Results 21 to 30 of about 182,065 (262)

Young women with familial hypercholesterolemia have higher LDL-cholesterol burden than men: Novel data using repeated measurements during 12-years follow-up

Atherosclerosis Plus, 2023
Background and aims: The concentration and the duration of exposure to low-density lipoprotein cholesterol (LDL-C) (LDL-C burden) is an important determinant of risk for cardiovascular disease and thresholds has recently been estimated.
Anja K. Johansen, Martin P. Bogsrud, Jacob J. Christensen, Amanda Rundblad, Ingunn Narverud, Stine Ulven, Gisle Langslet, Kjetil Retterstøl, Kirsten B. Holven   +8 more
doaj  

Hormonal Factors Moderate the Associations Between Vascular Risk Factors and White Matter Hyperintensities [PDF]

arXiv, 2022
Objective: To examine the moderation effects of hormonal factors on the associations between vascular risk factors and white matter hyperintensities (WMH) in men and women, separately. Methods: WMH were automatically segmented and quantified in the UK Biobank dataset (N = 18,294). Generalised linear models were applied to examine 1) the main effects of
arxiv  

Familial hypercholesterolemia: The Italian Atherosclerosis Society Network (LIPIGEN) [PDF]

, 2017
Primary dyslipidemias are a heterogeneous group of disorders characterized by abnormal levels of circulating lipoproteins. Among them, familial hypercholesterolemia is the most common lipid disorder that predisposes for premature cardiovascular disease ...
Angelico, F., Arca, M, Averna, M., Bertolini, S, Calandra, S, Casula, M, Catapano, Al, Cefalù, Ab, Del Ben, M., Lipigen, Group, Maranghi, M, Montali, A., Noto, D, Tarugi, P.   +13 more
core   +1 more source

Familial hypercholesterolemia: a systematic review of guidelines on genetic testing and patient management [PDF]

, 2017
BACKGROUND: Familial hypercholesterolemia (FH) is an autosomal-dominant hereditary disorder of lipid metabolism that causes lifelong exposure to increased LDL levels resulting in premature coronary heart disease and, if untreated, death.
Baccolini, Valentina, D'Andrea, Elvira, De Vito, Corrado, Massimi, Azzurra, Migliara, Giuseppe, Rosso, Annalisa, Villari, Paolo   +6 more
core   +2 more sources

Antioxidants level in serum of patients with high cholesterol [PDF]

مجلة التربية والعلم, 2008
This study included evaluation the relationship between cholesterol and antioxidants level in the human with hypercholesterolemia . Blood of 33 samples were collected from patients with hypercholesterolemia 18 male and 15 female with age ranging between (
Ameera Hamdoon
doaj   +1 more source

Analysis of chronic diseases progression using stochastic modeling [PDF]

arXiv, 2021
This book handles the fatty liver disease from the bio-statistical point of view . It discusses the disease process in the simple general form of health-disease-death multi-states model . Continuous Time Markov Chains are used to estimate the rate transition matrix utilizing the MLE and Quasi-Newton formula , once obtained , the probability transition ...
arxiv  

Screening for familial hypercholesterolaemia in primary care: Time for general practice to play its part [PDF]

, 2018
Fifty per cent of first-degree relatives of index cases with familial hypercholesterolemia (FH) inherit the disorder. Despite cascade screening being the most cost-effective method for detecting new cases, only a minority of individuals with FH are ...
Brett, Tom, Gidding, Samuel, Qureshi, Nadeem, Watts, Gerald F   +3 more
core   +3 more sources

Alterations of ileal mucosa-associated microbiota in hypercholesterolemia patients

Heliyon, 2023
Many metabolic diseases have been demonstrated to be associated with changes in the microbiome. However, no studies have yet been conducted to examine the characteristics of the mucosal microbiota of patients with hypercholesterolemia.
Jia Li, Jinxia Ma, Weihua Wang, Haitao Du, Shuai Tang, Yi Li, Wenya Zhu, Ru Zhang, Jun Wan   +8 more
doaj  

Ezetimibe therapy: mechanism of action and clinical update. [PDF]

, 2012
The lowering of low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy in the primary and secondary prevention of cardiovascular events.
Dayspring, Thomas D, Phan, Binh An P, Toth, Peter P   +2 more
core   +1 more source

Menopausal Impact on the Association Between Thyroid Dysfunction and Lipid Profiles: A Cross-Sectional Study

Frontiers in Endocrinology, 2022
BackgroundBoth dyslipidemia and thyroid dysfunction have a high prevalence rate and are important risk factors for cardiovascular diseases. However, the relationship between blood lipids and thyroid dysfunction is still controversial.
Yutong Han, Chuyuan Wang, Lihui Zhang, Jun Zhu, Mei Zhu, Yongze Li, Di Teng, Weiping Teng, Zhongyan Shan   +8 more
doaj   +1 more source