Results 11 to 20 of about 30,744 (233)
Adsorption of heavy metals from acid mine drainage using poly (hydroxamic acid) ligand
Acid mine drainage (AMD) causes severe environmental concerns worldwide due to its high acidity, toxic metals and sulphate contents. Conventional treatment methods may not be effective for AMD.
Nozipho Nompumelelo Mzinyane
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Hydroxamic acid surface active agents
p-Hydroxy phenyloctadecanol and p-hydroxy phenyloctadecanoic acid were used as new precursors for the preparation of surface active hydroxamic acid including different moles of propylene oxide.
M. H.M. Ahmed +2 more
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The secondary grafting of acrylic acid and acrylamide onto ultra-high-molecular-weight polyethylene (UHMWPE) fibers was accomplished through 60Co gamma-ray pre-irradiation, and UHMWPE fiber adsorbents containing hydroxamic, amide, and carboxyl groups ...
HAO Xingfang +3 more
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Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer [PDF]
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, incurable cancer with a 20% 1 year survival rate. While standard-of-care therapy can prolong life in a small fraction of cases, PDAC is inherently resistant to current treatments, and novel ...
Adile, Ashley A. +19 more
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Background Hydroxamic acids are currently being used in diverse biological activities. We investigated the effect of hydroxamic acid, synthesized from Cyperus esculentus seeds, on the antioxidant status of the liver, spleen, and kidney of Wistar rats ...
Chiagoziem A. Otuechere +2 more
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2-Aryl-2-(3-indolyl)acetohydroxamic acids demonstrate promising antitumor activity, but quickly metabolize in vivo via glucuronidation of hydroxamic acid residue. In an attempt to improve their pharmacokinetics, methyl esters were synthesized via a newly
Dmitrii A. Aksenov +5 more
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Interactions of Bacillus Mojavensis and Fusarium Verticillioides With a Benzoxazolinone (Boa) and Its Transformation Product, Apo [PDF]
En:Journal of Chemical Ecology (2007, vol. 33, n. 10, p. 1885-1897)The benzoxazolinones, specifically benzoxazolin-2(3H)-one (BOA), are important transformation products of the benzoxazinones that can serve as allelochemicals providing resistance to ...
A. Baumeler +55 more
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Probing the Binding Requirements of Modified Nucleosides with the DNA Nuclease SNM1A
SNM1A is a nuclease that is implicated in DNA interstrand crosslink repair and, as such, its inhibition is of interest for overcoming resistance to chemotherapeutic crosslinking agents.
Eva-Maria Dürr, Joanna F. McGouran
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Hydroxamic acid - A novel molecule for anticancer therapy
Hydroxamic acid is a potent moiety not only in the field of cancer therapy but also as a mutagenic agent. Among the various derivatives of hydroxamic acid, SAHA (Suberoylanilide Hydroxamic Acid) is considered as a potent anticancer agent. Scientists from
Dilipkumar Pal, Supriyo Saha
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From Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis. [PDF]
In most eubacteria, apicomplexans, and most plants, including the causal agents for diseases such as malaria, leprosy, and tuberculosis, the methylerythritol phosphate pathway is the route for the biosynthesis of the C(5) precursors to the essential ...
de Oliveira, César Augusto F +3 more
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