Results 131 to 140 of about 10,848 (250)

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Light‐Induced Reactions of Small‐Membered Cyclic Carbonyl Compounds

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
This review highlights recent advances in the synthesis and photochemical reactivity of cyclopropenone and cyclobutenedione. These compounds undergo photolysis upon direct excitation, and in some cases, through indirect excitation by photocatalysts. The resulting photogenerated species exhibit unique reactivity profiles that are strongly influenced by ...
Kenji Mishiro
wiley   +1 more source

Electrochemical Dehydration of Carboxamides to Their Nitriles

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
Electrochemical dehydration of carboxamides to nitriles is achieved using thiocyanate‐mediated activation, avoiding stoichiometric reagents. In an undivided cell at ambient conditions, 18 aromatic and aliphatic substrates give good‐to‐excellent yields (up to 84%) with functional‐group tolerance. Cyclic voltammetry supports an EC‐type‐mediated oxidation.
Enrico Lunghi, Annemijn M. van Koten, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

Alpha‐Ester Aryl Diazirines: Low‐Temperature Carbene Progenitors for Materials Applications

Advanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.
A synthetic route to α‐ester aryl diazirines is established. The products are shown to have low activation temperatures, and to form stabilized singlet carbenes, resulting in high‐yielding C–H insertion to unactivated aliphatic bonds. Applications in materials science and tissue adhesion are proposed.
Kate Andersen, Nora Struchtrup, Adam Sylvain‐Stewart, Liliia Pestereva, Benjamin Godwin, Gino A. DiLabio, Jeremy E. Wulff   +6 more
wiley   +1 more source

The contribution of drugs and toxins to understanding of cholinergic function. [PDF]

, 1990
Whittaker, V.
core   +1 more source

Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis

Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger, Nika Podlesnik, Francesco Mele, Michael Schnürch   +3 more
wiley   +1 more source

O-Benzyl-N-(9-acridinyl)hydroxylamines

ARKIVOC, 2018
Alyssa L. Johnson, Nathan Duncan, Michael D. Mosher   +2 more
doaj   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, Mariia Moshkova, Iuliia Pilipenko, David W. Cescon, Eugenia Kumacheva   +7 more
wiley   +1 more source

Nitrones: Comprehensive Review on Synthesis and Applications. [PDF]

Molecules
Santos RALS, Silva AMS, Pinto DCGA.
europepmc   +1 more source

Nicotinamide phosphoribosyltransferase inhibitors, design, preparation and SAR. [PDF]

, 2013
Annemette Thougaard, Antje Garten, Beauparlant P., Becke A. D., Becke A. D., Binderup E., Butera J. A., Cea M., Colombano G., Deraeve C., Diefenbach J., Ditchfield R., Einars Loza, Elliott G. C., Elstner M., Fleischer T. C., Foster J. W., Fredrik Björkling, Galli U., Garten A., Genazzani A. A., Grimme S., Gross J. W., Hageman G. J., Hasmann M., Holen K., Hovstadius P., Hufton S. E., Humljan J., Ivars Kalvinsh, Jette Tjørnelund, Kamille D. Erichsen, Khan J. A., Khan J. A., Kim M. K., Kornet M. J., Lee C., Lengauer C., Linderoth L., Magni G., Malavasi F., Maxwell Sehested, Mette K. Christensen, Nahimana A., Natarajan A., Nomura F., Olesen U. H., Olesen U. H., Olesen U. H., Orwig K. S., Peter B. Jensen, Peter Fristrup, Preiss J., Preiss J., Rongvaux A., Saunders L. R., Schou C., Shackelford R. E., Skelton L. A., Søren Jensby Nielsen, Uffe H. Olesen, van Beijnum J. R., Wang B., Watson M., Wieland Kiess, Zhao X., Ziegler M.   +66 more
core   +1 more source