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Probing the dynamics and bottleneck of the key atmospheric SO2 oxidation reaction by the hydroxyl radical. [PDF]
Yuan DF +7 more
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Dark formation of hydroxyl radicals (°OH) upon aeration of anoxic lake water
Marco Minella +4 more
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Cold Spring Harbor Protocols, 2007
INTRODUCTIONThe hydroxyl-radical footprinting methodology has wide applications to studying protein-DNA interactions, as well as structural perturbations (e.g., bending) that occur in DNA during protein binding. Hydroxyl radicals cleave DNA by abstracting a hydrogen atom from C4 of the sugar in the minor groove.
Michael, Carey, Stephen T, Smale
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INTRODUCTIONThe hydroxyl-radical footprinting methodology has wide applications to studying protein-DNA interactions, as well as structural perturbations (e.g., bending) that occur in DNA during protein binding. Hydroxyl radicals cleave DNA by abstracting a hydrogen atom from C4 of the sugar in the minor groove.
Michael, Carey, Stephen T, Smale
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An optical hydroxyl radical sensor
Biosensors and Bioelectronics, 1993A hydroxyl radical (.OH) fibre-optic sensor has been developed. An .OH radical-sensitive reagent phase (nitrophenol) was immobilized onto XAD-7 methacrylate beads. Subsequently the beads were attached to the distal end of a polymethylmethacrylate fibre optic.
D P, Naughton +4 more
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Hydroxyl radical formation by dithranol
Biochemical Pharmacology, 1988Ethene formation from 2-keto-thiomethyl-butyric acid (KMBA) was used to measure hydroxyl radical generation from the antipsoriatic drug dithranol in phosphate buffer pH 7.8. Because the singlet oxygen (1O2) sensitizer, rose bengale, showed enlarged production of ethene when irradiated in the presence of KMBA, experiments were performed in the dark in ...
K, Müller, H, Kappus
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Hydroxyl Radical Reactivity with Diethylhydroxylamine
Science, 1977Diethylhydroxylamine (DEHA) reacts with gas-phase hydroxyl radicals on every third collision, whereas the corresponding reaction in aqueous solution is considerably slower. The high gas-phase reactivity explains the predicted inhibitory effect of DEHA in atmospheric smog processes. Results from the studies in the aqueous phase are helpful in predicting
R A, Gorse, R R, Lii, B B, Saunders
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Clindamycin phosphate scavenges hydroxyl radical
International Journal of Dermatology, 2007AbstractBackground Clindamycin phosphate (CLDMP) is effective against Gram‐positive and anaerobic bacteria, and is known to have anti‐inflammatory properties.Methods To further study the anti‐inflammatory properties of CLDMP, we examined the scavenging effects on superoxide anion and hydroxyl radical using an electron spin resonance (ESR) spin ...
Sato E, Kato M, Kohno M, Niwano Y
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Analytical Biochemistry, 1981
Abstract A mixture of xanthine or hypoxanthine and xanthine oxidase generates the superoxide radical, O2 • , and H2O2. In the presence of iron salts, O2 • and H2O2 can interact to produce the hydroxyl radical, OH·. Superoxide-dependent formation of OH· can be measured by its ability to hydroxylate salicylate as followed by an improved ...
R, Richmond +3 more
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Abstract A mixture of xanthine or hypoxanthine and xanthine oxidase generates the superoxide radical, O2 • , and H2O2. In the presence of iron salts, O2 • and H2O2 can interact to produce the hydroxyl radical, OH·. Superoxide-dependent formation of OH· can be measured by its ability to hydroxylate salicylate as followed by an improved ...
R, Richmond +3 more
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Hydroxylation of 3-nitrotyrosine by hydroxyl radical
Chinese Chemical Letters, 2007Abstract Hydroxylation of 3-nitrotyrosine (3-NT) and 3-NT containing peptide Gly-nitroTyr-Gly in aqueous solution by hydroxyl radical were investigated with gamma irradiation. The structures of the hydroxylated products were confirmed by electrospray ionization mass spectrometry and 1 H NMR spectrometry.
Jun Chen Dong +3 more
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