BMJ Open, 2021 Objectives Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. We aimed to investigate the prevalence and risk factors for hyperhomocysteinemia, especially modifiable lifestyle factors, such as smoking behaviour and dietary ...
Yanhui Dong +12 more
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Anemia, hematinic deficiencies, and gastric parietal cell antibody positivity in oral lichen planus patients with or without hyperhomocysteinemia [PDF]
Journal of Dental SciencesBackground/purpose: Our previous study found that 124 of 588 oral lichen planus (OLP) patients have hyperhomocysteinemia. This study assessed whether these 124 OLP patients with hyperhomocysteinemia (hyperhomocysteinemia/OLP patients) had significantly ...
Yi-Pang Lee +5 more
doaj +2 more sources
Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with normocytosis [PDF]
Journal of Dental SciencesBackground/purpose: Normocytosis is defined as having the mean corpuscular volume (MCV) between 80 fL and 99.9 fL. This study evaluated whether the 474 oral lichen planus (OLP) patients with normocytosis (so-called normocytosis/OLP patients) had ...
Julia Yu-Fong Chang +5 more
doaj +2 more sources
Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia. [PDF]
PLoS ONE, 2017 There is an emerging consensus that hyperhomocysteinemia is an independent risk factor for cerebral vascular disease and that homocysteine-lowering therapy protects from ischemic stroke.
Sanjana Dayal +5 more
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Homocysteine enhances the excitability of cultured hippocampal neurons without altering the gene expression of voltage-gated ion channels [PDF]
Molecular BrainElevated plasma homocysteine (Hcy) levels lead to hyperhomocysteinemia, a condition associated with various neurological disorders affecting multiple brain regions, including the hippocampus.
Alzbeta Filipova +8 more
doaj +2 more sources
Association between Elevated Plasma Homocysteine and Low Skeletal Muscle Mass in Asymptomatic Adults [PDF]
Endocrinology and Metabolism, 2022 Background Homocysteine has been drawing attention with a closed linkage with skeletal muscle. However, the association of hyperhomocysteinemia with decreased skeletal muscle mass remains unclear.
Jae-Hyeong Choi +5 more
doaj +1 more source
Journal of the Formosan Medical Association, 2020 Background/Purpose: Our previous study found that 127 of 1064 atrophic glossitis (AG) patients have hyperhomocysteinemia. This study assessed whether the AG patients with hyperhomocysteinemia had significantly higher frequencies of anemia, hematinic ...
Chun-Pin Chiang +5 more
doaj +1 more source
Journal of Dental Sciences, 2020 Background/purpose: Our previous study found that 170 of 884 burning mouth syndrome (BMS) patients have hyperhomocysteinemia. This study assessed whether these 170 BMS patients with hyperhomocysteinemia had significantly higher frequencies of anemia ...
Meng-Ling Chiang +2 more
doaj +1 more source
Effect of hyperhomocysteinemia on a murine model of smoke-induced pulmonary emphysema
Scientific Reports, 2022 Hyperhomocysteinemia was reported to enhance endoplasmic reticulum (ER) stress and subsequent apoptosis in several cells. However, the precise mechanisms of smoking susceptibility associated with hyperhomocysteinemia has not been fully elucidated.
Hiroshi Nakano +16 more
doaj +1 more source
Protective vascular and cardiac effects of inducible nitric oxide synthase in mice with hyperhomocysteinemia. [PDF]
PLoS ONE, 2014 Diet-induced hyperhomocysteinemia produces endothelial and cardiac dysfunction and promotes thrombosis through a mechanism proposed to involve oxidative stress.
Sanjana Dayal +8 more
doaj +1 more source