Results 11 to 20 of about 21,144 (230)

Cinnamic-Hydroxamic-Acid Derivatives Exhibit Antibiotic, Anti-Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid-Associated Protein HU. [PDF]

Adv Sci (Weinh)
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Chen H, Xu Y, Xiong Z, Wang H, Wang X, Kang Y, Wang Z, Zeng X, Liu Y, Zheng Y, Chen W, Li M, Hu Z, Xu C, Wu Y, Wang Y, Yuan Z, Yuan S, Liu H, Matthews S, Qiao N, Li Y, Liu B.   +22 more
europepmc   +2 more sources

Preparation of cinnamic hydroxamic acid collector and study on flotation characteristics and mechanism of scheelite

International Journal of Mining Science and Technology, 2023
In this paper, using methyl cinnamate as raw material, the new cinnamic hydroxamic acid collector (CIHA) was synthesized by the hydroxylamine method. The collector performance of hydroxamic acid was investigated for scheelite and gangue calcite, and the ...
Xiang Yao, Xinyang Yu, Liping Wang, Yuhui Zeng, Linghan Mao, Shanming Liu, Honghui Xie, Guichun He, Zhiqiang Huang, Zhilin Liu   +9 more
doaj   +1 more source

Synthesis of poly (hydroxamic acid) ligand for removal of Cu (II) and Fe (II) ions in a single component aqueous solution

South African Journal of Chemical Engineering, 2021
Biosorbents are the alternatives for the removal of heavy metals because they are cheaper and more effective. This is attributed to the metallic elements interactions with the functional groups on the surface of the adsorbent.
Nozipho Nompumelelo Mzinyane, Augustine Enakpodia Ofomaja, Eliazer Bobby Naidoo   +2 more
doaj   +1 more source

SYNTHESIS AND IDENTIFICATION OF SOME HYDROXAMIC DERIVATIVES AND STUDYING THEIR THERMO AND PHOTO DEGRADATION [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2014
The aim of this research is to prepare and study the kinetics effect of temperature and photochemical reactions of the hydroxamic acid derivatives of diethyl succinate through the interaction of alkyl halides and diethyl succinate in the presence of ...
ISMAIL AL-KHATEEB, SADDA ABEDULLAH, SLMAN AHMED   +2 more
doaj   +1 more source

Phosphorus containing analogues of SAHA as inhibitors of HDACs

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Histone deacetylases (HDACs) are a family of enzymes responsible for regulating DNA transcription by modulating its binding to histone proteins. HDACs are overexpressed in several types of cancers and are recognised as drug targets.
Michael D. Pun, Hsin-Hua Wu, Feyisola P. Olatunji, Britany N. Kesic, John W. Peters, Clifford E. Berkman   +5 more
doaj   +1 more source

Adsorption of heavy metals from acid mine drainage using poly (hydroxamic acid) ligand

South African Journal of Chemical Engineering, 2022
Acid mine drainage (AMD) causes severe environmental concerns worldwide due to its high acidity, toxic metals and sulphate contents. Conventional treatment methods may not be effective for AMD.
Nozipho Nompumelelo Mzinyane
doaj   +1 more source

Hydroxamic acid surface active agents

Grasas y Aceites, 2001
p-Hydroxy phenyloctadecanol and p-hydroxy phenyloctadecanoic acid were used as new precursors for the preparation of surface active hydroxamic acid including different moles of propylene oxide.
M. H.M. Ahmed, A. A. Mahmoud, A. A. El-Sawy   +2 more
doaj   +1 more source

Preparation of hydroxoxime group-modified ultra-high molecular weight polyethylene fiber adsorbent by radiation-induced graft polymerization and its application to heavy metal ions removal

Fushe yanjiu yu fushe gongyi xuebao, 2023
The secondary grafting of acrylic acid and acrylamide onto ultra-high-molecular-weight polyethylene (UHMWPE) fibers was accomplished through 60Co gamma-ray pre-irradiation, and UHMWPE fiber adsorbents containing hydroxamic, amide, and carboxyl groups ...
HAO Xingfang, XIAN Chunying, WANG Hengdong, SHEN Li   +3 more
doaj   +1 more source

Green synthesized hydroxamic acid administered in high dose disrupts the antioxidant balance in the hepatic and splenic tissues of albino rats

Clinical Phytoscience, 2020
Background Hydroxamic acids are currently being used in diverse biological activities. We investigated the effect of hydroxamic acid, synthesized from Cyperus esculentus seeds, on the antioxidant status of the liver, spleen, and kidney of Wistar rats ...
Chiagoziem A. Otuechere, Adewale Adewuyi, Oluwabukola Bankole   +2 more
doaj   +1 more source

Methylation of 2-Aryl-2-(3-indolyl)acetohydroxamic Acids and Evaluation of Cytotoxic Activity of the Products

Molbank, 2021
2-Aryl-2-(3-indolyl)acetohydroxamic acids demonstrate promising antitumor activity, but quickly metabolize in vivo via glucuronidation of hydroxamic acid residue. In an attempt to improve their pharmacokinetics, methyl esters were synthesized via a newly
Dmitrii A. Aksenov, Alexander V. Aksenov, Lidiya A. Prityko, Nicolai A. Aksenov, Liliya V. Frolova, Michael Rubin   +5 more
doaj   +1 more source