Results 161 to 170 of about 85,056 (307)

The effect of environment on post surgical overall well-being and pain sensitivity in an animal model [PDF]

open access: yes, 2016
With chronic post surgical pain affecting up to one third of patients undergoing surgeries and the price of treatment being astoundingly high there has been a transition in research to investigate and identify risk factors. Through identification of risk
Reddy, Archana
core   +1 more source

Effects of methotrexate on Wnt/β‐catenin signaling and glial activation in temporomandibular joint arthritis in rats

open access: yesEuropean Journal of Oral Sciences, Volume 133, Issue 6, December 2025.
Abstract Rheumatoid arthritis is a chronic autoimmune disease that can affect the temporomandibular joint (TMJ) and cause pain. Methotrexate is widely used to control disease progression, but its effects on pain mechanisms are not fully understood. This study evaluated the antinociceptive effects of methotrexate on pain behavior, Wnt/β‐catenin pathway ...
Ana Carolina de Figueiredo Costa   +6 more
wiley   +1 more source

Quantitative sensory testing and trigeminocervical reflex thresholds in a Warmblood gelding affected by trigeminal‐mediated headshaking

open access: yesEquine Veterinary Education, Volume 37, Issue 12, Page e306-e311, December 2025.
Summary Diagnosing trigeminal‐mediated headshaking (TMHS) in horses primarily depends on identifying characteristic clinical signs such as headshaking and nasal irritation, along with excluding non‐trigeminal causes through additional diagnostic techniques, primarily imaging. Aside from somatosensory evoked potentials, which require anaesthesia and are
M. J. Käfer‐Karrer   +3 more
wiley   +1 more source

OP002 PAK4 inhibitor reduces remifentanil-induced postoperative hyperalgesia in rat [PDF]

open access: gold, 2023
Zhang Tianyao   +4 more
openalex   +1 more source

Trigeminal‐mediated headshaking in horses

open access: yesEquine Veterinary Education, Volume 37, Issue 12, Page 619-621, December 2025.
Summary This clinical commentary is accompanying the manuscript on quantitative sensory testing and trigemino‐cervical thresholds in a Warmblood gelding affected by trigeminal‐mediated headshaking by Käfer‐Karrer et al. This new diagnostic method is promising for diagnosing a devastating disease which has an enormous impact on the horses welfare.
A. May, V. Franzen
wiley   +1 more source

The effects of thalidomide and minocycline on taxol-induced hyperalgesia in rats

open access: green, 2008
Juan P. Cata   +2 more
openalex   +1 more source

Blood 1‐Deoxysphingolipid Levels Are Associated With Epidermal Denervation in Small Fiber Neuropathy

open access: yesJournal of the Peripheral Nervous System, Volume 30, Issue 4, December 2025.
ABSTRACT Background and Aims Dysfunctional sphingolipid metabolism leads to nerve fiber degeneration, particularly of small caliber Aδ and C fibers, in hereditary sensory and autonomic neuropathies. We aimed to investigate the association of blood 1‐deoxysphingolipid (1‐deoxySL) profiles and skin denervation in idiopathic small fiber neuropathy (SFN ...
Luisa Kreß   +5 more
wiley   +1 more source

Does acetaminophen activate endogenous pain inhibition in chronic fatigue syndrome/fibromyalgia and rheumatoid arthritis? : a double-blind randomized controlled cross-over trial [PDF]

open access: yes, 2013
Background: Although enhanced temporal summation (TS) and conditioned pain modulation (CPM), as characteristic for central sensitization, has been proved to be impaired in different chronic pain populations, the exact nature is still unknown. Objectives:
De Clerck, Luc   +10 more
core   +1 more source

Transcutaneous Electrical Acustimulation Improves Gastroparesis Symptoms and Ameliorates Gastric Pace‐Making Activity in Patients With Diabetic Gastroparesis

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 12, December 2025.
Gastroparesis is common in patients with diabetes. However, treatment options for diabetic gastroparesis are limited. In our study, transcutaneous electrical acustimulation, a noninvasive method of delivering electrical stimulation via surface electrodes placed at certain acupuncture points with appropriate parameters was effective in treating the ...
Ying Zhu   +7 more
wiley   +1 more source

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