Past, present and future of cyanide antagonism research: From the early remedies to the current therapies. [PDF]
, 2015 This paper reviews milestones in antidotal therapies for cyanide (CN) spanning early remedies, current antidotal systems and research towards next generation therapies. CN has been a part of plant defense mechanisms for millions of years.
Budai, Marianna +3 more
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Protein dynamics in the reductive activation of a B12-containing enzyme [PDF]
, 2017 B12-dependent proteins are involved in methyl transfer reactions ranging from the biosynthesis of methionine in humans to the formation of acetyl-CoA in anaerobic bacteria.
Goetzl, Sebastian +6 more
core +1 more source
Effect of hydroxocobalamin on nimodipine-induced refractory vasoplegia in a patient with liver cirrhosis [PDF]
Journal of Neurocritical CareBackground We report a case of severe vasoplegia that was unresponsive to triple vasopressor therapy but showed marked hemodynamic improvement following intravenous hydroxocobalamin administration in a patient with underlying cirrhosis.
Sungyong You
openalex +2 more sources
The use of hydroxocobalamin for vasoplegic syndrome in left ventricular assist device patients
Clinical Case Reports, 2020 We demonstrate evidence supporting the efficacy of hydroxocobalamin in reducing vasopressor requirements for LVAD patients with refractory vasoplegia. Further study is needed to substantiate these findings and determine its optimal use in practice.
Brian Ayers +4 more
doaj +1 more source
Early biomarker response and patient preferences to oral and intramuscular vitamin B12 substitution in primary care: a randomised parallel-group trial [PDF]
, 2017 Vitamin B12 (VB12) deficiency can be treated with oral high-dose substitution or intramuscular (i.m.) injection of VB12. Whenever alternative routes of administration exist, patient preferences should be considered when choosing the treatment.
Arnet, Isabelle +5 more
core +2 more sources
Annals of Cardiac Anaesthesia, 2017 Vasoplegic syndrome is a well-recognized complication during cardiopulmonary bypass (CPB) and is associated with increased morbidity and mortality, especially when refractory to conventional vasoconstrictor therapy.
Yi Cai +3 more
doaj +1 more source
A New, Atypical Case of Cobalamin F Disorder Diagnosed by Whole Exome Sequencing [PDF]
, 2015 The Deciphering Developmental Disorders Study presents independent research commissioned by the Health Innovation Challenge Fund (HICF-1009-003), a parallel funding partnership between the Wellcome Trust and the Department of Health, and the Wellcome ...
Constantinou, Panayiotis +6 more
core +1 more source
Case Reports in Transplantation, 2018 We report two cases of successful renal transplantation with allografts from donors who suffered anoxic brain injury as the primary cause of death from house fires.
Ryan J. Hendrix +5 more
doaj +1 more source
Italian Journal of Pediatrics, 2021 Background Transcobalamin deficiency is a rare autosomal recessive inborn error of cobalamin transport (prevalence:
Francesco Martino +6 more
doaj +1 more source
Cyanide Production by Chromobacterium piscinae Shields It from Bdellovibrio bacteriovorus HD100 Predation [PDF]
, 2017 Predation of Chromobacterium piscinae by Bdellovibrio bacteriovorus HD100 was inhibited in dilute nutrient broth (DNB) but not in HEPES. Experiments showed that the effector responsible was present in the medium, as cell-free supernatants retained the ...
Aruldass +57 more
core +2 more sources