Results 11 to 20 of about 7,346 (216)

Rapid Improvement of Hyperpigmentation, Growth, and Developmental Milestones With High‐Dose Hydroxocobalamin, Betaine, and Folinic Acid Treatment: The First Patient With Cobalamin G Deficiency in Taiwan [PDF]

JIMD Reports
In this report, we present the case of a 16‐month‐old patient who was diagnosed with cobalamin G deficiency at 4 months of age via whole exome sequencing by detecting compound heterozygous variants of uncertain significance (VUS) in the MTR gene: (1) c ...
Chi‐Tang Wu, Shih‐Ju Huang, Chu‐Chin Chen, Pao‐Chin Chiu   +3 more
doaj   +5 more sources

Evaluation of outcomes for patients with nitrous oxide-related myeloneuropathy treated with self-injection of hydroxocobalamin versus nurse-led injections on an ambulatory care pathway [PDF]

BMJ Neurology Open
Background Nitrous oxide (N₂O)-related neurotoxicity is a significant public health concern among young people in the UK. Recognition necessitates timely diagnosis, abstinence from N₂O consumption and replacement of vitamin B12, usually via intramuscular
Alastair J Noyce, Laura Smith, Marta Patyjewicz, Barbara Onen, Mohamoud Hashi, Katrina Mamigo, Eunice Adu-poku, Gillian Fox   +7 more
doaj   +4 more sources

A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias [PDF]

Journal of Pain Research, 2017
Henrique Goldberg,1 Marco Antonio Mibielli,2 Carlos Pereira Nunes,2 Stephanie Wrobel Goldberg,3 Luiz Buchman,4 Spyros GE Mezitis,5 Helio Rzetelna,6 Lisa Oliveira,2 Mauro Geller,2 Fernanda Wajnsztajn7 1UERJ Medical School, Rio de Janeiro, Brazil; 2UNIFESO
Goldberg H, Mibielli MA, Nunes CP, Goldberg SW, Buchman L, Mezitis SG, Rzetelna H, Oliveira L, Geller M, Wajnsztajn F   +9 more
doaj   +5 more sources

Hydroxocobalamin for the treatment of vasoplegia after lung transplantation: A case series [PDF]

JHLT Open
Background: The use of hydroxocobalamin following lung transplantation has not been previously reported. We present a series of 3 cases where hydroxocobalamin was used to treat postoperative vasoplegia.
Anh Nguyen, MD, PhD, Rima Bouajram, PharmD, Marek Brzezinski, MD, Sahand Hassanipour, David Gordon, Binh Trinh, MD, Tobias Deuse, MD, Aida Venado, MD, Steve Hays, MD, Jonathan Singer, MD, Jasleen Kukreja, MD, MPH   +10 more
doaj   +4 more sources

Analysis of hydroxocobalamin dosage in patients with CblC deficiency [PDF]

Orphanet Journal of Rare Diseases
Objective cblC deficiency is the most common organic acidemia in China. Hydroxocobalamin (OHCbl) is the main important therapeutic approach, while no approved protocols on its dosage during stable periods exist.
Si Ding, Yuxin Deng, Yi Ding, Lili Hao, Wenjuan Qiu, Huiwen Zhang, Lili Liang, Ting Chen, Xia Zhan, Peng Xu, Chiju Yang, Hui Zou, Yongxing Chen, Shengnan Wu, Yufeng Wang, Min Yang, Xuefan Gu, Xianting Jiao, Lianshu Han   +18 more
doaj   +4 more sources

Complete Immunophenotypic Reversal of Chronic Lymphocytic Leukaemia With High Dose Parenteral Methylcobalamin: A Case Report and Brief Review of Cobalamin in Cancer [PDF]

Cancer Reports
Background Supposed ‘spontaneous’ remissions in chronic lymphocytic leukaemia (CLL) are extremely rare. By the most stringent immunophenotypic criteria, there are only seven cases to date of unexplained, immune system effected cures. A historic review of
Carmen Wheatley
doaj   +3 more sources

Successful Renal Transplantation after Presumed Cyanide Toxicity Treated with Hydroxocobalamin and Review of the Literature [PDF]

Case Reports in Transplantation, 2018
We report two cases of successful renal transplantation with allografts from donors who suffered anoxic brain injury as the primary cause of death from house fires.
Ryan J. Hendrix, Paulo N. Martins, Jeffrey S. Stoff, Aaron Ahearn, Adel Bozorgzadeh, Babak Movahedi   +5 more
doaj   +2 more sources

A Case of Hydroxocobalamin-Induced False Blood Leak Alarm on Dialysis Machine [PDF]

Journal of Investigative Medicine High Impact Case Reports, 2019
Hemodialysis machines are equipped with a blood leak detector/alarm to prevent loss of blood following rupture of semipermeable membrane; the blood leak alarms could also be triggered by sensor malfunction or presence of air bubbles in the system ...
Praveen Datar MBBS, Jasdeep Singh Sidhu MBBS, Jeevanjot Virk MBBS, Osama Mukhtar MBBS, Frances Schmidt MD, Vijay Gayam MBBS   +5 more
doaj   +2 more sources

Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event [PDF]

Case Reports in Medicine, 2015
Cyanide is rapidly reacting and causes arrest of aerobic metabolism. The symptoms are diffuse and lethal and require high clinical suspicion. Remediation of symptoms and mortality is highly dependent on quick treatment with a cyanide antidote. Presently,
Andrew Meillier, Cara Heller
doaj   +2 more sources

Vitamin B12 (hydroxocobalamin) administration in the management of persistent vasoplegic shock [PDF]

Saudi Journal of Anaesthesia
Vasoplegia, characterized by low systemic vascular resistance despite normal to high cardiac output, can result from various conditions, including cardiac surgery, and progress to vasoplegic shock if untreated.
Jibran Ikram, Cassandra L. Williams, Aariya Srinivasan, Jose L. Diz Ferre, Sabry Ayad   +4 more
doaj   +2 more sources