Results 31 to 40 of about 7,346 (216)

Hydroxocobalamin [PDF]

open access: yesBlood, 1966
Abstract The mean hepatic biological half-life of Co57-hydroxocobalamin injected to 5 normal human subjects was similar to that of Co60-cyanocobalamin, as shown by double-label hepatic surface counting during the first 30 weeks after intramuscular or intravenous injection of cobalamins. In 2 cases in whom the counting was extended over a
GEORGE B. JERZY GLASS, DUK HO LEE
openaire   +3 more sources

A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin

open access: yesEngineering Proceedings, 2023
The voltammetric behavior of hydroxocobalamin (OH-CBL) was firstly studied by employing a bare boron-doped diamond electrode as a working electrode. It was found that OH-CBL provided four anodic signals on BDDE in acidic supporting electrolytes and one ...
Lenka Janíková   +3 more
doaj   +1 more source

Vitamin B12 induced acneiform eruption

open access: yesHeliyon, 2023
A 47-year-old, north african, male patient, has recently been diagnosed with pernicious anemia, treated with weekly intramuscular hydroxocobalamin.
Imane Bahbouhi   +3 more
doaj   +1 more source

Cyanide Production by Chromobacterium piscinae Shields It from Bdellovibrio bacteriovorus HD100 Predation [PDF]

open access: yes, 2017
Predation of Chromobacterium piscinae by Bdellovibrio bacteriovorus HD100 was inhibited in dilute nutrient broth (DNB) but not in HEPES. Experiments showed that the effector responsible was present in the medium, as cell-free supernatants retained the ...
Aruldass   +57 more
core   +2 more sources

The use of intravenous hydroxocobalamin as a rescue in methylene blue-resistant vasoplegic syndrome in cardiac surgery

open access: yesAnnals of Cardiac Anaesthesia, 2017
Vasoplegic syndrome is a well-recognized complication during cardiopulmonary bypass (CPB) and is associated with increased morbidity and mortality, especially when refractory to conventional vasoconstrictor therapy.
Yi Cai   +3 more
doaj   +1 more source

The use of hydroxocobalamin for vasoplegic syndrome in left ventricular assist device patients

open access: yesClinical Case Reports, 2020
We demonstrate evidence supporting the efficacy of hydroxocobalamin in reducing vasopressor requirements for LVAD patients with refractory vasoplegia. Further study is needed to substantiate these findings and determine its optimal use in practice.
Brian Ayers   +4 more
doaj   +1 more source

Receiving a diagnosis of Pernicious Anaemia: exploring experiences of relationships with health professionals [PDF]

open access: yes, 2019
Objectives: Pernicious Anaemia (PA) is a chronic condition caused by vitamin B12 deficiency. This is a qualitative study using interpretative phenomenological analysis (IPA); which aimed to explore the patients lived experience of diagnosis and ...
Glover, E., Mercer, Jenny, Seage, Heidi
core   +1 more source

Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1 beta, TNF-alpha, IL-6, and HMGB1 Expression [PDF]

open access: yes, 2013
Background. NOS/•NO inhibitors are potential therapeutics for sepsis, yet they increase clinical mortality. However, there has been no in vivo investigation of the (in vitro) •NO scavenger, cobalamin’s (Cbl) endogenous effects on NOS/•NO/inflammatory ...
Brancaleone, V   +5 more
core   +3 more sources

Protein dynamics in the reductive activation of a B12-containing enzyme [PDF]

open access: yes, 2017
B12-dependent proteins are involved in methyl transfer reactions ranging from the biosynthesis of methionine in humans to the formation of acetyl-CoA in anaerobic bacteria.
Goetzl, Sebastian   +6 more
core   +1 more source

Long-term outcome of a patient with Transcobalamin deficiency caused by the homozygous c.1115_1116delCA mutation in TCN2 gene: a case report

open access: yesItalian Journal of Pediatrics, 2021
Background Transcobalamin deficiency is a rare autosomal recessive inborn error of cobalamin transport (prevalence:
Francesco Martino   +6 more
doaj   +1 more source

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