Results 11 to 20 of about 104,030 (296)
Opioid Induced Hyperalgesia [PDF]
Pain Medicine, 2015 To discuss the phenomenon of opioid induced hyperalgesia (OIH) and investigate the data and clinical recommendations available on this topic.A literature search on the topic of OIH was performed. Relevant studies pertaining to OIH were included in this review.Existing studies and reviews on the pathophysiology, diagnosis, and clinical management of OIH
Peter, Yi, Peter, Pryzbylkowski
openaire +3 more sources
Progress in Neurobiology, 2014 The importance of the modulation of pain by emotion is now widely recognised. In particular, stress and anxiety, depending on their nature, duration and intensity, can exert potent, but complex, modulatory influences typified by either a reduction or exacerbation of the pain state. Exposure to either acute or chronic stress can increase pain responding
Jennings, Elaine M. +3 more
openaire +4 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Contribution of Piezo2 to endothelium-dependent pain. [PDF]
, 2015 BackgroundWe evaluated the role of a mechanically-gated ion channel, Piezo2, in mechanical stimulation-induced enhancement of hyperalgesia produced by the pronociceptive vasoactive mediator endothelin-1, an innocuous mechanical stimulus-induced ...
Bogen, Oliver +3 more
core +2 more sources
Molecular Pain, 2012 Background Our previous studies have shown that complete Freund’s adjuvant (CFA)-induced masseter inflammation and microinjection of the pro-inflammatory cytokine interleukin-1β (IL-1β) into the subnucleus interpolaris/subnucleus caudalis transition zone
Chai Bryan +4 more
doaj +1 more source
Influence of Working Length on Post-operative Pain after Single or Two-visit Endodontic Treatment: A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Microorganisms in the cemental canal can lead to the development of periapical lesions and its mechanical removal by means of overinstrumentation may be more favourable for the success of endodontic treatment.
Alessandra Manchini Cardoso Tarallo +4 more
doaj +1 more source
Медицина болю, 2021 In the article, morphological changes of skin in the area of postoperative wound are displayed. It was discovered that continuous infusion of high-dose fentanyl (10–20 mcg/kg/h) for analgesia in the early postoperative period in children operated on for ...
Dmytro Dmytriiev +2 more
doaj +1 more source
Journal of Pharmacological Sciences, 2013 Neuropathic pain induces allodynia and hyperalgesia. In the spared nerve injury (SNI) model, marked mechanical hyperalgesia is manifested as prolongation of the duration of paw withdrawal after pin stimulation.
Shohei Yamamoto +2 more
doaj +1 more source
Biomedicines, 2023 The therapeutic potential of vortioxetine on mechanical hyperalgesia/allodynia was investigated in rats with streptozotocin-induced diabetes, and its possible mechanism of action was elucidated in this study.
Nazlı Turan Yücel +4 more
doaj +1 more source
Frontiers in Neuroscience, 2019 Central sensitization is a driving mechanism in many chronic pain patients, and manifests as hyperalgesia and allodynia beyond any apparent injury. Recent studies have demonstrated analgesic effects of motor cortex (M1) stimulation in several chronic ...
T. Meeker +5 more
semanticscholar +1 more source