Results 111 to 120 of about 85,056 (307)

Apoptotic gene expression in neuropathic pain [PDF]

, 2008
Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi, Carlo Fuccio, Catia Giordano, Dario Siniscalco, Francesco Rossi, Livio Luongo, Sabatino Maione   +6 more
core   +2 more sources

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

Neurogastroenterology &Motility, EarlyView.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi, Rudolf Bauer, Thomas Efferth, Mohamed T. Khayyal, Michael Schemann, Gudrun Ulrich‐Merzenich, Christine Feinle‐Bisset   +6 more
wiley   +1 more source

Central Sensitization in the Bladder Pain Syndrome [PDF]

, 2016
Introduction: Nociceptive hyper-excitability and Central Sensitization (CS), have been identified as responsible for maintaining pain in several chronic neuropathic pain conditions, among which Bladder pain syndrome (BPS). Aim of the present study was to
Cambieri, Chiara, Ceccanti, Marco, Cervigni, M, Gori, Mc, Inghilleri, Maurizio, Nasta, L, Onesti, Emanuela   +6 more
core  

Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]

, 2005
It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Arham, A.Z., Hughes, D.I., Polgar, Erika, Todd, A.J.   +3 more
core   +2 more sources

Targeting pain and inflammation: A comparative study of photobiomodulation with 532 and 660 nm lasers in rats

Photochemistry and Photobiology, EarlyView.
This study evaluated the analgesic and inflammatory modulation effect of PBM using 660 nm (red) and 532 nm (green) lasers in a rat model of postoperative pain. Wistar rats underwent paw incision and received laser irradiation according to their groups.
Andréa Ribeiro Mattoso‐Câmara, Juliana Zampoli Boava Papini, Marcos Aurélio Teixeira, Denise Nami Fujii, Giovana Radomille Tofoli, Aguinaldo Silva Garcez   +5 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Molecular Aspects Involved in the Mechanisms of Bothrops jararaca Venom-Induced Hyperalgesia: Participation of NK1 Receptor and Glial Cells

Toxins
Accidents caused by Bothrops jararaca (Bj) snakes result in several local and systemic manifestations, with pain being a fundamental characteristic. The inflammatory process responsible for hyperalgesia induced by Bj venom (Bjv) has been studied; however,
Ariela de Oliveira Pedro Bom, Monique Dias-Soares, Raíssa Cristina Darroz Corrêa, Camila Lima Neves, Natalia Gabriele Hosch, Gabriela Gomes de Lucena, Camilla Garcia Oliveira, Rosana Lima Pagano, Marucia Chacur, Renata Giorgi   +9 more
doaj   +1 more source

Spinal Excitability in Patients with Painful Chronic Pancreatitis

Journal of Pain Research, 2023
Cecilie Siggaard Knoph,1,2 Rasmus Bach Nedergaard,1 Søren Schou Olesen,1,2 Louise Kuhlmann,1 Asbjørn Mohr Drewes1,2 1Center for Pancreatic Diseases & Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark;
Knoph CS, Nedergaard RB, Olesen SS, Kuhlmann L, Drewes AM   +4 more
doaj  

Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. [PDF]

, 2019
Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies.
Abrams, Gary, Chesney, Margaret, Conley, Yvette P, Kober, Kord M, Levine, Jon D, Melisko, Michelle, Miaskowski, Christine, Paul, Steven M, Schumacher, Mark, Topp, Kimberly   +9 more
core  

Age‐Related Variations of Corneal Sensitivity in Puppies Beagle Dogs

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To evaluate the evolution of corneal sensitivity in healthy beagle puppies during the first weeks of life, compare these results with adult corneal sensitivity, and determine the age at which adult corneal sensitivity levels are reached. Animals Studied Twelve puppies and five adult females.
Sabine Chahory, Célia Maringue, Pierre Huiban, Loïc Desquilbet   +3 more
wiley   +1 more source