SIRT2 overexpression decreases remifentanil-stimulated post-surgical hyperalgesia via microglia
, 2023 Wei Zhu, Zhengliang Ma
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Effective management of chronic lumbar back pain in five dogs using an erector spinae plane block
Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.Abstract This retrospective case series evaluates the use of the ultrasound‐guided erector spinae plane block for managing chronic lumbar pain in five dogs unresponsive to conventional systemic analgesia. Each patient received a bilateral erector spinae plane block at either the L2/L3 or L3/L4 level under general anaesthesia. The injectate consisted of
Nathalie Haslinger, Katrin Ertelt
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MoleculesScorpion envenomation is a public health issue in tropical and subtropical regions. Currently, there is limited data on the biological effects of Hottentotta judaicus scorpion venom (HjSV) in mammals.
Lara Haddad +7 more
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In vivo pathway of thermal hyperalgesia by intrathecal administration of α,β‐methylene ATP in mouse spinal cord: Involvement of the glutamate‐NMDA receptor system [PDF]
, 1999 Makoto Tsuda +2 more
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CCL17 Blockade by CCL17mAb/GSK-J4 Ameliorates Hyperalgesia in a Rat Model of Postoperative Pain
, 2023 Zhiyu Zhang +3 more
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British Journal of Pharmacology, Volume 183, Issue 3, Page 505-519, February 2026.Background and Purpose Riluzole, approved for amyotrophic lateral sclerosis (ALS), has a glutamate‐modulating profile favourable for mitigating opioid addiction. It reduces neuronal glutamate release and enhances glutamate reuptake, offering advantages over agents that only increase glutamate reuptake.
Ewa Galaj +7 more
wiley +1 more source
The effect of environment on post surgical overall well-being and pain sensitivity in an animal model [PDF]
, 2016 With chronic post surgical pain affecting up to one third of patients undergoing surgeries and the price of treatment being astoundingly high there has been a transition in research to investigate and identify risk factors. Through identification of risk
Reddy, Archana
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Cross-Talk of Toll-Like Receptor 5 and Mu-Opioid Receptor Attenuates Chronic Constriction Injury-Induced Mechanical Hyperalgesia through a Protein Kinase C Alpha-Dependent Signaling [PDF]
, 2021 Ching yun Chang +6 more
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Temporomandibular disorders and neck disability in individuals with cervical disc herniation
European Journal of Oral Sciences, Volume 134, Issue 1, February 2026.Abstract The primary aim of this study was to investigate the prevalence and severity of temporomandibular disorders (TMDs), and temporomandibular joint (TMJ) pain in patients with cervical disc herniation. The secondary aim was to investigate the relationship between neck disability, neck pain, sociodemographic factors, TMD, and TMJ pain.
Turgay Altunalan +3 more
wiley +1 more source
Does acetaminophen activate endogenous pain inhibition in chronic fatigue syndrome/fibromyalgia and rheumatoid arthritis? : a double-blind randomized controlled cross-over trial [PDF]
, 2013 Background: Although enhanced temporal summation (TS) and conditioned pain modulation (CPM), as characteristic for central sensitization, has been proved to be impaired in different chronic pain populations, the exact nature is still unknown. Objectives:
De Clerck, Luc +10 more
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