Results 31 to 40 of about 925 (106)

Hyperbaric oxygen therapy for the treatment of hypoxic/ischemic injury upon perinatal asphyxia—are we there yet?

open access: yesFrontiers in Neurology
Birth asphyxia and its main sequel, hypoxic-ischemic encephalopathy, are one of the leading causes of children’s deaths worldwide and can potentially worsen the quality of life in subsequent years.
Damian Mielecki   +2 more
doaj   +1 more source

Effect of hyperbaric oxygen and ozone preconditioning on oxidative/nitrosative stress induced by tourniquet ischemia/reperfusion in rat skeletal muscle

open access: yesActa Orthopaedica et Traumatologica Turcica, 2020
Objectives: The aim of the study was to investigate the effect of hyperbaric oxygen-preconditioning (HBO-PC) and ozone-preconditioning (O3-PC) on oxidative/nitrosative stress induced by tourniquet ischemia/reperfusion (I/R) in rat skeletal muscle ...
Kenan Koca   +5 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz   +10 more
wiley   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying   +12 more
wiley   +1 more source

Neuromodulation Techniques in Chronic Cerebral Hypoperfusion: Mechanisms and Therapeutic Advances

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Chronic cerebral hypoperfusion drives vascular cognitive impairment through neurovascular dysfunction, white matter injury, neuroinflammation, oxidative stress and synaptic network failure. Neuromodulation may offer a multi‐target strategy to restore plasticity, improve functional connectivity and support cognitive recovery. ABSTRACT Background Chronic
Chenye Qiao   +7 more
wiley   +1 more source

Transcatheter Intra‐Arterial Delivery of a Platelet‐Derived Extracellular Vesicle‐Enriched Preparation for Attenuating Skeletal Muscle Ischaemia‐Reperfusion Injury in a Rodent Forelimb Model

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) are non‐replicating, lipid membrane‐bound nanoparticles released by most eukaryotic cells into the extracellular space. When derived from platelets, a subset of EVs can exhibit remarkable anti‐inflammatory and antioxidant properties, making them attractive candidates to attenuate sterile inflammatory states such as
Omar A. Selim   +4 more
wiley   +1 more source

Oxygen Therapy for Intracranial Hemorrhage

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Oxygen therapies confer neuroprotective effects on patients with intracranial hemorrhage through mechanisms such as anti‐inflammation, reduction of cerebral edema and neuronal death, and enhancement of aerobic metabolism. Clinical evidence suggests that oxygen therapy may improve neurological recovery and decrease mortality in patients with ...
Qiqi Shi   +10 more
wiley   +1 more source

Intracerebral Hemorrhage: Advances, Knowledge Gaps, and Future Directions

open access: yesMedComm, Volume 6, Issue 11, November 2025.
This review provides a comprehensive synthesis of current research on the epidemiology, pathophysiological mechanisms, imaging characteristics, treatment delays, clinical management strategies, neural repair, and prognostic prediction of intracerebral hemorrhage (ICH).
Tao Liu   +6 more
wiley   +1 more source

Adaptations to hypoxia in the vertebrate retina

open access: yesThe Journal of Physiology, Volume 603, Issue 21, Page 6517-6531, November 1, 2025.
Abstract figure legend Most animals, including mammals, are susceptible to the damaging effects of hypoxia or ischaemia, where the result is neuronal cell death in the brain. By contrast, some neurons of the mammalian retina are less sensitive to hypoxia. In both brain and retina, neurons may survive if first preconditioned with ischaemia.
Michael G. Jonz
wiley   +1 more source

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