Results 151 to 160 of about 104,030 (296)
Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.This review synthesizes current mechanistic and clinical evidence on IL‐6 inhibitors, particularly sarilumab and tocilizumab, concerning their effect on pain in RA. ABSTRACT Rheumatoid arthritis (RA) is an autoimmune systemic disease in which pain remains a major and often refractory symptom even after clinical remission of the disease.
Andrej Belančić +10 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
The Excelsatoxin A‐Receptor TMEM233 Modulates Nav1.8
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.TMEM233 is a largely uncharacterized transmembrane protein that enables the sensitivity of Nav1.8 to Excelasatoxin A, a naturally occurring peptide that can significantly reduce the fast inactivation of this ion channel (left) expressed in sensory neurons or different cell lines. Moreover, its presence enhances the use dependent block of Nav1.8 induced
George Oprita +13 more
wiley +1 more source
Opioid-induced Hyperalgesia: A Qualitative Systematic Review
Anesthesiology, 2006 M. Angst, J. D. Clark
semanticscholar +1 more source
Autonomic Arousal as a Mechanism of the Persistence of Nocebo Hyperalgesia.
Journal of Pain, 2017 B. Colagiuri, V. Quinn
semanticscholar +1 more source
Antinociceptive Effect of Vaccinium Myrtillus in Diabetic Rats
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2011 BACKGROUND AND OBJECTIVE: Diabetes mellitus in long-term accompanies with inappropriate complications like retinopathy and neuropathy and increased pain sensation due to neuropathy.
M Roghani, T Baluchnejadmojarad
doaj
Remifentanil tolerance and hyperalgesia: short‐term gain, long‐term pain?
Anaesthesia, 2016 E. Yu, D. H. Tran, S. W. Lam, M. Irwin
semanticscholar +1 more source
Opioid-induced hyperalgesia in patients after surgery: a systematic review and a meta-analysis.
British Journal of Anaesthesia, 2014 D. Fletcher, V. Martinez
semanticscholar +1 more source