Results 151 to 160 of about 100,236 (366)

Trigeminal‐mediated headshaking in horses

Equine Veterinary Education, EarlyView.
Summary This clinical commentary is accompanying the manuscript on quantitative sensory testing and trigemino‐cervical thresholds in a Warmblood gelding affected by trigeminal‐mediated headshaking by Käfer‐Karrer et al. This new diagnostic method is promising for diagnosing a devastating disease which has an enormous impact on the horses welfare.
A. May, V. Franzen
wiley   +1 more source

Central Sensitization in the Bladder Pain Syndrome [PDF]

, 2016
Introduction: Nociceptive hyper-excitability and Central Sensitization (CS), have been identified as responsible for maintaining pain in several chronic neuropathic pain conditions, among which Bladder pain syndrome (BPS). Aim of the present study was to
Cambieri, Chiara, Ceccanti, Marco, Cervigni, M, Gori, Mc, Inghilleri, Maurizio, Nasta, L, Onesti, Emanuela   +6 more
core  

Efficacy of Combined Versus Supplementary Injection Techniques With Inferior Alveolar Nerve Block for Mandibular Molars With Symptomatic Irreversible Pulpitis: A Systematic Review and Network Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Achieving effective anaesthesia in mandibular molars with symptomatic irreversible pulpitis is challenging. Various strategies involving the inferior alveolar nerve block (IANB) have been investigated, such as supplementing with additional injections after IANB failure (SUPP) or combining injections with IANB as primary injections ...
Thanatpong Rujirawan, Sittichoke Osiri, Kanet Chotvorrarak   +2 more
wiley   +1 more source

Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]

, 2018
BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core  

Spinal cord SP release and hyperalgesia in monoarthritic rats: involvement of the GABA_B receptor system [PDF]

, 1994
Marzia Malcangio, Norman G. Bowery
openalex   +1 more source

Palmitoylethanolamide (PEA) Induces an Increase in Spleen Regulatory T Cells, Reduces CD8+ Cells and TNF‐α Levels in Target Organs, and Protects Mice From Graft‐Versus‐Host Disease‐Related Mortality Through PPAR Activation Without Compromising the Graft‐Versus‐Tumour Response

Immunology, EarlyView.
Effect of Palmitoylethanolamide (PEA) in a murine model of graft‐versus‐host disease (GVHD). Following an allogeneic transplant from C57BL/6J donors to BALB/c recipients, PEA treatment improved survival, alleviated clinical symptoms, and protected target organs in GVHD‐affected mice.
Bárbara Betônico Berg, Zara Desiree Tonidandel Campos, Gioconda Muniz Fiorenza Ruggio, Ana Flávia Santos Linhares, Bárbara Maximino Rezende, Stêfany Bruno de Assis Cau, Thiago Roberto Lima Romero, Mauro Martins Teixeira, Vanessa Pinho, Marina Gomes Miranda Castor   +9 more
wiley   +1 more source

Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol

Journal of Neuroendocrinology, EarlyView.
Abstract Evidence from both clinical and preclinical studies indicates that females experience a faster progression to drug addiction and more severe addiction‐related health effects compared with males. Estradiol (E2) plays a critical role in these sex differences.
Patricia Sinclair, Navdeep S. Dhanjal, E. Blair Towers, Wendy J. Lynch, Nadine Kabbani   +4 more
wiley   +1 more source

Dual-Acting Peripherally Restricted Delta/Kappa Opioid (CAV1001) Produces Antinociception in Animal Models of Sub-Acute and Chronic Pain

Journal of Pain Research, 2020
Craig T Hartrick,1 Dominic Poulin,2 Rebekka Molenaar,3 Allison Hartrick1 1Caventure Drug Discovery, Bloomfield Hills, MI, USA; 2Charles River Laboratories, Montreal, Canada; 3American Preclinical Services, Minneapolis, MN, USACorrespondence: Craig T ...
Hartrick CT, Poulin D, Molenaar R, Hartrick A   +3 more
doaj  

Does acetaminophen activate endogenous pain inhibition in chronic fatigue syndrome/fibromyalgia and rheumatoid arthritis? : a double-blind randomized controlled cross-over trial [PDF]

, 2013
Background: Although enhanced temporal summation (TS) and conditioned pain modulation (CPM), as characteristic for central sensitization, has been proved to be impaired in different chronic pain populations, the exact nature is still unknown. Objectives:
De Clerck, Luc, Grosemans, Sofie, Hans, Guy, Hermans, Linda, Ickmans, Kelly, Meeus, Mira, Moorkens, Greta, Nijs, Jo, Oderkerk, Jorinde, Struyf, Filip, Van Noesel, Kevin   +10 more
core   +1 more source

Plasma, Brain, and Spinal Cord Concentrations of Thiopental Associated with Hyperalgesia in the Rat [PDF]

, 1994
David P. Archer, Alastair Ewen, Sheldon H. Roth, Naaznin Samanani   +3 more
openalex   +1 more source