Results 41 to 50 of about 98,039 (356)
Frontiers in Integrative Neuroscience, 2019 BackgroundAcupuncture is used to reduce chronic musculoskeletal pain. The common mechanism underlying these types of pain are peripheral and/or central sensitization.
Zhen Zheng +4 more
doaj +1 more source
Morphine-induced hyperalgesia involves mu opioid receptors and the metabolite morphine-3-glucuronide
Scientific Reports, 2017 Opiates are potent analgesics but their clinical use is limited by side effects including analgesic tolerance and opioid-induced hyperalgesia (OIH). The Opiates produce analgesia and other adverse effects through activation of the mu opioid receptor (MOR)
Laurie-Anne Roeckel +10 more
semanticscholar +1 more source
Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat
Cell Reports, 2016 The naked mole-rat is a subterranean rodent lacking several pain behaviors found in humans, rats, and mice. For example, nerve growth factor (NGF), an important mediator of pain sensitization, fails to produce thermal hyperalgesia in naked mole-rats. The
Damir Omerbašić +9 more
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Stress-related alterations of visceral sensation: animal models for irritable bowel syndrome study. [PDF]
, 2011 Stressors of different psychological, physical or immune origin play a critical role in the pathophysiology of irritable bowel syndrome participating in symptoms onset, clinical presentation as well as treatment outcome.
Larauche, Muriel +2 more
core +2 more sources
Nocebo hyperalgesia and the startle response [PDF]
Neuroscience, 2016 The literature on the effects of nocebo on pain is sparse. The present experimental study investigated whether suggestions of nocebo hyperalgesia modified the startle response and whether increased startle contributed to the nocebo hyperalgesic effect.A design with four groups was employed; the participants were randomized into either a placebo group ...
Aslaksen, Per M. +3 more
openaire +4 more sources
Scientific Reports, 2017 Endometriosis is an incurable gynecological disorder characterized by debilitating pain and the establishment of innervated endometriosis lesions outside the uterus. In a preclinical mouse model of endometriosis we demonstrated overexpression of the PGE2-
E. Greaves +7 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2023 Intraoperative remifentanil infusion may paradoxically induce post-surgical hyperalgesia. Dexmedetomidine reportedly reduces opioid-induced hyperalgesia. Nalmefene selectively reverses several side-effects of opioids without impairing analgesia.
Zhen Jia +17 more
doaj +1 more source
Local and Widespread Pressure Pain Hyperalgesia Is Not Side Specific in Females with Unilateral Neck Pain that Can Be Reproduced during Passive Neck Rotation [PDF]
, 2019 Current evidence for widespread hyperalgesia in non-specific neck pain (NSNP) is unclear. It is currently recommended to group NSNP patients according to pain-provoking movements.
Escobio Prieto, Isabel +5 more
core +2 more sources
Journal of Neuroscience, 2016 The complement cascade is a principal component of innate immunity. Recent studies have underscored the importance of C5a and other components of the complement system in inflammatory and neuropathic pain, although the underlying mechanisms are largely ...
L. Shutov +8 more
semanticscholar +1 more source
Optoelectronic Devices for In‐Sensor Computing
Advanced Materials, EarlyView.The raw data obtained directly from sensors in the noisy analogue domain is often unstructured, which lacks a predefined format or organization and does not conform to a specific data model. Optoelectronic devices for in‐sensor visual processing can integrate perception, memory, and processing functions in the same physical units, which can compress ...
Qinqi Ren +7 more
wiley +1 more source