Results 131 to 140 of about 84,168 (327)

Central Sensitization in the Bladder Pain Syndrome [PDF]

open access: yes, 2016
Introduction: Nociceptive hyper-excitability and Central Sensitization (CS), have been identified as responsible for maintaining pain in several chronic neuropathic pain conditions, among which Bladder pain syndrome (BPS). Aim of the present study was to
Cambieri, Chiara   +6 more
core  

Efficacy and safety of ozone injection into the intervertebral foramen for treating patients with chronic, intractable postherpetic neuralgia: a one-year follow-up study

open access: yesFrontiers in Neurology
IntroductionChronic intractable postherpetic neuralgia (PHN) is a significant sequel of herpes zoster and significantly impacts patients’ quality of life.
Jiang-Lin Wang   +10 more
doaj   +1 more source

Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1

open access: yesDrug Design, Development and Therapy, 2021
Qudong Lu,1 Yang Yang,1 Hengshuai Zhang,1 Cheng Chen,2 Jiang Zhao,1 Zhenxing Yang,1 Yi Fan,1 Longkun Li,1 Huan Feng,1 Jingzhen Zhu,1 Shanhong Yi1 1Department of Urology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, People’s ...
Lu Q   +10 more
doaj  

Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]

open access: yes, 2018
BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core  

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

open access: yesNeurogastroenterology &Motility, EarlyView.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi   +6 more
wiley   +1 more source

The effect of environment on post surgical overall well-being and pain sensitivity in an animal model [PDF]

open access: yes, 2016
With chronic post surgical pain affecting up to one third of patients undergoing surgeries and the price of treatment being astoundingly high there has been a transition in research to investigate and identify risk factors. Through identification of risk
Reddy, Archana
core   +1 more source

Transcutaneous Electrical Acustimulation Improves Gastroparesis Symptoms and Ameliorates Gastric Pace‐Making Activity in Patients With Diabetic Gastroparesis

open access: yesNeurogastroenterology &Motility, EarlyView.
Gastroparesis is common in patients with diabetes. However, treatment options for diabetic gastroparesis are limited. In our study, transcutaneous electrical acustimulation, a noninvasive method of delivering electrical stimulation via surface electrodes placed at certain acupuncture points with appropriate parameters was effective in treating the ...
Ying Zhu   +7 more
wiley   +1 more source

Plasma, Brain, and Spinal Cord Concentrations of Thiopental Associated with Hyperalgesia in the Rat [PDF]

open access: bronze, 1994
David P. Archer   +3 more
openalex   +1 more source

Pain Phenotype in Knee Osteoarthritis: Implications for Mechanism‐Based Therapy

open access: yesOrthopaedic Surgery, EarlyView.
The paper reported on the precise and individual treatment of knee osteoarthritis (KOA) pain based on its new classification, including Nociceptive Pain, Neuropathic Pain, and Nociplastic Pain. Tailored treatment recommendations for different types of pain through exploring potential mechanisms of pain in KOA are provided to achieve better clinical ...
Chenchang He   +5 more
wiley   +1 more source

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