Results 151 to 160 of about 85,056 (307)

The Prognostic Significance of LINC00638 in Lumbar Disc Herniation and Its Effect on Senescence of Nucleus Pulposus Cells

JOR SPINE, Volume 8, Issue 4, December 2025.
LINC00638 is down‐regulated in LDH patients serum, serving as a promising biomarker for LDH diagnosis and prognosis. Meanwhile, its overexpression can inhibit TNF‐α‐induced senescence of hNPCs, and LINC00638 regulates hNPCs senescence and LDH progression by modulating miR‐185‐5p. ABSTRACT Background Lumbar disc herniation (LDH) is a common degenerative
Zhen Wang, Jichen Liu, Yanhua Sun, Haishan Xu, Wei He, Shaowei Xu, Xijing He   +6 more
wiley   +1 more source

Stress-induced hyperalgesia: animal models and putative mechanisms [PDF]

, 2006
Hiroki Imbe
openalex   +1 more source

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

Prostaglandin levels, vaginal innervation, and cyst innervation as peripheral contributors to endometriosis-associated vaginal hyperalgesia in rodents

, 2016
Stacy L. McAllister, Barbra Giourgas, Elizabeth K. Faircloth, Emma Leishman, Heather B. Bradshaw, Eric R. Gross   +5 more
openalex   +1 more source

In vivo pathway of thermal hyperalgesia by intrathecal administration of α,β‐methylene ATP in mouse spinal cord: Involvement of the glutamate‐NMDA receptor system [PDF]

, 1999
Makoto Tsuda, Shinya Ueno, Kazuhide Inoue   +2 more
openalex   +1 more source

SIRT2 overexpression decreases remifentanil-stimulated post-surgical hyperalgesia via microglia

, 2023
Wei Zhu, Zhengliang Ma
openalex   +2 more sources

Investigations of urethral sphincter activity in mice with bladder hyperalgesia before and after drug administration of gabapentin. [PDF]

, 2019
PurposeThis study investigated the effect of gabapentin on lower urinary tract dysfunction focusing on urethral activities and cystitis-induced hyperalgesia in a mouse model of painful bladder syndrome/interstitial cystitis (PBS/IC). The electromyography&
Chang, Huiyi H, Chen, Jia-Jin, Choi, Hanul, Do, Rebecca, Ghoniem, Gamal, Lin, Ching-Ting, Yeh, Jih-Chao, Zi, Xiaolin   +7 more
core  

Nicotinic Receptors in the Medial Habenula to Interpeduncular Nucleus Pathway: Modulators of Reward, Aversion and Emotion

European Journal of Neuroscience, Volume 62, Issue 11, December 2025.
ABSTRACT The medial habenula–interpeduncular nucleus pathway is a highly conserved and densely innervated brain circuit known for its unique cholinergic transmission and exceptional expression of nicotinic acetylcholine receptors. This pathway plays a critical role in regulating motivational and emotional processes, particularly those related to ...
Maria Ciscato, Mathilde Chouvaeff, Alexandre Mourot   +2 more
wiley   +1 more source

CCL17 Blockade by CCL17mAb/GSK-J4 Ameliorates Hyperalgesia in a Rat Model of Postoperative Pain

, 2023
Zhiyu Zhang, Tian Zhang, Yijia Zhang, Yingxia Liang   +3 more
openalex   +2 more sources

Ketamine as an Analgesic Adjunct for Opioid-Induced Hyperalgesia in a Patient With a Sickle Cell Pain Episode [PDF]

, 2022
Michael R. Martinez, Emily H. Garmon, Garrett D. Starling, Monish Sheth   +3 more
openalex   +1 more source