Results 71 to 80 of about 21,088 (210)

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 12, Page 3679-3689, December 2025.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao   +11 more
wiley   +1 more source

The Carba Mix—In Vitro Investigations of Potential Cocktail Effects in Patch Tests With Rubber Allergens

open access: yesContact Dermatitis, Volume 93, Issue 4, Page 316-327, October 2025.
The carba mix was studied in a human cell model to better understand human patch reactions to the mix. Our results support that the carba mix can give rise to cocktail effect and that patch testing with separate carba mix sensitisers may thus be more appropriate.
Linda Ljungberg Silic   +5 more
wiley   +1 more source

Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies

open access: yesFundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT This review highlights the integration of drug repurposing and nanotechnology‐driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidiasis, providing a framework for future translational research and clinical application.
Dominique Mesquita e Silva   +8 more
wiley   +1 more source

Quorum sensing for improved production of industrially useful products from filamentous fungi [PDF]

open access: yes, 2014
Quorum sensing (QS) is a cell density dependant phenomena utilized as a communication process among microorganisms to regulate their physiological responses. QS depends on the production and release of low molecular weight, diffusible chemical signalling
Amache, R., Amache, R.
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Gut Microbiota‐Derived Metabolites Orchestrate Metabolic Reprogramming in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Frontiers

open access: yesThe FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Schematic representation of how gut microbiota‐derived metabolites—such as SCFAs, TMAO, and tryptophan derivatives—modulate cardiac energy metabolism, inflammation, and epigenetic regulation, contributing to the pathogenesis of diabetic cardiomyopathy. Therapeutic strategies targeting the gut–heart axis hold translational promise for metabolic cardiac ...
Jing‐yu Jin   +12 more
wiley   +1 more source

Characterization of labrenzin biosynthesis in marine alphaproteobacterium Labrenzia sp. PHM005 [PDF]

open access: yes, 2021
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología.
Kacar, Dina
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Pleurotus Mushrooms in Nutrition and Health: Clinical and Preclinical Insights for Nutraceutical Development

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 5, September 2025.
ABSTRACT Pleurotus mushrooms are fungi widely consumed due to their high nutritional value and potential applications as nutraceuticals. Their sustainable cultivation and rich composition of bioactive compounds provide significant health benefits. This review examines the scientific evidence regarding the safety, efficacy, and nutraceutical potential ...
Patrícia Lima Araújo   +7 more
wiley   +1 more source

Effect of Statins and PCSK9 Inhibition on Metabolic Dysfunction–Associated Steatotic Liver Disease

open access: yesJournal of Digestive Diseases, Volume 26, Issue 9-10, Page 392-397, September-October 2025.
Statins reduce low‐density lipoprotein‐cholesterol (LDL‐C) production and reduce cardiovascular risk and hepatic steatosis in metabolic dysfunction‐associated steatotic liver disease (MASLD), but they have no significant effect on steatohepatitis and/or fibrosis.
Eleni Theocharidou, Thomas Gossios
wiley   +1 more source

Структурно-функциональные изменения фотосинтетического аппарата как один из путей повышения неспецифической устойчивости растений : этап 3 [PDF]

open access: yes, 2011
В отчете представлены результаты исследований, выполненных по 3 этапу Государственного контракта № П2364 "Структурно-функциональные изменения фотосинтетического аппарата как один из путей повышения неспецифической устойчивости растений." (шифр "НК-421П")
Борисова, Г. Г.   +9 more
core  

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