Results 31 to 40 of about 100,236 (366)

Local and Widespread Pressure Pain Hyperalgesia Is Not Side Specific in Females with Unilateral Neck Pain that Can Be Reproduced during Passive Neck Rotation [PDF]

, 2019
Current evidence for widespread hyperalgesia in non-specific neck pain (NSNP) is unclear. It is currently recommended to group NSNP patients according to pain-provoking movements.
Escobio Prieto, Isabel, Heredia Rizo, Alberto Marcos, Luque Carrasco, Antonio, Madeleine, Pascal, Oliva Pascual-Vaca, Ángel, Piña-Pozo, Fernando   +5 more
core   +2 more sources

Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats

BMC Neuroscience, 2019
Peripheral diabetic neuropathy can be painful and its symptoms include hyperalgesia, allodynia and spontaneous pain. Hydrogen sulfide (H2S) is involved in diabetes-induced hyperalgesia and allodynia.
J. Roa-Coria, J. B. Pineda-Farías, P. Barragán-Iglesias, G. Quiñonez-Bastidas, Ángel Zúñiga-Romero, J. C. Huerta-Cruz, J. G. Reyes-García, F. Flores-Murrieta, V. Granados-Soto, H. Rocha-González   +9 more
semanticscholar   +1 more source

Rationale for analgesia to prevent postoperative hyperalgesia in children, according to the morphological study of skin in the wound

Медицина болю, 2021
In the article, morphological changes of skin in the area of postoperative wound are displayed. It was discovered that continuous infusion of high-dose fentanyl (10–20 mcg/kg/h) for analgesia in the early postoperative period in children operated on for ...
Dmytro Dmytriiev , Oleksandr Marchuk , Olena Kovalchuk   +2 more
doaj   +1 more source

Supraspinal contributions to hyperalgesia [PDF]

Proceedings of the National Academy of Sciences, 1999
Tissue injury is associated with sensitization of nociceptors and subsequent changes in the excitability of central (spinal) neurons, termed central sensitization. Nociceptor sensitization and central sensitization are considered to underlie, respectively, development of primary hyperalgesia and secondary hyperalgesia. Because central
M. O. Urban, G.F. Gebhart
openaire   +3 more sources

Role of Nociceptor Toll-like Receptor 4 (TLR4) in Opioid-Induced Hyperalgesia and Hyperalgesic Priming

Journal of Neuroscience, 2019
In addition to analgesia, opioids produce opioid-induced hyperalgesia (OIH) and neuroplasticity characterized by prolongation of inflammatory-mediator-induced hyperalgesia (hyperalgesic priming).
Dionéia Araldi, O. Bogen, P. Green, J. Levine   +3 more
semanticscholar   +1 more source

Characterization of migraineurs presenting interictal widespread pressure hyperalgesia identified using a tender point count: a cross-sectional study

The Journal of Headache and Pain, 2017
Background Migraineurs exhibit pain hypersensitivity throughout the body during and between migraine headaches. Migraine is classified as a central sensitivity syndrome, typified by fibromyalgia showing widespread pressure hyperalgesia determined by a ...
Toshihide Toriyama, Tetsuyoshi Horiuchi, Kazuhiro Hongo   +2 more
doaj   +1 more source

Dexmedetomidine Alleviates Microglia-Induced Spinal Inflammation and Hyperalgesia in Neonatal Rats by Systemic Lipopolysaccharide Exposure

Frontiers in Cellular Neuroscience, 2021
Noxious stimulus and painful experience in early life can induce cognitive deficits and abnormal pain sensitivity. As a major component of the outer membrane of gram-negative bacteria, lipopolysaccharide (LPS) injection mimics clinical symptoms of ...
Wen Wen, Wen Wen, Xingrui Gong, Hoiyin Cheung, Yanyan Yang, Yanyan Yang, Meihua Cai, Meihua Cai, Jijian Zheng, Jijian Zheng, Xiaoping Tong, Xiaoping Tong, Mazhong Zhang, Mazhong Zhang   +13 more
doaj   +1 more source

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico, Becker, Wiebke, Brenneis, Christian, Coste, Ovidiu, Geisslinger, Gerd, Nusing, Rolf M., Popp, Laura, Schmidt, Ronald, Scholich, Klaus   +8 more
core   +1 more source

Central Amygdala Circuits Mediate Hyperalgesia in Alcohol-Dependent Rats

Journal of Neuroscience, 2018
Alcohol withdrawal symptoms contribute to excessive alcohol drinking and relapse in alcohol-dependent individuals. Among these symptoms, alcohol withdrawal promotes hyperalgesia, but the neurological underpinnings of this phenomenon are not known ...
E. Avegno, Thomas D. Lobell, Christy A. Itoga, Brittni B. Baynes, Annie M. Whitaker, Marcus M. Weera, Scott Edwards, J. Middleton, N. Gilpin   +8 more
semanticscholar   +1 more source

Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors

Brazilian Journal of Medical and Biological Research, 2001
The aim of the present study was to determine if phenobarbital affects the nociception threshold. Systemic (1-20 mg/kg) phenobarbital administration dose dependently induced hyperalgesia in the tail-flick, hot-plate and formalin tests in rats and in the ...
C.M. Yokoro, S.M.S. Pesquero, R.M.M. Turchetti-Maia, J.N. Francischi, M.A.K.F. Tatsuo   +4 more
doaj   +1 more source