Results 51 to 60 of about 5,905,176 (286)
Journal of Lipid Research, 2018 Lipoxygenases (LOXs) catalyze the dioxygenation of PUFAs to produce regio- and stereospecific oxygenated fatty acids. The identification of regio- and stereospecific LOXs is important because their specific products are involved in different ...
Jung-Ung An, Deok-Kun Oh
doaj +1 more source
Efficacy of ω-3 supplementation in patients with psoriasis:a meta-analysis of randomized controlled trials [PDF]
, 2019 Several studies have been conducted with the aim of investigating the effect of Omega(Ï )-3 on different psoriasis indices including Psoriasis Area and Severity Index (PASI) score, erythema, scaling, itching, area involved, and infiltration. Nevertheless,
Clark, Cain +3 more
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Bone-Targeted Delivery of Novokinin as an Alternative Treatment Option for Rheumatoid Arthritis
Pharmaceutics, 2022 Rheumatoid arthritis (RA) is an autoimmune inflammatory bone destructive disorder that is orchestrated by multiple systems in the body, including Renin-Angiotensin System (RAS) and arachidonic acid (ArA) pathway.
Arina Ranjit +2 more
doaj +1 more source
The emerging role of oxylipins in thrombosis and diabetes. [PDF]
, 2014 The prevalence of cardiovascular disease (CVD), the leading cause of death in the US, is predicted to increase due to the shift in age of the general population and increase in CVD risk factors such as obesity and diabetes.
Ahmed, Intekhab +2 more
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Journal of Biological Chemistry, 1990 Incubation of rat liver microsomal fractions with arachidonic acid in the presence of NADPH results in the formation of three novel monohydroxylated fatty acid metabolites.
J. Falck +7 more
semanticscholar +1 more source
Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. [PDF]
PLoS ONE, 2013 INTRODUCTION:Conflicting findings in both interventional and observational studies have resulted in a lack of consensus on the benefits of ω3 fatty acids in reducing disease risk. This may be due to individual variability in response.
Malin L Nording +9 more
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Outlining eicosanoid biosynthesis in the crustacean [PDF]
, 2008 Background Eicosanoids are biologically active, oxygenated metabolites of three C20 polyunsaturated fatty acids. They act as signalling molecules within the autocrine or paracrine system in both vertebrates and invertebrates mainly functioning as ...
Callaghan Amanda +3 more
core +3 more sources
Journal of Biological Chemistry, 2001 Norepinephrine (NE) stimulates phospholipase D (PLD) through a Ras/MAPK pathway in rabbit vascular smooth muscle cells (VSMC). NE also activates calcium influx and calmodulin (CaM)-dependent protein kinase II-dependent cytosolic phospholipase A2(cPLA2 ...
J. Parmentier +3 more
semanticscholar +1 more source
Temperature and time-dependent effects of delayed blood processing on oxylipin concentrations in human plasma. [PDF]
, 2019 BACKGROUND:Oxidized derivatives of polyunsaturated fatty acids, collectively known as oxylipins, are labile bioactive mediators with diverse roles in human physiology and pathology.
Gibson, Robert A +8 more
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Renal And Cardiovascular Actions Of 20‐Hydroxyeicosatetraenoic Acid And Epoxyeicosatrienoic Acids [PDF]
Clinical and Experimental Pharmacology and Physiology, 2000 SUMMARY1. Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP)‐dependent pathways to epoxyeicosatrienoic acids (EET) and 20‐hydroxyeicosatetraenoic acid (20‐HETE) in the kidney and the peripheral vasculature.2. The present short review summarizes the renal and cardiovascular actions of these important mediators.3. Epoxyeicosatrienoic acids are
R J, Roman +4 more
openaire +2 more sources