Results 11 to 20 of about 66,196 (244)
Frontiers in Catalysis, 2022 The use of water-miscible organic co-solvents in biocatalysis is a simple procedure for obtaining higher enzymatic activities toward hydrophobic substrates.
Thomas Hilberath +3 more
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A New Stilbene Glucoside from Biotransformation-Guided Purification of Chinese Herb Ha-Soo-Oh
Plants, 2022 Ha-Soo-Oh is a traditional Chinese medicine prepared from the roots of Polygonum multiflorum Thunb. The herb extract has been widely used in Asian countries as a tonic agent and nutritional supplement for centuries. To identify new bioactive compounds in
Jiumn-Yih Wu +4 more
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Peroxide-Mediated Oxygenation of Organic Compounds by Fungal Peroxygenases
Antioxidants, 2022 Unspecific peroxygenases (UPOs), whose sequences can be found in the genomes of thousands of filamentous fungi, many yeasts and certain fungus-like protists, are fascinating biocatalysts that transfer peroxide-borne oxygen (from H2O2 or R-OOH) with high ...
Martin Hofrichter +6 more
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Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates
Beilstein Journal of Organic Chemistry, 2013 A regio- and stereoselective method has been developed for the synthesis of novel fluorinated 2-aminocyclohexanecarboxylic acid derivatives with the fluorine attached to position 4 of the ring.
Loránd Kiss +4 more
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Molecules, 2019 The inhibition of recombinant CpLIP2 lipase/acyltransferase from Candida parapsiolosis was considered a key model for novel antifungal drug discovery and a potential therapeutic target for candidiasis. Lipases have identified recently as potent virulence
Ruba Nasri +6 more
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Conversion of Unsaturated Short- to Medium-Chain Fatty Acids by Unspecific Peroxygenases (UPOs)
Applied Microbiology, 2023 Eighteen short- to medium-chain monounsaturated fatty acids were screened for hydroxylation and epoxidation using eleven different peroxygenase preparations.
Alexander Karich +5 more
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Biotransformation of Isoflavone Using Enzymatic Reactions
Molecules, 2013 The roles of cytochrome P450 monooxygenases (CYPs) from Streptomyces spp. which are called the “treasure islands” for natural products for medicine and antibiotics are not well understood.
Changhyun Roh
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Efficient hydroxylation of flavonoids by using whole-cell P450 sca-2 biocatalyst in Escherichia coli
Frontiers in Bioengineering and Biotechnology, 2023 The hydroxylation is an important way to generate the functionalized derivatives of flavonoids. However, the efficient hydroxylation of flavonoids by bacterial P450 enzymes is rarely reported.
Baodong Hu +24 more
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Designed whole-cell-catalysis-assisted synthesis of 9,11-secosterols
Beilstein Journal of Organic Chemistry, 2021 A method for the synthesis of 9,11-secosteroids starting from the natural corticosteroid cortisol is described. There are two key steps in this approach, combining chemistry and synthetic biology.
Marek Kõllo +7 more
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Frontiers in Chemistry, 2022 Dihydroartemisinin (DHA) is a sesquiterpene endoperoxide with prominent antimalarial efficacy, which was discovered by Professor Youyou Tu through the reduction of artemisinin in the 1970s.
Yue Bai +6 more
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