Impaired Feedback Inhibition of Insulin Secretion by Hyperinsulinemia in Patients with Insulinoma.
, 1995 Shinsuke Hiramatsu +7 more
openalex +2 more sources
Hyperinsulinemia. A link between hypertension obesity and glucose intolerance. [PDF]
, 1985 Michaela Modan +7 more
openalex +1 more source
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Journal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli +12 more
wiley +1 more source
Metabolic and appetitive regulation of adipocyte mass during treatment of obesity
Journal of Internal Medicine, Volume 299, Issue 1, Page 66-78, January 2026.Abstract Adipose mass is homeostatically maintained within a narrow range despite fluctuations in daily calorie intake and activity levels. Constituting an adipose mass “set point,” this homeostatic regulation includes sensing mechanisms in the form of hormones reflecting caloric intake that serve as mediators of appetitive behaviors and adipose mass ...
Jonathan Q. Purnell, Carel W. Le Roux
wiley +1 more source
Human Cancers Derived from Either Genetic or Lifestyle Factors Are Initiated by Impaired Estrogen Signaling. [PDF]
Cancers (Basel)Suba Z.
europepmc +1 more source
Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo
, 2008 Dawn K. Coletta +11 more
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Obesity Reviews, Volume 27, Issue 1, Page 1-21, January 2026.ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang +5 more
wiley +1 more source
Innovations in early detection of chronic non-communicable diseases among adolescents through an easy-to-Use AutoML paradigm. [PDF]
Health Care Manag SciRankovic N, Rankovic D, Lukic I.
europepmc +1 more source
Primary Acid-Labile Subunit Deficiency due to RecessiveIGFALSMutations Results in Postnatal Growth Deficit Associated with Low Circulating Insulin Growth Factor (IGF)-I, IGF Binding Protein-3 Levels, and Hyperinsulinemia [PDF]
, 2008 Karen E. Heath +8 more
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Veterinary Surgery, Volume 55, Issue 1, Page 236-247, January 2026.Abstract Objective To describe outcomes following high‐metacarpal deep digital flexor tenotomy (DDFT) combined with Steward clog application in horses and ponies with refractory chronic laminitis. Study design Retrospective observational study. Animals Client‐owned horses and ponies (7 horses, 8 ponies) with severe refractory laminitis. Methods Medical
Kristyna Hargitaiova, Grigorios Maleas
wiley +1 more source