produces extracellular hydrolases capable of degrading synthetic polyesters. Analysis of the genome of T.
Ren Wei, Thorsten Oeser, J. Then, Nancy Kühn, M. Barth, Juliane Schmidt, W. Zimmermann   +6 more
semanticscholar   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

Aggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang, Chengyuan Qian, Yuncong Chen, Weijiang He, Zijian Guo   +4 more
wiley   +1 more source

Glycoside hydrolase gene transcription by Alicyclobacillus acidocaldarius during growth on wheat arabinoxylan and monosaccharides: a proposed xylan hydrolysis mechanism

Biotechnology for Biofuels, 2018
Background Metabolism of carbon bound in wheat arabinoxylan (WAX) polysaccharides by bacteria requires a number of glycoside hydrolases active toward different bonds between sugars and other molecules.
Brady D. Lee, William A. Apel, Peter P. Sheridan, Linda C. DeVeaux   +3 more
doaj   +1 more source

Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14

Cell Research, 2013
Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling ...
Lihua Zhao, X. E. Zhou, Zhong-shan Wu, W. Yi, Yong Xu, Suling Li, Ting-Hai Xu, Yue Liu, Run-Ze Chen, A. Kovach, Yangyong Kang, L. Hou, Yuanzheng He, Cen Xie, Wanling Song, D. Zhong, Yechun Xu, Yonghong Wang, Jiayang Li, Chenghai Zhang, K. Melcher, H. E. Xu   +21 more
semanticscholar   +1 more source

Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults

Annals of Neurology, EarlyView.
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard, Ahmed Abdelhak, Rowan Saloner, Simone Sacco, Shivany C. Montes, Frederike C. Oertel, Christian Cordano, Nour Jabassini, Kirtana Ananth, Apraham Gomez, Azeen Keihani, Makenna Chapman, Sree Javvadi, Shikha Saha, Adam Staffaroni, Christopher Songster, Martin Warren, John W. Boscardin, Joel Kramer, Bruce Miller, Joshua W. Miller, Ralph Green, Ari J. Green   +22 more
wiley   +1 more source

Acid hydrolases of the rat uterus in relation to pregnancy, post-partum involution and collagen breakdown [PDF]

, 1965
JF WOESSNER
openalex   +1 more source

Konvergenter Aufbau Homo‐ und Heterotypischer Ubiquitinketten aus funktionaliserten, exprimierten Monomeren mittels Thiol‐En‐Chemie

Angewandte Chemie, EarlyView.
Die Erzeugung funktionalisierter Ubiquitinbausteine mittels Expression in E. coli bietet Zugang zu verschiedenen Di‐, Tri‐ und Tetra‐Ubiquitinketten. Photoinitiierte Thiol‐En‐Klickreaktionen werden dabei in Kombination mit einer Maskierungs‐ und Schutzgruppenstrategie zum kontrollierten Aufbau von Ubiquitinketten sowie zur Semisynthese von ...
Moritz Urschbach, Susanne Huhmann, Dominik Appel, Luca Ferrari, Dominik Vogl, Sascha Martens, Christian F. W. Becker   +6 more
wiley   +1 more source