Opioid Induced Hyperalgesia [PDF]
Pain Medicine, 2015 To discuss the phenomenon of opioid induced hyperalgesia (OIH) and investigate the data and clinical recommendations available on this topic.A literature search on the topic of OIH was performed. Relevant studies pertaining to OIH were included in this review.Existing studies and reviews on the pathophysiology, diagnosis, and clinical management of OIH
Peter, Yi, Peter, Pryzbylkowski
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The effect of psychological manipulations on the development of secondary hyperalgesia: a critical review [PDF]
PAIN Reports. As central sensitization is believed to contribute to persistent pain and psychological factors are increasingly acknowledged to play a role as well, the question arises of whether psychological factors can modulate the development of central ...
Elke Meyers +3 more
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Obstructive Sleep Apnea and Postoperative Hyperalgesia in Bariatric Surgery: A Prospective Observational Cohort Study [PDF]
Journal of Pain ResearchZhenyu Zhong,1,* Xian Lu,2,* Qian Zhang,1 Yueying Zhang1 1Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, People’s Republic of China; 2Department of Shanghai Key Laboratory of Psychotic
Zhong Z, Lu X, Zhang Q, Zhang Y
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Maresin 2, a Specialized Pro-Resolution Lipid Mediator, Reduces Pain and Inflammation Induced by Bothrops jararaca Venom in Mice [PDF]
ToxinsThe venom of Bothrops jararaca (BjV) induces intense and prolonged pain, which is not alleviated by antivenom, along with hemorrhage and inflammation.
Kassyo L. S. Dantas +11 more
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Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Sex Difference in Oxytocin-Induced Anti-Hyperalgesia at the Spinal Level in Rats with Intraplantar Carrageenan-Induced Inflammation. [PDF]
PLoS ONE, 2016 Previously, we demonstrated intrathecal administration of oxytocin strongly induced anti-hyperalgesia in male rats. By using an oxytocin-receptor antagonist (atosiban), the descending oxytocinergic pathway was found to regulate inflammatory hyperalgesia ...
Lok-Hi Chow +4 more
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Медицина болю, 2021 In the article, morphological changes of skin in the area of postoperative wound are displayed. It was discovered that continuous infusion of high-dose fentanyl (10–20 mcg/kg/h) for analgesia in the early postoperative period in children operated on for ...
Dmytro Dmytriiev +2 more
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Individual differences in pain sensitivity are associated with cognitive network functional connectivity following one night of experimental sleep disruption. [PDF]
, 2020 Previous work suggests that sleep disruption can contribute to poor pain modulation. Here, we used experimental sleep disruption to examine the relationship between sleep disruption-induced pain sensitivity and functional connectivity (FC) of cognitive ...
Finan, Patrick H +5 more
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Secondary hyperalgesia phenotypes exhibit differences in brain activation during noxious stimulation. [PDF]
PLoS ONE, 2015 Noxious stimulation of the skin with either chemical, electrical or heat stimuli leads to the development of primary hyperalgesia at the site of injury, and to secondary hyperalgesia in normal skin surrounding the injury.
Mohammad Sohail Asghar +5 more
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Frontiers in Pain Research, 2022 The sensory experience of pain depends not only on the transmission of noxious information (nociception), but on the state of the body in a biological, psychological, and social milieu.
Qiliang Chen, Mary M. Heinricher
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