Results 81 to 90 of about 4,383 (214)

Hypericin and resveratrol anti‐tumor impact through E‐cadherin, N‐cadherin, galectin‐3, and BAX/BCL‐ratio; possible cancer immunotherapy succor on Y79 retinoblastoma cells

open access: yesPrecision Medical Sciences, Volume 14, Issue 3, Page 104-112, September 2025.
Hypericin and Resveratrol can be proposed as beneficial accompanying reagents in cancer immunotherapy and retinoblastoma treatment. Abstract One of the detrimental features of retinoblastoma is highly invasiveness of this type of cancer; the ability to metastasize into distal organs even in the early stages. This phenomenon highlights the importance of
Fatemeh Shahriari   +6 more
wiley   +1 more source

Inhibition of Prostaglandin E2 Production by Anti-inflammatory Hypericum perforatum Extracts and Constituents in RAW264.7 Mouse Macrophage Cells [PDF]

open access: yes, 2007
Hypericum perforatum (Hp) is commonly known for its antiviral, antidepressant, and cytotoxic properties, but traditionally Hp was also used to treat inflammation.
Birt, Diane   +9 more
core   +3 more sources

The Chemical and Antibacterial Evaluation of St. John's Wort Oil Macerates Used in Kosovar Traditional Medicine

open access: yesFrontiers in Microbiology, 2017
Hypericum perforatum L. (Hypericaceae), or St. John's Wort, is a well-known medicinal herb often associated with the treatment of anxiety and depression.
James T. Lyles   +8 more
doaj   +1 more source

Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities [PDF]

open access: yes, 2014
SIRT1, a class III histone deacetylase, plays a critical role in regulating cancer cell growth, migration and invasion, which makes it a potential target for cancer therapeutics.
Chiao, Christine Ya-Chi   +6 more
core   +2 more sources

Characterization of Silver Nanoparticles Synthesized Using Hypericum perforatum L. and Their Effects on Staphylococcus aureus

open access: yesMicroscopy Research and Technique, Volume 88, Issue 8, Page 2321-2332, August 2025.
This study investigated the effects of biosynthesized silver nanoparticles (AgNPs) derived from Hypericum perforatum on the cell morphology of Gram‐positive Staphylococcus aureus bacterial cells, with FE‐SEM analysis showing distinct morphological changes in AgNP‐treated S. aureus cells compared to the control group.
Canan Sevinc‐Sasmaz   +3 more
wiley   +1 more source

Bioactive compounds from Hypericum humifusum and Hypericum perfoliatum: inhibition potential of polyphenols with acetylcholinesterase and key enzymes linked to type-2 diabetes

open access: yesPharmaceutical Biology, 2017
Context: Natural products are reported to have a wide spectrum of pharmacological properties such as antimicrobial, anti-inflammatory and anti-cholinesterase.
Afef Béjaoui   +5 more
doaj   +1 more source

Super Antibiotics, Part I. Hyperforin

open access: yesVoice of the Publisher, 2016
In this series of papers, we will present the appearance of antibiotics in general, from the original animal and microbial natural peptides and proteins, metabolites of molds and yeasts, and bacterial metabolites, to a new generation of plant-based antibiotics.
openaire   +2 more sources

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Human Health and Diseases

open access: yesMedComm, Volume 6, Issue 7, July 2025.
MAM dysfunction is considered as an initiator or contributor in the progression of various diseases such as nervous system diseases, circulatory system diseases, digestive system diseases, locomotor system diseases, reproductive system diseases, endocrine system diseases, urinary system diseases, respiratory system diseases and cancer.
Yong Liu   +10 more
wiley   +1 more source

Phytochemical and antioxidant characterization of Hypericum perforatum alcoholic extracts [PDF]

open access: yes, 1993
The antioxidant potentials of a total ethanolic extract of Hypericum perforatum (TE) and fractions were evaluated and correlated with their phenolic contents. The extracts were fully characterised by HPLC-DAD-MS-MS.
Silva, Bruno A.   +3 more
core   +1 more source

Production of transgenic Hypericum perforatum plants via particle bombardment-mediated transformation of novel organogenic cell suspension cultures [PDF]

open access: yes, 2007
We have developed particle bombardment-mediated transformation procedure for Hypericum perforatum L. (St. John’s wort), an important medicinal species that remains highly recalcitrant towards Agrobacterium-mediated transformation.
Dias, Alberto Carlos Pires   +2 more
core   +1 more source

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