Results 131 to 140 of about 4,983 (216)

Elevated Linoleic Acid Intake Becomes a Risk Factor for Polycystic Ovary Syndrome by Affecting Ovarian Granulosa Cells

open access: yesThe FASEB Journal, Volume 39, Issue 7, 15 April 2025.
This study explored the relationship between dietary LA intake and PCOS. Animal experiments demonstrated that increased intake of LA led to PCOS‐like changes in mice, presenting with disordered estrous cycles, polycystic ovaries, and hyperandrogenism.
Wenying Zhang, Fuju Wu
wiley   +1 more source

Cockayne syndrome: a case with hyperinsulinemia and growth hormone deficiency [PDF]

open access: green, 1994
Sun Kyu Park   +4 more
openalex   +1 more source

Lifestyle‐Related Risk Factors for Pancreatic Ductal Adenocarcinoma: A Longitudinal Analysis of 1,120,377 Individuals From the NHISS Cohort

open access: yesCancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Objective Utilizing data from the National Health Insurance Sharing Service database, this study explored significant risk factors for pancreatic cancer in a cohort of 1,120,377 South Korean individuals over a 10‐year period (2009–2019). Methods Propensity score matching was employed to ensure comparability between 3535 pancreatic cancer ...
Hyunseok Jee
wiley   +1 more source

Association Between Triglyceride‐Glucose Index and Breast Cancer: A Systematic Review and Meta‐Analysis

open access: yesCancer Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims The triglyceride‐glucose (TyG) index, a surrogate marker for insulin resistance and metabolic syndrome, has been implicated in breast cancer (BC) risk. However, its predictive value remains controversial. This systematic review and meta‐analysis assessed the association between the TyG index and BC risk, its role in ...
Diar Zooravar   +3 more
wiley   +1 more source

Gout in pregnancy: Obstetric and neonatal outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar   +3 more
wiley   +1 more source

Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Activation of mitochondrial fission and quality control occur early in the onset of insulin resistance in human skeletal muscle. We hypothesized that differences in mitochondrial dynamics, structure and bioenergetics in humans would explain the onset and progression of type 2 diabetes (T2D). Methods Fifty‐eight sedentary adults (37 ±
Wagner S. Dantas   +12 more
wiley   +1 more source

Estimated Glucose Disposal Rate Associated With Risk of Frailty and Likelihood of Reversion

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Estimated glucose disposal rate (eGDR) is a simple and effective measure for insulin resistance, which is associated with higher risk of frailty. We aim to analyse the associations of eGDR with frailty risk and its reversibility. Methods A population‐based longitudinal study was conducted of 11 670 participants from the China Health
Dingchun Hou   +6 more
wiley   +1 more source

Essential fatty acid deficiency in parenteral nutrition: Historical perspective and modern solutions, a narrative review

open access: yesNutrition in Clinical Practice, Volume 40, Issue 2, Page 350-367, April 2025.
Abstract Essential fatty acid deficiency (EFAD) may occur in the setting of inadequate fat intake, malabsorption, malnutrition, and altered fat metabolism. Humans lack the enzymes to synthesize the essential acids linoleic acid and alpha‐linolenic acid, so they must be obtained from the diet.
Jodi Wolff   +2 more
wiley   +1 more source

Maternal and Cord Blood Lipids in Pregnant Women With Obesity and Their Impact on Neonatal and Placental Biometric Features

open access: yesObesity Science &Practice, Volume 11, Issue 2, April 2025.
ABSTRACT Objective Maternal obesity and excessive weight gain during pregnancy predispose to adverse fetal outcomes and health issues for the offspring. Although maternal lipids play an important role in excess fetal fat accretion, previous studies found heterogeneous results regarding which lipid fraction is most involved in excessive fetal growth in ...
Fausta Beneventi   +9 more
wiley   +1 more source

The Correlation Between Body Mass Index and Prostate Volume: A Retrospective Analysis of Pre and Postoperative Measurements in Prostate Cancer Patients

open access: yesThe Prostate, Volume 85, Issue 5, Page 433-442, April 2025.
ABSTRACT Background This study aims to assess the relationship between body mass index (BMI) and prostate volume, utilizing pre and postoperative measurements. Methods A retrospective, observational study was conducted at a single site using data from an institutional database.
Biagio Barone   +18 more
wiley   +1 more source

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