Results 61 to 70 of about 268,094 (306)

Probing the mechanism of electron capture and electron transfer dissociation using tags with variable electron affinity [PDF]

open access: yes, 2009
Electron capture dissociation (ECD) and electron transfer dissociation (ETD) of doubly protonated electron affinity (EA)-tuned peptides were studied to further illuminate the mechanism of these processes. The model peptide FQpSEEQQQTEDELQDK, containing a
Beauchamp, J. L.   +5 more
core   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Re-assessing hydroxyl radical chemistry in the atmosphere: Instrument interferences may explain previous measurement discrepancies

open access: yesCommunications Earth & Environment
The hydroxyl radical controls the removal of many trace gases in the atmosphere and initiates the production of secondary pollutants such as ground-level ozone and secondary organic aerosols.
Paige Price   +4 more
doaj   +1 more source

Antioxidant Activity In Vitro Guided Screening and Identification of Flavonoids Antioxidants in the Extract from Tetrastigma hemsleyanum Diels et Gilg

open access: yesInternational Journal of Analytical Chemistry, 2021
This study aimed to investigate the extract with high antioxidant activity of Tetrastigma hemsleyanum Diels et Gilg and identify the antioxidant components in vitro.
Li Ding, Xiaomin Zhang, Jiajia Zhang
doaj   +1 more source

One-electron oxidation and reduction of glycosaminoglycan chloramides: a kinetic study. [PDF]

open access: yes, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, these being significant components of the extracellular matrix (ECM).
A.W.J. Paterson   +67 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Finding and characterizing the complexes of drug like molecules with quadruplex DNA: combined use of an enhanced hydroxyl radical cleavage protocol and NMR.

open access: yesPLoS ONE, 2014
Structural information on the complexes of drug like molecules with quadruplex DNAs can aid the development of therapeutics and research tools that selectively target specific quadruplex DNAs.
Harikrushan Ranpura   +2 more
doaj   +1 more source

Representing Organic Compound Oxidation in Chemical Mechanisms for Policy-Relevant Air Quality Models under Background Troposphere Conditions

open access: yesAtmosphere, 2020
This intercomparison has taken thirteen chemical mechanisms and compared how they treat VOC oxidation and degradation and its relationship to the photochemical formation of ozone and hydroxyl radicals.
Richard G. Derwent
doaj   +1 more source

Saturated laser fluorescence in turbulent sooting flames at high pressure [PDF]

open access: yes, 1984
The primary objective was to develop a quantitative, single pulse, laser-saturated fluorescence (LSF) technique for measurement of radical species concentrations in practical flames.
Carter, C. D.   +2 more
core   +1 more source

Surface reactivity of amphibole asbestos. A comparison between crocidolite and tremolite [PDF]

open access: yes, 2017
Among asbestos minerals, fibrous riebeckite (crocidolite) and tremolite share the amphibole structure but largely differ in terms of their iron content and oxidation state. In asbestos toxicology, iron-generated free radicals are largely held as one of
Andreozzi, Giovanni B.   +4 more
core   +3 more sources

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