Results 171 to 180 of about 103,854 (365)

Hyperinsulinemia Drives Epithelial Tumorigenesis by Abrogating Cell Competition.

Developmental Cell, 2020
Y. Sanaki, Rina Nagata, Daisuke Kizawa, P. Léopold, T. Igaki   +4 more
semanticscholar   +1 more source

Exploring the Role of Kisspeptin in Polycystic Ovary Syndrome and Its Associated Pregnancy Complications

Obesity Reviews, EarlyView.
ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang, Xinmeng Sun, Haiyun Guan, Rongmin Wang, Wei Zhang, Hexia Xia   +5 more
wiley   +1 more source

Dietary Cholest-4-en-3-one, a Cholesterol Metabolite of Gut Microbiota, Alleviates Hyperlipidemia, Hepatic Cholesterol Accumulation, and Hyperinsulinemia in Obese, Diabetic db/db Mice

Metabolites
Previous studies have shown that dietary cholest-4-en-3-one (4-cholestenone, 4-STN) exerts anti-obesity and lipid-lowering effects in mice. However, its underlying mechanisms are not fully understood.
Mina Higuchi, Mai Okumura, Sarasa Mitsuta, Bungo Shirouchi   +3 more
doaj   +1 more source

Cockayne syndrome: a case with hyperinsulinemia and growth hormone deficiency [PDF]

, 1994
Sun Kyu Park, Soo Hee Chang, Seog Beom Cho, Hong Sun Baek, Dae Yeol Lee   +4 more
openalex   +1 more source

Effect of phenylbutazone on insulin secretion in horses with insulin dysregulation

Journal of Veterinary Internal Medicine
Background Phenylbutazone is often prescribed to manage pain caused by hyperinsulinemia‐associated laminitis, but in diabetic people nonsteroidal anti‐inflammatory drugs increase insulin secretion and pancreatic activity.
Kate L. Kemp, Jazmine E. Skinner, François‐René Bertin   +2 more
doaj   +1 more source

Insulin Resistance/Hyperinsulinemia as an Independent Risk Factor That Has Been Overlooked for Too Long

Biomedicines
Unfortunately, cardiovascular diseases and cancers are still the leading causes of death in developed and developing countries despite the considerable progress made in the prevention and treatment of diseases. Maybe we missed something?
Serafino Fazio, Flora Affuso, Arturo Cesaro, Loredana Tibullo, Valeria Fazio, Paolo Calabrò   +5 more
doaj   +1 more source

Effect of vagotomy on hyperinsulinemia in obese rats with hypothalamic lesions.

, 1977
K Chikamori, Akiko Masuda, Hidehiko Izumi, Katsutoshi ISAKA, UICHIRO TEZUKA   +4 more
openalex   +2 more sources

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

The Journal of Physiology, EarlyView.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid, Francisco Algaba‐Chueca, Elsa Maymó‐Masip, Mónica Ballesteros, Montse Inglés, Albert Guarque, Nerea Vilanova‐Ricart, Ariadna Prats, Azra Kulovic‐Sissawo, Elisa Weiss, Ursula Hiden, Joan Vendrell, Sonia Fernández‐Veledo, Ana Megía   +13 more
wiley   +1 more source

Chronically Increased Levels of Circulating Insulin Secondary to Insulin Resistance: A Silent Killer

Biomedicines
Despite all the progress made by science in the prevention and treatment of cardiovascular diseases and cancers, these are still the main reasons for hospitalizations and death in the Western world.
Serafino Fazio, Paolo Bellavite, Flora Affuso   +2 more
doaj   +1 more source

Insulin Resistance: From Theory To Practice [PDF]

, 2006
Insulin resistance is at the core of the well recognised metabolic syndrome and possibly many other ailments commonly seen in the modern society. While the quantification of insulin resistance remains a difficult task, the problems associated with it are
Kakkilaya Bevinje, Dr. Srinivas
core   +1 more source