Results 101 to 110 of about 100,236 (366)

Nanomaterial‐Integrated 3D Biofabricated Structures for Advanced Biomedical Applications

Macromolecular Materials and Engineering, EarlyView.
This review investigates the integration of nanomaterials into 3D biofabricated structures, highlighting the potential in tissue regeneration, wound healing, and cancer therapy. It discusses key techniques, including bioprinting and electrospinning, while addressing challenges such as biocompatibility, scalability, and regulatory barriers.
Mustafijur Rahman, Tanvir Mahady Dip, Md Golam Nur, Md Hasibul Hossain, Finn Snow, Nusrat Binta Hossain, Azadeh Mirabedini, Anita Quigley, Rajiv Padhye, Shadi Houshyar   +9 more
wiley   +1 more source

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F, Coluzzi, Flaminia, Corcione, A., Cuomo, A, Dauri, M, Leonardi, C, Melotti, Rm, Natoli, S, Romualdi, P, Savoia, G   +9 more
core   +2 more sources

Preoperative butorphanol and flurbiprofen axetil therapy attenuates remifentanil-induced hyperalgesia after laparoscopic gynaecological surgery: a randomized double-blind controlled trial.

British Journal of Anaesthesia, 2016
BACKGROUND Several studies indicate that remifentanil exposure may engender opioid-induced hyperalgesia. Butorphanol and flurbiprofen axetil are proposed as adjunctive analgesics for postoperative pain control.
L. Zhang, R. Shu, Q. Zhao, Y. Li, Y. Yu, G. Wang   +5 more
semanticscholar   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Gene Network Dysregulation in the Trigeminal Ganglia and Nucleus Accumbens of a Model of Chronic Migraine-Associated Hyperalgesia

Frontiers in Systems Neuroscience, 2018
The pharmacological agent nitroglycerin (NTG) elicits hyperalgesia and allodynia in mice. This model has been used to study the neurological disorder of trigeminovascular pain or migraine, a debilitating form of hyperalgesia.
Hyeonsoo Jeong, Laura S. Moye, Bruce R. Southey, Alvaro G. Hernandez, Isaac Dripps, Elena V. Romanova, Stanislav S. Rubakhin, Jonathan V. Sweedler, Amynah A. Pradhan, Sandra L. Rodriguez-Zas, Sandra L. Rodriguez-Zas   +10 more
doaj   +1 more source

Role of Gynecologic Findings in Interstitial Cystitis/Bladder Pain Syndrome: A Consensus

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To evaluate the role of gynecologic findings in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by reviewing current international guidelines and identifying relevant gynecologic co‐morbidities. Methods This consensus statement was developed through a systematic four‐phase process: (1) comprehensive literature review across ...
Marie E. Sullivan, Amr El Haraki, Anna Padoa, Katy Vincent, Kristene E. Whitmore, Mauro Cervigni   +5 more
wiley   +1 more source

Stem Cell Ophthalmology Treatment Study (SCOTS) for retinal and optic nerve diseases: a preliminary report

Neural Regeneration Research, 2015
In this report, we present the results of a single patient with optic neuropathy treated within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board approved clinical trial and is the largest ophthalmology stem cell
Jeffrey N Weiss, Steven Levy, Alexis Malkin   +2 more
doaj   +1 more source

Apoptotic gene expression in neuropathic pain [PDF]

, 2008
Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi, Carlo Fuccio, Catia Giordano, Dario Siniscalco, Francesco Rossi, Livio Luongo, Sabatino Maione   +6 more
core   +2 more sources

GRK6, a gatekeeper of visceral hyperalgesia

Brain, Behavior, and Immunity, 2009
Brief ...
Murga, Cristina, Mayor Menéndez, Federico   +1 more
openaire   +3 more sources

Sex Difference in Oxytocin-Induced Anti-Hyperalgesia at the Spinal Level in Rats with Intraplantar Carrageenan-Induced Inflammation

PLoS ONE, 2016
Previously, we demonstrated intrathecal administration of oxytocin strongly induced anti-hyperalgesia in male rats. By using an oxytocin-receptor antagonist (atosiban), the descending oxytocinergic pathway was found to regulate inflammatory hyperalgesia ...
L. Chow, Yuan-Hao Chen, Wan Wu, En-Pei Chang, E. Huang   +4 more
semanticscholar   +1 more source