Results 1 to 10 of about 97,747 (236)
Horticulture Research, 2022 Flavonoids are the most widespread polyphenolic compounds and are important dietary constituents present in horticultural crops such as fruits, vegetables, and tea.
Yilong Liu +8 more
semanticscholar +1 more source
A tautomeric ligand enables directed C‒H hydroxylation with molecular oxygen
Science, 2021 Easing oxygen into arenes Although oxygen is all around us, it is often surprisingly difficult to use it for selective chemical oxidations, necessitating more expensive, wasteful alternatives. Li et al.
Zhen Li +8 more
semanticscholar +1 more source
Decarboxylative Hydroxylation of Benzoic Acids
Angewandte Chemie, 2021 Herein, we report the first decarboxylative hydroxylation to synthesize phenols from benzoic acids at 35 °C via photoinduced ligand‐to‐metal charge transfer (LMCT)‐enabled radical decarboxylative carbometalation.
Wanqi Su, P. Xu, T. Ritter
semanticscholar +1 more source
Frontiers in Catalysis, 2022 The use of water-miscible organic co-solvents in biocatalysis is a simple procedure for obtaining higher enzymatic activities toward hydrophobic substrates.
Thomas Hilberath +3 more
doaj +1 more source
Nature Communications, 2020 mTORC1 is an important regulator of muscle mass but how it is modulated by oxygen and nutrients is not completely understood. We show that loss of the prolyl hydroxylase domain isoform 1 oxygen sensor in mice (PHD1KO) reduces muscle mass.
G. D’Hulst +13 more
semanticscholar +1 more source
Frontiers in Chemistry, 2022 Dihydroartemisinin (DHA) is a sesquiterpene endoperoxide with prominent antimalarial efficacy, which was discovered by Professor Youyou Tu through the reduction of artemisinin in the 1970s.
Yue Bai +6 more
doaj +1 more source
Peroxide-Mediated Oxygenation of Organic Compounds by Fungal Peroxygenases
Antioxidants, 2022 Unspecific peroxygenases (UPOs), whose sequences can be found in the genomes of thousands of filamentous fungi, many yeasts and certain fungus-like protists, are fascinating biocatalysts that transfer peroxide-borne oxygen (from H2O2 or R-OOH) with high ...
Martin Hofrichter +6 more
doaj +1 more source
A New Stilbene Glucoside from Biotransformation-Guided Purification of Chinese Herb Ha-Soo-Oh
Plants, 2022 Ha-Soo-Oh is a traditional Chinese medicine prepared from the roots of Polygonum multiflorum Thunb. The herb extract has been widely used in Asian countries as a tonic agent and nutritional supplement for centuries. To identify new bioactive compounds in
Jiumn-Yih Wu +4 more
doaj +1 more source
Conversion of Unsaturated Short- to Medium-Chain Fatty Acids by Unspecific Peroxygenases (UPOs)
Applied Microbiology, 2023 Eighteen short- to medium-chain monounsaturated fatty acids were screened for hydroxylation and epoxidation using eleven different peroxygenase preparations.
Alexander Karich +5 more
doaj +1 more source
Designed whole-cell-catalysis-assisted synthesis of 9,11-secosterols
Beilstein Journal of Organic Chemistry, 2021 A method for the synthesis of 9,11-secosteroids starting from the natural corticosteroid cortisol is described. There are two key steps in this approach, combining chemistry and synthetic biology.
Marek Kõllo +7 more
doaj +1 more source