The Role of Natural Products in Pharmacotherapy of Alzheimer’s Disease [PDF]
Alzheimer’s disease is characterized by forgetfulness, disturbance in memory and loss of mental abilities. The final outcome of the disease is loss of personality and intellectual functions.
Singh, Amrit Pal
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Successful therapies for Alzheimer's disease: why so many in animal models and none in humans? [PDF]
Peering into the field of Alzheimer's disease (AD), the outsider realizes that many of the therapeutic strategies tested (in animal models) have been successful.
Cedazo-Mínguez, Ángel +1 more
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Hypericum sp.: essential oil composition and biological activities [PDF]
Phytochemical composition of Hypericum genus has been investigated for many years. In the recent past, studies on the essential oils (EO) of this genus have been progressing and many of them have reported interesting biological activities. Variations in
A Baruah +158 more
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Secondary Metabolites of Hypericum leptophyllum Hochst., an Endemic Turkish Species
In the present study, the presence of the phloroglucinol derivative hyperforin, the naphthodianthrones hypericin and pseudohypericin, the phenylpropane chlorogenic acid and the flavonoids rutin, hyperoside, kaempferol, isoquercetine, quercitrine, and ...
Necdet Camas +4 more
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Effects of Hypericum Perforatum, in a rodent model of periodontitis [PDF]
Background Hypericum perforatum is a medicinal plant species containing many polyphenolic compounds, namely flavonoids and phenolic acids. In this study we evaluate the effect of Hypericum perforatum in animal model of periodontitis.
Irene Paterniti +6 more
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Purpose. Drug transporters are increasingly recognized as important determinants of variability in drug disposition and therapeutic response, both in pre-clinical and clinical stages of drug development process.
Alaa H Abuznait +2 more
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Elemental fingerprinting of Hypericum perforatum (St John's Wort) herb and preparations using ICP-OES and chemometrics [PDF]
This is a pre-copyedited, author-produced PDF of an article accepted for publication in Journal of Pharmaceutical and Biomedical Analysis following peer review.
Evans, Sara J. +3 more
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Organisms produce free radicals which are essential for various metabolic processes (enzymatic oxidation, cellular respiration, signaling). Antioxidants are important chemical compounds that specifically prevent the oxidation of substances by scavenging ...
Silke Barbara Lohan +13 more
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Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. [PDF]
Based on its capacity to inhibit in vitro HIV-1 replication in T cells and the release of pro-inflammatory cytokines in monocytes, the prenylated heterodimeric phloroglucinyl α-pyrone arzanol was identified as the major anti-inflammatory and anti-viral ...
Appendino G +8 more
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The Role of Natural Products in Pharmacotherapy of Alzheimer’s Disease [PDF]
Alzheimer’s disease is characterized by forgetfulness, disturbance in memory and loss of mental abilities. The final outcome of the disease is loss of personality and intellectual functions.
Singh, Amrit Pal
core +1 more source

