Results 31 to 40 of about 7,137 (264)

Exploring the Accessibility by Using the Hydroxycobalamin Preparations of High Concentration in Treating Methylmalonic Acidemia

open access: yes罕见病研究, 2023
Methylmalonic acidemia(MMA) is one of the common diseases in hereditary organic acid metabolism disorder. The disorder is mainly treated by using vitamin B12 which comes in various forms.The use of the methylcobalamin and adenosylcobalamin in China ...
LI Ruohan   +3 more
doaj   +1 more source

Hydroxocobalamin for Vasodilatory Hypotension in Shock: A Systematic Review With Meta-Analysis for Comparison to Methylene Blue.

open access: yesJournal of Cardiothoracic and Vascular Anesthesia, 2023
Hydroxocobalamin inhibits nitric oxide-mediated vasodilation, and has been used in settings of refractory shock. However, its effectiveness and role in treating hypotension remain unclear.
Hannah M. Brokmeier   +6 more
semanticscholar   +1 more source

Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E

open access: yesMicroorganisms, 2023
Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence supporting the use of vitamin supplementation in viral infections, including severe acute ...
Yassmin Moatasim   +12 more
doaj   +1 more source

Homicide with intramuscular cyanide injection: a case report

open access: yesToxicology Communications, 2022
Cyanide poisoning most commonly occurs from smoke inhalation, less commonly by oral ingestion for suicide or homicide. There are rare cases of intravenous or subcutaneous parenteral cyanide.
Natasha Tobarran   +4 more
doaj   +1 more source

Watching Excited State Dynamics with Optical and X-ray Probes: The Excited State Dynamics of Aquocobalamin and Hydroxocobalamin.

open access: yesJournal of the American Chemical Society, 2023
Femtosecond time-resolved X-ray absorption (XANES) at the Co K-edge, X-ray emission (XES) in the Co Kβ and valence-to-core regions, and broadband UV-vis transient absorption are combined to probe the femtosecond to picosecond sequential atomic and ...
R. Sension   +21 more
semanticscholar   +1 more source

A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin

open access: yesEngineering Proceedings, 2023
The voltammetric behavior of hydroxocobalamin (OH-CBL) was firstly studied by employing a bare boron-doped diamond electrode as a working electrode. It was found that OH-CBL provided four anodic signals on BDDE in acidic supporting electrolytes and one ...
Lenka Janíková   +3 more
doaj   +1 more source

Spectrophotometric analysis of purple urine secondary to methylene blue and hydroxocobalamin co-administration

open access: yesJN. Journal of Nephrology (Milano. 1992), 2023
Background The development of purple urine after methylene blue (methylthioninium chloride) and hydroxocobalamin co-administration is a rare clinical entity that has not been fully elucidated. A 47-year-old male presented to the emergency department with
Jeremy Hardin   +4 more
semanticscholar   +1 more source

High‐dose hydroxocobalamin achieves biochemical correction and improvement of neuropsychiatric deficits in adults with late onset cobalamin C deficiency

open access: yesJIMD Reports, 2020
Cobalamin C (cblC) deficiency is the most common inborn error of intracellular cobalamin metabolism caused by pathogenic variant(s) in MMACHC and manifests with methylmalonic acidemia, hyperhomocysteinemia, and hypomethioninemia with a variable age of ...
Tomoyasu Higashimoto   +9 more
doaj   +1 more source

Comparison of hydroxocobalamin with other resuscitative fluids in volume-controlled and uncontrolled hemorrhage models in swine (Sus-scrofa)

open access: yesJournal of Trauma and Acute Care Surgery, 2023
Hydroxocobalamin was evaluated as possible resuscitation fluid, compared to clinically relevant resuscitation fluids, in pre-clinical models of controlled and uncontrolled hemorrhage.
PhD R. Madelaine Paredes   +6 more
semanticscholar   +1 more source

Pediatric Cyanide Poisoning After Ingestion of Apricot Seeds

open access: yesJournal of Pediatric Emergency and Intensive Care Medicine, 2020
Cyanide is one of the strongest and lethal poisons. Cyanide leads to tissue hypoxia and lactic acid accumulation. Hydroxocobalamin is a safe, fast and effective antidote that could be used, especially in children.
Yüksel Bıcılıoğlu   +3 more
doaj   +1 more source

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