Results 11 to 20 of about 86,101 (292)
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Molecular Pain, 2012 Background Our previous studies have shown that complete Freund’s adjuvant (CFA)-induced masseter inflammation and microinjection of the pro-inflammatory cytokine interleukin-1β (IL-1β) into the subnucleus interpolaris/subnucleus caudalis transition zone
Chai Bryan +4 more
doaj +1 more source
The Area of Secondary Hyperalgesia following Heat Stimulation in Healthy Male Volunteers: Inter- and Intra-Individual Variance and Reproducibility. [PDF]
PLoS ONE, 2016 INTRODUCTION:Clinical pain models can be applied when investigating basic physiologic pain responses in healthy volunteers. Several pain models exist; however, only few have been adequately validated.
Morten Sejer Hansen +5 more
doaj +1 more source
Molecular Mechanisms of Action of Undenatured Type II Collagen: Experimental and Clinical Evidence
Современная ревматология, 2022 In the treatment of joint diseases, including osteoarthritis (OA), the use of standardized extracts of undenatured type II collagen (UDC-II) is promising. It is known that UDC-II is involved in the regulation of innate and adaptive immunity (reduction of
O. A. Gromova +2 more
doaj +1 more source
Influence of Working Length on Post-operative Pain after Single or Two-visit Endodontic Treatment: A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Microorganisms in the cemental canal can lead to the development of periapical lesions and its mechanical removal by means of overinstrumentation may be more favourable for the success of endodontic treatment.
Alessandra Manchini Cardoso Tarallo +4 more
doaj +1 more source
Frontiers in Pain Research, 2022 The sensory experience of pain depends not only on the transmission of noxious information (nociception), but on the state of the body in a biological, psychological, and social milieu.
Qiliang Chen, Mary M. Heinricher
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 Well-established efficacy of botulinum neurotoxin type A (BoNT/A) in aesthetic dermatology and neuromuscular hyperactivity disorders relies on canonical interruption of acetylcholine neurotransmission at the neuromuscular junction at the site of the ...
Beatrice Oehler +7 more
doaj +1 more source
Journal of Pharmacological Sciences, 2013 Neuropathic pain induces allodynia and hyperalgesia. In the spared nerve injury (SNI) model, marked mechanical hyperalgesia is manifested as prolongation of the duration of paw withdrawal after pin stimulation.
Shohei Yamamoto +2 more
doaj +1 more source
Cells, 2021 The endocannabinoid system exerts an important role in pain processing and modulation. Modulation of the system with hydrolase inhibitors of anandamide (AEA) or 2-arachidonyl glycerol (2-AG) has proved effective in reducing migraine-like features in ...
Rosaria Greco +4 more
doaj +1 more source
Local and Widespread Pressure Pain Hyperalgesia Is Not Side Specific in Females with Unilateral Neck Pain that Can Be Reproduced during Passive Neck Rotation [PDF]
, 2019 Current evidence for widespread hyperalgesia in non-specific neck pain (NSNP) is unclear. It is currently recommended to group NSNP patients according to pain-provoking movements.
Escobio Prieto, Isabel +5 more
core +2 more sources