Results 151 to 160 of about 98,039 (356)

Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones [PDF]

, 2011
Peer reviewedPublisher ...
Davidson, Scott, Lear, Marissa, MacKenzie, Alasdair, Ross, Ruth Alexandra, Shanley, Lynne   +4 more
core   +4 more sources

EXPERIMENTAL HYPERALGESIA [PDF]

, 1980
Itobert H. LaMotte, Charles T. Robinson, Johann G. Thalhaitner, H. E. Torebjörk   +3 more
openalex   +1 more source

Behavioural and pharmacokinetic analysis of heroin and cocaine self‐administration: Effects of timeout on self‐administration and choice in male rats

British Journal of Pharmacology, EarlyView.
Background and Purpose Heroin and cocaine users tailor their dosage, frequency and administration route to maximise the drugs' effects or prevent withdrawal symptoms. Counterintuitively, preclinical self‐administration and choice experiments employ, almost invariably and regardless of the pharmacokinetic properties of the drug under examination, fixed ...
Ginevra D'Ottavio, Sara Pezza, Jacopo Modoni, Ingrid Reverte, Claudia Marchetti, Soami F. Zenoni, Silvana De Pirro, Daniela Maftei, Roberta Lattanzi, Giuseppe Esposito, Davide Ragozzino, Emiliano Merlo, Marco Venniro, Roberto Ciccocioppo, Fabio Fumagalli, Michele S. Milella, Aldo Badiani, Fernando Boix, Daniele Caprioli   +18 more
wiley   +1 more source

Contrasting alterations to synaptic and intrinsic properties in upper-cervical superficial dorsal horn neurons following acute neck muscle inflammation [PDF]

, 2014
Background: Acute and chronic pain in axial structures, like the back and neck, are difficult to treat, and have incidence as high as 15%. Surprisingly, most preclinical work on pain mechanisms focuses on cutaneous structures in the limbs and animal ...
Baba H, Belinda M Harris, Brett A Graham, David I Hughes, Melissa A Tadros, Philip S Bolton, Robert J Callister, Watson C   +7 more
core   +3 more sources

Contributions of synaptic energetic dysfunction by microtubule dynamics and microtubule‐based mitochondrial transport disorder to morphine tolerance

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Morphine is among the most powerful analgesic, but its long‐term use can cause tolerance. Synaptic ATP supply is critical for maintaining synaptic transmission. Microtubule‐based mitochondrial transport ensures synaptic energy supply.
Zheng Li, Jie Liu, Jie Ju, Xiaoling Peng, Wei Zhao, Jihao Ren, Xiaoqian Jia, Jihong Wang, Ye Tu, Feng Gao   +9 more
wiley   +1 more source

Stroke‐Homing Peptide‐DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps

Cell Proliferation, EarlyView.
SHp‐DNase1 combined with CRO inhibits NETs to alleviate intestinal IRI ABSTRACT Neutrophil extracellular traps (NETs) act as a vital first line of defence against tissue damage and pathogens, playing a significant role in improving diseases such as intestinal ischemia reperfusion injury (IRI).
Tingting Liu, Xinrong Lv, Qingshan Xu, Xiuting Qi, Shenghui Qiu, Yaqi Luan, Na Shen, Jing Cheng, Lan Jin, Tian Tian, Wentao Liu, Lai Jin, Zhongzhi Jia   +12 more
wiley   +1 more source

Plasma, Brain, and Spinal Cord Concentrations of Thiopental Associated with Hyperalgesia in the Rat [PDF]

, 1994
David P. Archer, Alastair Ewen, Sheldon H. Roth, Naaznin Samanani   +3 more
openalex   +1 more source

Phenotypic characteristics of diabetic neuropathic pain and factors associated in patients with Diabetes Mellitus‐type 2

Journal of Diabetes Investigation, EarlyView.
Four phenotypic groups of patients with diabetic neuropathic pain were found. Intensity, duration of pain, and the level of anxiety were the factors associated with belonging to the groups with worse characteristics. ABSTRACT Aims/Introduction To identify subgroups of patients with diabetic neuropathic pain according to their phenotypic characteristics
Helena De Sola, María Dueñas, Inmaculada Failde, Jenifer Palomo‐Osuna, Cristina Naranjo, Alejandro Salazar   +5 more
wiley   +1 more source

Spinal cord SP release and hyperalgesia in monoarthritic rats: involvement of the GABA_B receptor system [PDF]

, 1994
Marzia Malcangio, Norman G. Bowery
openalex   +1 more source

Introducing a specified on‐line multimodal prehabilitation approach for total knee replacement surgery candidates using data from the COVID‐19 pandemic: An exploratory field‐based, pre‐post, mixed methods implementation pilot study

Journal of Evaluation in Clinical Practice, Volume 31, Issue 3, April 2025.
Abstract Rationale Individuals waiting for total‐knee‐replacement surgery are at risk of developing morbidities and frailty which may affect their postoperative recovery. Multi‐modal prehabilitation could mitigate these unintentional effects. Aims and Objectives To implement and evaluate a specified online multi‐modal prehabilitation intervention in ...
Laura Garland, Jamie Gibson, Rashida Pickford, Gareth D. Jones   +3 more
wiley   +1 more source