Results 111 to 120 of about 86,101 (292)

Is the temporomandibular joint affected by rheumatoid arthritis? A comparative investigation with knee arthritis in an experimental rat model

Journal of Anatomy, EarlyView.
Animals were sensitized with mBSA emulsified in CFA/IFA and subsequently received three intra‐articular injections of mBSA into either the TMJ or the knee (once per week). Mechanical hyperalgesia was assessed using electronic von Frey testing after arthritis establishment at 24 h or 7 days following the third intra‐articular injection.
Ana Carolina de Figueiredo Costa, Luane Macedo de Sousa, Delane Viana Gondim   +2 more
wiley   +1 more source

Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain [PDF]

, 2006
Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states.
Barrett, David, Chapman, Victoria, Jhaveri, Maulik, Kendall, David, Richardson, Denise   +4 more
core   +2 more sources

Psychophysical changes after total sleep deprivation and experimental muscle pain

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep disturbances exacerbate chronic pain, increase psychological load, and increase inflammation. Delayed onset muscle soreness (DOMS) mimics aspects of chronic pain, predominantly affecting peripheral pain mechanisms, while experimental sleep provocations have been shown to impact central pain mechanisms.
Emma Hertel, Elaxmi Sathiyalingam, Linea Pilgaard, Simone Juline Brommann, Rocco Giordano, Kristian Kjær‐Staal Petersen   +5 more
wiley   +1 more source

Central Sensitization in the Bladder Pain Syndrome [PDF]

, 2016
Introduction: Nociceptive hyper-excitability and Central Sensitization (CS), have been identified as responsible for maintaining pain in several chronic neuropathic pain conditions, among which Bladder pain syndrome (BPS). Aim of the present study was to
Cambieri, Chiara, Ceccanti, Marco, Cervigni, M, Gori, Mc, Inghilleri, Maurizio, Nasta, L, Onesti, Emanuela   +6 more
core  

Administration of the Sleep‐Promoting Neuromodulator Adenosine Into the Median Preoptic and Septal Region Produced Thermal Hyperalgesia

Journal of Sleep Research, EarlyView.
ABSTRACT Abundant clinical and preclinical evidence demonstrates that sleep and pain have bidirectional interactions. Sleep loss enhances pain perception and pain disrupts sleep. However, the exact neurobiological mechanisms through which sleep loss alters pain remain poorly understood.
Viviane S. Hambrecht‐Wiedbusch, Angelo V. Colmenero, Alejandra Mondino, Graciela Mentz, Steven E. Harte, Giancarlo Vanini   +5 more
wiley   +1 more source

Interictal widespread pressure hyperalgesia and aura: associations with vestibular migraine in a cross-sectional study

Frontiers in Neurology
BackgroundPatients with vestibular migraine (VM) exhibit higher levels of central sensitization and share similar disorder characteristics with migraine with vestibular symptoms (MwVS), except in terms of disability. These patients experience fluctuating
Toshihide Toriyama, Yoshiki Hanaoka, Tetsuyoshi Horiuchi   +2 more
doaj   +1 more source

Opioid-induced hyperalgesia after implantation of intrathecal morphine pump: a case report

, 2020
Sungryul Yoon, Rakmin Choi, Jae-Do Lee, Jong Chan Won, Bousung Lee, Kwanghaeng Lee, Dongseok Kim, Jaeyoung Yang   +7 more
openalex   +2 more sources

Review for "Genistein reverses the effect of 17β‐estradiol on exacerbating experimental occlusal interference‐induced chronic masseter hyperalgesia in ovariectomized rats"

, 2021

openalex   +1 more source

Molecular Aspects Involved in the Mechanisms of Bothrops jararaca Venom-Induced Hyperalgesia: Participation of NK1 Receptor and Glial Cells

Toxins
Accidents caused by Bothrops jararaca (Bj) snakes result in several local and systemic manifestations, with pain being a fundamental characteristic. The inflammatory process responsible for hyperalgesia induced by Bj venom (Bjv) has been studied; however,
Ariela de Oliveira Pedro Bom, Monique Dias-Soares, Raíssa Cristina Darroz Corrêa, Camila Lima Neves, Natalia Gabriele Hosch, Gabriela Gomes de Lucena, Camilla Garcia Oliveira, Rosana Lima Pagano, Marucia Chacur, Renata Giorgi   +9 more
doaj   +1 more source

Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]

, 2018
BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core