Journal of Cancer Research and Clinical Oncology, 1995 Competitive inhibitors of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase are currently used to treat patients with hypercholesterolaemia. These inhibitors affect not only cholesterol biosynthesis, but also the production of non-steroidal mevalonate derivatives, that are involved in a number of growth-regulatory processes.
Angelika Gebhardt, Axel Niendorf
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Prevention of medication-related osteonecrosis of the jaw by local application of atelocollagen containing a hydroxymethylglutaryl-CoA reductase inhibitor to the MRONJ model rat tooth extraction socket2023 application ...
Yosuke Kikuchi +3 more
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Hydroxymethylglutaryl-CoA reductase inhibitors (statins) for the treatment of sepsis in adults—Authors’ reply [PDF]
Clinical Microbiology and Infection, 2019 Barak Pertzov +5 more
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Lijecnicki vjesnik, 2011 Hydroxymethylglutaryl-CoA reductase inhibitors (statins) are drugs used in the treatment of chronic diseases and frequently in concomitant therapy with many other drugs. Therefore, the risk of adverse drug reactions (ADRs), especially those caused by interactions is high.
Nikica Mirošević Skvrce +3 more
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Re: ‘Hydroxymethylglutaryl-CoA reductase inhibitors (statins) for the treatment of sepsis in adults’ by Pertzov et al. [PDF]
Clinical Microbiology and Infection, 2019 Xianshi Zhou, Guanghua Tang
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Role of Blood Lipid Levels and Lipid-Lowering Therapy in Stroke Patients with Different Levels of Cerebral Artery Diseases: Reconsidering Recent Stroke Guidelines [PDF]
Journal of Stroke, 2021 Hyperlipidemia is an important risk factor for ischemic stroke; the Stroke Prevention by Aggressive Reduction in Cholesterol Level and Treat Stroke to Target studies have shown that statins are beneficial for patients with stroke and that a low target ...
Jong S. Kim
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Early efficacy and safety of statin therapy in Korean patients with hypercholesterolemia: Daegu and Gyeongbuk Statin Registry [PDF]
The Korean Journal of Internal Medicine, 2020 Background/Aims To date, prospective data are limited on efficacy and safety profiles of statin therapy in Korean hypercholesterolemic patients. Hence, the aim of this study was to evaluate the practice patterns of statin therapy and its efficacy and ...
Han Joon Bae +11 more
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Effect of atorvastatin on systolic and diastolic function in patients with heart failure with reduced ejection fraction (HFrEF) [PDF]
Medicinski Glasnik, 2021 Aim To investigate the benefit of high-dose lipophilic statin therapy on cardiac remodelling, function and progression of heart failure (HF) in patients with ischemic heart disease.
Faris Zvizdić +4 more
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Should all patients with psoriasis receive statins? Analysis according to different strategies, [PDF]
Anais Brasileiros de Dermatologia, 2020 Background: Different strategies have been proposed for the cardiovascular risk management of patients with psoriasis. Objective: To estimate the cardiovascular risk and evaluate two cardiovascular prevention strategies in patients with psoriasis ...
Walter Masson +3 more
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Beneficial Effects of Statins on Seizures Independent of Their Lipid-Lowering Effect: A Narrative Review [PDF]
Iranian Journal of Medical Sciences, 2023 Among the many types of central nervous system (CNS) disorders, seizures and epilepsy severely affect the quality of life and routine daily activity of the sufferers.
Arash Amanlou +4 more
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