Results 31 to 40 of about 16,227 (258)

Fear of pain potentiates nocebo hyperalgesia [PDF]

open access: yes, 2015
Per M Aslaksen,1 Peter S Lyby2 1Department of Psychology, Research Group for Cognitive Neuroscience, The Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway; 2Catosenteret Rehabilitation Center,
Aslaksen, Per M.   +3 more
core   +1 more source

Gabapentin Prevents Oxaliplatin-Induced Mechanical Hyperalgesia in Mice

open access: yesJournal of Pharmacological Sciences, 2014
.: Oxaliplatin, a platinum-based chemotherapy drug, frequently causes acute and chronic peripheral neuropathies including mechanical hyperalgesia. These adverse effects hinder anticancer therapy with the drug.
Masahiro Ohsawa   +5 more
doaj   +1 more source

Contact Heat Evoked Potentials Are Responsive to Peripheral Sensitization: Requisite Stimulation Parameters

open access: yesFrontiers in Human Neuroscience, 2020
The sensitizing effect of capsaicin has been previously characterized using laser and contact heat evoked potentials (LEPs and CHEPs) by stimulating in the primary area of hyperalgesia.
Lukas D. Linde   +12 more
doaj   +1 more source

Characterization of migraineurs presenting interictal widespread pressure hyperalgesia identified using a tender point count: a cross-sectional study

open access: yesThe Journal of Headache and Pain, 2017
Background Migraineurs exhibit pain hypersensitivity throughout the body during and between migraine headaches. Migraine is classified as a central sensitivity syndrome, typified by fibromyalgia showing widespread pressure hyperalgesia determined by a ...
Toshihide Toriyama   +2 more
doaj   +1 more source

Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats [PDF]

open access: yes, 2010
Chronic muscle pain of the neck, shoulder and low back is quite common and often related to a stressed condition. In this study we tried to make a model of long-lasting muscle mechanical hyperalgesia based on one type of stress, repeated cold stress (RCS)
Nasu, Teruaki   +2 more
core   +1 more source

Effects of conditioned pain modulation on Capsaicin-induced spreading muscle hyperalgesia in humans. [PDF]

open access: yes, 2023
OBJECTIVES Muscle pain can be associated with hyperalgesia that may spread outside the area of primary injury due to both peripheral and central sensitization. However, the influence of endogenous pain inhibition is yet unknown.
Siegenthaler, Andreas   +9 more
core   +1 more source

Differential involvement of reactive oxygen species in a mouse model of capsaicin-induced secondary mechanical hyperalgesia and allodynia

open access: yesMolecular Pain, 2017
Intradermally injected capsaicin induces secondary mechanical hyperalgesia and allodynia outside the primary (i.e., capsaicin-injected) site. This secondary mechanical hypersensitivity is attributed to central sensitization in which reactive oxygen ...
Jun-Ho La   +5 more
doaj   +1 more source

Intrathecal injections of non-peptide oxytocin receptor agonists, WAY 267,464 and TC OT 39, induce significant anti-hyperalgesia in both male and female rats with inflammatory pain [PDF]

open access: yesIranian Journal of Basic Medical Sciences
Objective(s): Hyperalgesia is a clinical condition related to chronic pain in which patients experience increased nociceptive sensitivity. Intrathecal oxytocin has been shown to induce significant anti-hyperalgesia in both rodents and humans. However, in
Lok-Hi Chow   +4 more
doaj   +1 more source

Thermo-Sensitive TRP Channels: Novel Targets for Treating Chemotherapy-Induced Peripheral Pain

open access: yesFrontiers in Physiology, 2017
Abnormal Ca2+ channel physiology, expression levels, and hypersensitivity to heat have been implicated in several pain states following treatment with chemotherapeutic agents.
Mustafa Nazıroğlu, Nady Braidy
doaj   +1 more source

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

open access: yes, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Geisslinger, Gerd   +17 more
core   +1 more source

Home - About - Disclaimer - Privacy