Results 1 to 10 of about 199,665 (351)

Predictive value of systemic inflammation response index for atherosclerotic cardiovascular disease risk in patients with hypercholesterolemia: a machine learning study with dual-cohort validation [PDF]

Lipids in Health and Disease
Background Residual cardiovascular risk persists in patients with hypercholesterolemia despite lipid-lowering therapy, underscoring the importance of inflammation in ASCVD development.
Yu Chen, Weikang Huang, Shihan Zhao, Zhuoqi Ge, Yan Liu, Ruibing Huang, Dongmei Li, Qing Xu, Xingzhen Long, Kai Wei, Qi Chen, Changcheng Sheng, Cailin Tang, Xue Bai   +13 more
doaj   +2 more sources

Long-Term Risk of Atherosclerotic Cardiovascular Disease in US Adults With the Familial Hypercholesterolemia Phenotype [PDF]

Circulation, 2016
Sarah D De Ferranti, Holly C Gooding, John T Wilkins   +2 more
exaly   +2 more sources

Thirty percent of children and young adults with familial hypercholesterolemia treated with statins have adherence issues

American Journal of Preventive Cardiology, 2021
Objective: To assess adherence to lipid lowering therapy (LLT), reasons for poor adherence, and achievement of LDL-C treatment goals in children and young adults with familial hypercholesterolemia (FH).
Gisle Langslet, Anja K. Johansen, Martin P. Bogsrud, Ingunn Narverud, Hilde Risstad, Kjetil Retterstøl, Kirsten B. Holven   +6 more
doaj   +1 more source

Alterations of ileal mucosa-associated microbiota in hypercholesterolemia patients

Heliyon, 2023
Many metabolic diseases have been demonstrated to be associated with changes in the microbiome. However, no studies have yet been conducted to examine the characteristics of the mucosal microbiota of patients with hypercholesterolemia.
Jia Li, Jinxia Ma, Weihua Wang, Haitao Du, Shuai Tang, Yi Li, Wenya Zhu, Ru Zhang, Jun Wan   +8 more
doaj   +1 more source

Familial Hypercholesterolemia [PDF]

Cardiology Clinics, 2015
Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol ...
Victoria Enchia, Bouhairie, Anne Carol, Goldberg   +1 more
openaire   +3 more sources

The Histomorphological Study on Testicular Cells of Hypercholesterolemia Rats Treated by Polysaccharides of Sea Cucumber, Holothuria nobilis [PDF]

E3S Web of Conferences, 2020
Hypercholesterolemia is a condition characterized by the presence of high levels of plasma cholesterol. This study aims to determine the morphological change of testicular cells in hypercholesterolemia rats treated by polysaccharides of sea cucumber ...
Ulhusna Fitrah A., Wresdiyati Tutik, Winarto Adi   +2 more
doaj   +1 more source

Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues

Anais da Academia Brasileira de Ciências, 2022
Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol levels, a clinical condition called hypercholesterolemia.
MATHEUS S. RODRIGUES, JULIA N. MARTINS, GABRIELA C. DE PAULA, LIGIA M. VENTURINI, GUSTAVO DE B. SILVEIRA, EMÍLIO L. STRECK, JOSIANI BUDNI, RICARDO A. MACHADO DE ÁVILA, ANDREZA F. DE BEM, PAULO C.L. SILVEIRA, JADE DE OLIVEIRA   +10 more
doaj   +1 more source

Web-Based Tool (FH Family Share) to Increase Uptake of Cascade Testing for Familial Hypercholesterolemia: Development and Evaluation

JMIR Human Factors, 2022
BackgroundFamilial hypercholesterolemia, a prevalent genetic disorder, remains significantly underdiagnosed in the United States.
Hana Bangash, Ahmed Makkawy, Justin H Gundelach, Alexandra A Miller, Kimberly A Jacobson, Iftikhar J Kullo   +5 more
doaj   +1 more source

A comprehensive metabolic profiling of the metabolically healthy obesity phenotype

Lipids in Health and Disease, 2020
Background The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as “metabolically healthy obese” (MHO).
Vibeke H. Telle-Hansen, Jacob J. Christensen, Gulla Aase Formo, Kirsten B. Holven, Stine M. Ulven   +4 more
doaj   +1 more source

Correlates of Untreated Hypercholesterolemia in Older Adults: A Community-Based Household Survey in China. [PDF]

PLoS ONE, 2015
Hypercholesterolemia is common in older adults and less treated, but little is known about correlates of untreated hypercholesterolemia. Using a standard interview method we examined a random sample of 7,572 participants aged ≥60 years in a community ...
Zhi Hu, M Justin Zaman, Jingjing Wang, Janet L Peacock, Ruoling Chen   +4 more
doaj   +1 more source