Genetics of Hypercholesterolemia: Comparison Between Familial Hypercholesterolemia and Hypercholesterolemia Nonrelated to LDL Receptor [PDF]
Frontiers in Genetics, 2020 Severe hypercholesterolemia (HC) is defined as an elevation of total cholesterol (TC) due to the increase in LDL cholesterol (LDL-C) >95th percentile or 190 mg/dl.
Estíbaliz Jarauta +9 more
doaj +6 more sources
Prevalence of Severe Hypercholesterolemia and Familial Hypercholesterolemia Phenotype in Patients with Acute Coronary Syndrome. [PDF]
Medicina (Kaunas)Background and Objectives: Atherosclerotic cardiovascular disease is one of the most common causes of death and disability around the world. Hypercholesterolemia is an established and widely prevalent risk factor; however, the prevalence of severe ...
Aliošaitienė U +6 more
europepmc +2 more sources
Correlates of Untreated Hypercholesterolemia in Older Adults: A Community-Based Household Survey in China. [PDF]
PLoS ONE, 2015 Hypercholesterolemia is common in older adults and less treated, but little is known about correlates of untreated hypercholesterolemia. Using a standard interview method we examined a random sample of 7,572 participants aged ≥60 years in a community ...
Zhi Hu +4 more
doaj +7 more sources
The Histomorphological Study on Testicular Cells of Hypercholesterolemia Rats Treated by Polysaccharides of Sea Cucumber, Holothuria nobilis [PDF]
E3S Web of Conferences, 2020 Hypercholesterolemia is a condition characterized by the presence of high levels of plasma cholesterol. This study aims to determine the morphological change of testicular cells in hypercholesterolemia rats treated by polysaccharides of sea cucumber ...
Ulhusna Fitrah A. +2 more
doaj +1 more source
Familial Hypercholesterolemia [PDF]
Cardiology Clinics, 2015 Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol ...
Victoria Enchia, Bouhairie +1 more
openaire +3 more sources
Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues
Anais da Academia Brasileira de Ciências, 2022 Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol levels, a clinical condition called hypercholesterolemia.
MATHEUS S. RODRIGUES +10 more
doaj +1 more source
A comprehensive metabolic profiling of the metabolically healthy obesity phenotype
Lipids in Health and Disease, 2020 Background The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as “metabolically healthy obese” (MHO).
Vibeke H. Telle-Hansen +4 more
doaj +1 more source
JMIR Human Factors, 2022 BackgroundFamilial hypercholesterolemia, a prevalent genetic disorder, remains significantly underdiagnosed in the United States.
Hana Bangash +5 more
doaj +1 more source
Jurnal Soeropati, 2022 Hypertension is a condition in which a person experiences an increase in systolic blood pressure of more or equal to 140 mmHg and diastolic blood pressure of more or equal to 90 mmHg.
Yauwan Tobing Lukiyono +4 more
doaj +1 more source
The effects of cholesterol accumulation on Achilles tendon biomechanics: A cross-sectional study.
PLoS ONE, 2021 Familial hypercholesterolemia, a common genetic metabolic disorder characterized by high cholesterol levels, is involved in the development of atherosclerosis and other preventable diseases.
Kipling Squier +6 more
doaj +1 more source