Results 111 to 120 of about 100,236 (366)
Clinical characteristics of anti‐neurofascin 155 antibody‐positive autoimmune nodopathy in children
Pediatric anti‐neurofascin 155 antibody autoimmune nodopathy was uncommon, featuring distal limb weakness with sensory symptoms. Cerebrospinal fluid protein levels were elevated, and neuroimaging revealed nerve root thickening. As intravenous immunoglobulin was ineffective, early immunosuppressive therapy was recommended.
Liya Cui+13 more
wiley +1 more source
Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5a-reductase in the dorsal spinal cord of animals with neuropathic pain: effects of progesterone administration [PDF]
Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of steroidogenic regulatory proteins and enzymes in the spinal cord suggests that neurosteroids ...
Adler, Natalia Sol+6 more
core +2 more sources
The production and up-regulation of inflammatory mediators are contributing factors for the development and maintenance of neuropathic pain. In the present study, the post-treatment of synthetic 1,3,4 oxadiazole derivative (B3) for its neuroprotective ...
Muhammad Faheem+10 more
doaj +1 more source
Tramadol Induced Paradoxical Hyperalgesia
Opioids have been the mainstay analgesics for postoperative, cancerous, and chronic noncancerous pain. Common concerns regarding the use of opioids include the development of physical dependence and addiction. However, as a potential complication of opioid therapy, opioid-induced hyperalgesia (OIH) is often overlooked.
Seong Heon Lee+5 more
openaire +3 more sources
For the advancement of neuromorphic computing and bio‐integrated electronics, a dual‐stacked ITO/IGZO/ZrO2/Ti resistive random access memory (RRAM) device with oxygen vacancy engineering is demonstrated for reliable synaptic and nociceptive behavior. Gradual potentiation and depression, along with biologically inspired spike‐timing‐dependent plasticity
Seo‐Young Jo+4 more
wiley +1 more source
Pain Perception: Investigating Links Between Pain Transmission and CCK(+) Neurons, with Regard to the Opioid Crisis [PDF]
With dependence on opioids, such as codeine, morphine, and heroin, steadily increasing amongst the American public, the withdrawal symptoms associated with disuse are receiving much more attention.
Panesar, Sumeet, Tepper, Zachary
core +2 more sources
Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M+183 more
core +1 more source
Opioid-Induced Hyperalgesia (OIH)
Opioids are commonly used for pain control; however, they can cause hyperalgesia. The reason why this can happen is not known. The objective of this review was to describe the mechanisms, factors implicated, and drug modulation.The factors implicated in the development of opioid-induced hyperalgesia (OIH), such as duration of use, dose, and type of ...
Plinio da Cunha Leal+3 more
openaire +3 more sources
Opioid-induced hyperalgesia in chronic pain patients and the mitigating effects of gabapentin
Chronic pain patients receiving opioid drugs are at risk for opioid-induced hyperalgesia (OIH), wherein opioid pain medication leads to a paradoxical pain state.
N. Stoicea+6 more
semanticscholar +1 more source
Abstract A 6‐year‐old, male, entire Jack Russell terrier was referred for noise fear and subsequently diagnosed with underlying musculoskeletal discomfort. Significant improvements in the signs were reported by the clients by initially addressing the underlying discomfort using a combination of analgesia (1.7 mg/kg carprofen once a day), environmental ...
Beverley M. Wilson, Daniel S. Mills
wiley +1 more source