Results 111 to 120 of about 98,039 (356)
Genetically‐targeted control of the spinal cord and peripheral nervous system
Journal of Intelligent Medicine, EarlyView.Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano +3 more
wiley +1 more source
Frontiers in Pharmacology, 2018 The present study investigates the possible anti-nociceptive effect of intraperitoneal (i.p.) honokiol: a phenolic compound originally isolated from Magnolia officinalis, in acute and chronic inflammatory pain models.
Sidra Khalid +8 more
doaj +1 more source
Nanomaterial‐Integrated 3D Biofabricated Structures for Advanced Biomedical Applications
Macromolecular Materials and Engineering, EarlyView.This review investigates the integration of nanomaterials into 3D biofabricated structures, highlighting the potential in tissue regeneration, wound healing, and cancer therapy. It discusses key techniques, including bioprinting and electrospinning, while addressing challenges such as biocompatibility, scalability, and regulatory barriers.
Mustafijur Rahman +9 more
wiley +1 more source
Amniotic-Fluid Ingestion Enhances\ud Morphine Analgesia During Morphine\ud Tolerance and Withdrawal in Rats [PDF]
, 1991 Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection. footshock, vaginal/cervical stimulation, and during late pregnancy.
Doerr, Jean C., Kristal, Dr. Mark B.
core
Purinergic mechanosensory transduction and visceral pain [PDF]
, 2009 In this review, evidence is presented to support the hypothesis that mechanosensory transduction occurs in tubes and sacs and can initiate visceral pain.
Burnstock, G
core +3 more sources
Tramadol Induced Paradoxical Hyperalgesia
Pain Physician, 2013 Opioids have been the mainstay analgesics for postoperative, cancerous, and chronic noncancerous pain. Common concerns regarding the use of opioids include the development of physical dependence and addiction. However, as a potential complication of opioid therapy, opioid-induced hyperalgesia (OIH) is often overlooked.
Seong Heon Lee +5 more
openaire +3 more sources
mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia
Molecular Pain, 2015 Chronic pain is a major public health problem with limited treatment options. Opioids remain a routine treatment for chronic pain, but extended exposure to opioid therapy can produce opioid tolerance and hyperalgesia.
B. Lutz +4 more
semanticscholar +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar +4 more
wiley +1 more source
Journal of Pain Research, 2020 Luopeng Zhao, 1, 2,* Lu Liu, 1, 3,* Xiaobai Xu, 1 Zhengyang Qu, 1 Yupu Zhu, 1 Zhijuan Li, 1 Jingxia Zhao, 2 Linpeng Wang, 1 Xianghong Jing, 3 Bin Li 1 1Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine, Capital ...
Zhao L +9 more
doaj
Animals, 2020 Chronic mixed pain and orthopedic dysfunction are the most frequently associated consequences of canine osteoarthritis (OA). An unmet need remains for safe and effective therapies for OA.
Enrico Gugliandolo +10 more
doaj +1 more source