Results 121 to 130 of about 86,017 (262)

A Retrospective Study of High‐Risk Infants: Insights From a Regional Hospital in Victoria, Australia

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To determine the magnitude of high‐risk infants cared for at a regional hospital in Victoria, Australia and to identify the resources required to care for them. Methods A retrospective study was conducted between January 2017 and December 2019 in a regional hospital in Victoria, Australia.
Romanie Rodrigo, Reji Thomas, Jennifer You, Shizar Nahidi, Sheikh Arif Maqbool Kozgar   +4 more
wiley   +1 more source

Dietary Cholest-4-en-3-one, a Cholesterol Metabolite of Gut Microbiota, Alleviates Hyperlipidemia, Hepatic Cholesterol Accumulation, and Hyperinsulinemia in Obese, Diabetic db/db Mice

Metabolites
Previous studies have shown that dietary cholest-4-en-3-one (4-cholestenone, 4-STN) exerts anti-obesity and lipid-lowering effects in mice. However, its underlying mechanisms are not fully understood.
Mina Higuchi, Mai Okumura, Sarasa Mitsuta, Bungo Shirouchi   +3 more
doaj   +1 more source

Insulin Injections Promote the Growth of Aberrant Crypt Foci in the Colon of Rats [PDF]

, 1997
The main objective of the present study was to test the hypothesis that exogenous insulin would enhance colon carcinogenesis. Thirty-six female F344 rats, fed ad libitum a low fat rodent chow, received a single azoxymethane injection (20 mg/kg), and were
Corpet, Denis E., Jacquinet, Claire, Peiffer, Ginette, Taché, Sylviane   +3 more
core   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Insulin Resistance/Hyperinsulinemia as an Independent Risk Factor That Has Been Overlooked for Too Long

Biomedicines
Unfortunately, cardiovascular diseases and cancers are still the leading causes of death in developed and developing countries despite the considerable progress made in the prevention and treatment of diseases. Maybe we missed something?
Serafino Fazio, Flora Affuso, Arturo Cesaro, Loredana Tibullo, Valeria Fazio, Paolo Calabrò   +5 more
doaj   +1 more source

The effect of a multidisciplinary weight loss program on renal circadian rhythm in obese adolescents

, 2019
Adolescent obesity is a serious health problem associated with many comorbidities. Obesity-related alterations in circadian rhythm have been described for nocturnal blood pressure and for metabolic functions.
Bruneel, Elke, De Guchtenaere, Ann, Dejonckheere, Sarah, Everaert, Karel, Keersmaekers, Laura, Pauwaert, Kim, Roggeman, Saskia, Van der Jeugt, Jolien, Vande Walle, Johan   +8 more
core   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, EarlyView.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source

Sex Differences in [68Ga]Ga‐NODAGA‐Exendin‐4 Uptake in the Pituitary of Individuals With Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Sevilay Tokgöz, Marti Boss, Rick I. Meijer, Theodorus J. P. Jansen, Laura N. Deden, Cees J. Tack, Bastiaan E. de Galan, Martin Gotthardt   +7 more
wiley   +1 more source

Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction–Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole‐Body Fat Metabolism, and Organ‐Specific Lipid Deposition

Obesity Reviews, EarlyView.
ABSTRACT Introduction This narrative review explores the epidemiological evidence and potential underlying pathophysiological defects underlying the disproportionately greater risk of Type 2 diabetes (T2D) and cardiometabolic disease in people of South Asian and African Caribbean ancestry compared with White Europeans.
Daniel J. Cuthbertson, Martin Whyte, Alex E. Henney, Uazman Alam, Louise Goff, Barbara A. Fielding, A. Margot Umpleby   +6 more
wiley   +1 more source

Beyond Glucose: A Brain Energy Bottleneck Hypothesis for Multi‐Energy Substrates in Hypoglycaemia Rescue

Diabetes, Obesity and Metabolism, EarlyView.
D. Russell‐Jones, M. Laffan, J. Mader
wiley   +1 more source