Results 121 to 130 of about 6,850 (177)

Unraveling enantioselective metabolism: Human cytochrome P450s in arachidonic acid biotransformation. [PDF]

Drug Metab Dispos
Isse FA, El-Sherbeni AA, El-Kadi AOS.
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Plasma Biomarker Profiling of 2-Hydroxypropyl-β-Cyclodextrin (HPβCD) Treatment in an Aged Mouse Model of Ischemic Stroke. [PDF]

Int J Mol Sci
Becktel DA, Frye JB, Le EH, Schnellmann RG, Doyle KP.   +4 more
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Pro-Coagulant Lipids in Physiological Ratios Found in the Activated Platelet Membrane Do Not Impact Clot Structure or Fibrinolysis in Purified Assays. [PDF]

J Blood Med
Morgan BH, Farleigh Smith LE, Costa DO, Tyrrell VJ, Ahnström J, Jenkins PV, Collins PW, Mutch NJ, O'Donnell VB.   +8 more
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Oxylipin serum profile changes in response to an open-label anti-inflammatory dietary intervention. [PDF]

Clin Nutr ESPEN
Sala-Climent M, Lal E, Cedola F, Alharthi M, Fernandez-Bustamante M, Agustin-Perez M, Singh A, Choi SI, Rivera T, Nguyen K, Lee S, Golshan S, Holt T, Quehenberger O, Coras R, Guma M.   +15 more
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Brain Microvessels Produce 12‐Hydroxyeicosatetraenoic Acid

Journal of Neurochemistry, 1989
Abstract: Cerebral microvessels isolated from perfused, adult murine brain produce a compound with the chromatographic properties of a monohydroxyeicosatetraenoic acid when incubated with arachidonic acid or stimulated with calcium ionophore A23187. The formation of this arachidonic acid metabolite is not reduced in the presence of the cyclooxy‐genase ...
S A, Moore, P H, Figard, A A, Spector, M N, Hart   +3 more
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5-Hydroxyeicosatetraenoic acid and human parturition

Prostaglandins, 1996
5-Hydroxyeicosatetraenoic acid (5-HETE) is an arachidonic acid (AA) metabolite derived from the lipoxygenase pathway which is capable of inducing uterine contractions. The purpose of this study was to determine a). whether 5-HETE concentrations in amniotic fluid increase before or after the onset of labor and b).
Edwin, S. S., Romero, R. J., Munoz, H., Branch, D. W., Mitchell, M. D.   +4 more
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Augmentation of IgE-mediated release of histamine by 5-hydroxyeicosatetraenoic acid and 12-hydroxyeicosatetraenoic acid

Biochemical and Biophysical Research Communications, 1980
Abstract Highly purified rat mast cells converted 1.12% and 1.64% of exogenously added [1- 14 C]arachidonic acid to 5-OH-6,8,11,14 eicosatetraenoic acid (5-HETE) and 12-OH-5,8,10,14 eicosatetraenoic acid (12-HETE) respectively during a three minute incubation at 37°.
W F, Stenson, C W, Parker, T J, Sullivan
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Characterization of hydroxyeicosatetraenoic acids and hydroxyeicosatetraenoic acid phosphatidylcholines by liquid secondary ion tandem mass spectrometry

Biological Mass Spectrometry, 1994
Arachidonic acid is oxidized to regioisomeric 5(S)-, 12(S)- and 15(S)-hydroxyeicosatetraenoic acids by the corresponding 5-, 12- and 15-lipoxygenases. These hydroxylated fatty acids can then be incorporated into cellular phospholipids. Negative liquid secondary ion tandem mass spectrometry using a high-energy collision regime in a tandem four-sector ...
J Y, Zhang, B J, Nobes, J, Wang, I A, Blair   +3 more
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20-Hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure

Current Opinion in Nephrology and Hypertension, 2001
The properties of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids, vasoactivity and modulation of ion transport and mediation/modulation of the effects of vasoactive hormones, such as angiotensin II and endothelin, underscore their importance to renal vascular mechanisms and electrolyte excretion.
J C, McGiff, J, Quilley
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